FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care

Autor: Ramnarayan, P, Lister, P, Dominguez, T, Habibi, P, Edmonds, N, Canter, RR, Wulff, J, Harrison, DA, Mouncey, PM, Peters, MJ

Background Although high-flow nasal cannula therapy (HFNC) has become a popular mode of non-invasive respiratory support (NRS) in critically ill children, there are no randomised controlled trials (RCTs) comparing it with continuous positive airway p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::26d85e7b63e88c0e6017eebd5cfafe14
http://hdl.handle.net/10044/1/97911

Operationalising kangaroo Mother care before stabilisation amongst low birth Weight Neonates in Africa (OMWaNA): protocol for a randomised controlled trial to examine mortality impact in Uganda.

Autor: Medvedev MM; Maternal, Adolescent, Reproductive, & Child Health Centre, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Melissa.Morgan@lshtm.ac.uk.; Department of Paediatrics, University of California San Francisco, 550 16th Street, Box 1224, San Francisco, CA, 94158, USA. Melissa.Morgan@lshtm.ac.uk.; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Melissa.Morgan@lshtm.ac.uk., Tumukunde V; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda., Mambule I; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda., Tann CJ; Maternal, Adolescent, Reproductive, & Child Health Centre, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda.; Department of Neonatal Medicine, University College London, 235 Euston Road, London, NW1 2BU, UK., Waiswa P; Centre of Excellence for Maternal, Newborn, and Child Health, School of Public Health, Makerere University, New Mulago Hill Road, Kampala, Uganda.; Department of Public Health Sciences, Karolinska Institutet, SE-171 77, Stockholm, Sweden., Canter RR; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Hansen CH; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda., Ekirapa-Kiracho E; Centre of Excellence for Maternal, Newborn, and Child Health, School of Public Health, Makerere University, New Mulago Hill Road, Kampala, Uganda., Katumba K; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda., Pitt C; Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, WC1E 7HT, UK., Greco G; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda.; Centre of Excellence for Maternal, Newborn, and Child Health, School of Public Health, Makerere University, New Mulago Hill Road, Kampala, Uganda.; Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, WC1E 7HT, UK., Brotherton H; Maternal, Adolescent, Reproductive, & Child Health Centre, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Medical Research Council Unit The Gambia at LSHTM, PO Box 273, Fajara, The Gambia., Elbourne D; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Seeley J; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda.; Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, WC1E 7HT, UK., Nyirenda M; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Medical Research Council/Uganda Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda., Allen E; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Lawn JE; Maternal, Adolescent, Reproductive, & Child Health Centre, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

Publikováno v: Trials [Trials] 2020 Jan 31; Vol. 21 (1), pp. 126. Date of Electronic Publication: 2020 Jan 31.

FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care.

Autor: Ramnarayan P; Children's Acute Transport Service, Critical Care Division, Great Ormond Street Hospital NHS Foundation Trust, 26-27 Boswell Street, London, WC1N 3JZ, UK. p.ramnarayan@gosh.nhs.uk.; Paediatric Intensive Care Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK. p.ramnarayan@gosh.nhs.uk., Lister P; Paediatric and Neonatal Intensive Care Unit, Critical Care Division, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Dominguez T; Cardiac Intensive Care Unit, Critical Care Division, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Habibi P; Paediatric Intensive Care Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK., Edmonds N; Paediatric Critical Care Unit, Royal London Hospital, Barts Health NHS Trust, London, UK., Canter RR; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), Napier House, High Holborn, London, UK., Wulff J; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), Napier House, High Holborn, London, UK., Harrison DA; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), Napier House, High Holborn, London, UK., Mouncey PM; Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), Napier House, High Holborn, London, UK., Peters MJ; Paediatric and Neonatal Intensive Care Unit, Critical Care Division, Great Ormond Street Hospital NHS Foundation Trust, London, UK.; Respiratory, Critical Care and Anaesthesia Unit, Infection, Immunity and Inflammation Programme, UCL Great Ormond Street Institute of Child Health, London, UK.

Publikováno v: Critical care (London, England) [Crit Care] 2018 Jun 04; Vol. 22 (1), pp. 144. Date of Electronic Publication: 2018 Jun 04.

Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.

Autor: Rowan KM; Intensive Care National Audit and Research Centre, London, United Kingdom, Angus DC; University of Pittsburgh School of Medicine, Pittsburgh, Bailey M; Monash University, Melbourne, VIC, Australia, Barnato AE; University of Pittsburgh School of Medicine, Pittsburgh, Bellomo R; Monash University, Melbourne, VIC, Australia, Canter RR; Intensive Care National Audit and Research Centre, London, United Kingdom, Coats TJ; University of Leicester, Leicester, United Kingdom, Delaney A; University of Sydney, Sydney, Australia, Gimbel E; University of Pittsburgh School of Medicine, Pittsburgh, Grieve RD; London School of Hygiene and Tropical Medicine, London, United Kingdom, Harrison DA; Intensive Care National Audit and Research Centre, London, United Kingdom, Higgins AM; Monash University, Melbourne, VIC, Australia, Howe B; Monash University, Melbourne, VIC, Australia, Huang DT; University of Pittsburgh School of Medicine, Pittsburgh, Kellum JA; University of Pittsburgh School of Medicine, Pittsburgh, Mouncey PR; Intensive Care National Audit and Research Centre, London, United Kingdom, Music E; University of Pittsburgh School of Medicine, Pittsburgh, Peake SL; Monash University, Melbourne, VIC, Australia; University of Adelaide, Adelaide, SA, Australia; Queen Elizabeth Hospital, Adelaide, SA, Australia, Pike F; Eli Lilly, Indianapolis, Reade MC; University of Queensland, Brisbane, Australia, Sadique MZ; London School of Hygiene and Tropical Medicine, London, United Kingdom, Singer M; University College London, London, United Kingdom, Yealy DM; University of Pittsburgh School of Medicine, Pittsburgh

Publikováno v: The New England journal of medicine [N Engl J Med] 2017 Jun 08; Vol. 376 (23), pp. 2223-2234. Date of Electronic Publication: 2017 Mar 21.

A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES).

Autor: Harvey SE; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., Parrott F; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., Harrison DA; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., Sadique MZ; Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK., Grieve RD; Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK., Canter RR; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., McLennan BK; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., Tan JC; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK., Bear DE; Department of Nutrition and Dietetics, Guy's and St Thomas' NHS Foundation Trust, London, UK., Segaran E; Department of Nutrition and Dietetics, Imperial College Healthcare NHS Trust, London, UK., Beale R; Division of Asthma, Allergy and Lung Biopsy, King's College London, London, UK., Bellingan G; National Institute for Health Research Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK., Leonard R; Department of Critical Care, Imperial College Healthcare NHS Trust, London, UK., Mythen MG; National Institute for Health Research Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK., Rowan KM; Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK.

Publikováno v: Health technology assessment (Winchester, England) [Health Technol Assess] 2016 Apr; Vol. 20 (28), pp. 1-144.