Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cansu Colpan"'
Autor:
Stephen Lyle, Kathleen Hoover, Cansu Colpan, Zhiqing Zhu, Zdenka Matijasevic, Stephen N Jones
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100920 (2014)
Dicer is required for the maturation of microRNA, and loss of Dicer and miRNA processing has been found to alter numerous biological events during embryogenesis, including the development of mammalian skin and hair. We have previously examined the ro
Externí odkaz:
https://doaj.org/article/8a6ec3b5dab74774ae139d180ce21643
Autor:
Pei Hsuan Wu, Yu Fu, Phillip D. Zamore, Katharine Cecchini, Cansu Colpan, Amena Arif, Tianxiong Yu, Deniz M. Ozata, Zhiping Weng, Ildar Gainetdinov
Publikováno v:
Nature genetics, Vol. 52, No 7 (2020) pp. 728-739
Pachytene PIWI-interacting RNAs (piRNAs), which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like microRNAs, cleave targets like short interfering RNAs or lack biological function altogeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e3488b621c481bfc2eae3efe9718cb
https://doi.org/10.1038/s41588-020-0657-7
https://doi.org/10.1038/s41588-020-0657-7
Autor:
Jia Li, Yi Wang, Phillip W. L. Tai, Guangping Gao, Phillip D. Zamore, Ran He, Chengjian Li, Shoufang Gong, Jihye Ko, Hanqing Ye, Qin Su, Jun Xie, Sha Zhu, Alexander Brown, Cansu Colpan, Hong Ma
Publikováno v:
Mol Ther
Short hairpin RNAs that are delivered by recombinant adeno-associated virus (rAAV) have the potential to elicit long-term RNAi therapy for human disease. However, the discovery that short hairpin sequences can cause truncation of the rAAV genome call
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7800d37595700a7c9bdbfb749bf9b772
https://doi.org/10.1016/j.ymthe.2019.11.018
https://doi.org/10.1016/j.ymthe.2019.11.018
Autor:
Tianxiong Yu, Katharine Cecchini, Phillip D. Zamore, Alper Kucukural, Yasin Kaymaz, Cansu Colpan, Kaili Fan, Zhiping Weng, Haiwei Mou, Pei Hsuan Wu, Ildar Gainetdinov, Deniz M. Ozata
Publikováno v:
Nature ecology & evolution
Nature ecology & evolution, Vol. 4, No 1 (2020) pp. 156-168
Nature ecology & evolution, Vol. 4, No 1 (2020) pp. 156-168
In the fetal mouse testis, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons but, after birth, most post-pubertal pachytene piRNAs map to the genome uniquely and are thought to regulate genes required for male fertility. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30be6aecd5ec4b99bbf08b63c23dba2b
https://doi.org/10.1038/s41559-019-1065-1
https://doi.org/10.1038/s41559-019-1065-1
Autor:
Haiwei Mou, Dirk G. de Rooij, Katharine Cecchini, Zhiping Weng, Cansu Colpan, Ildar Gaitendinov, Tianxiong Yu, Adriano Biasini, Phillip D. Zamore, Amena Arif, Deniz M. Ozata
In male mice, the transcription factor (TF) A-MYB initiates reprogramming of gene expression after spermatogonia enter meiosis. We report that A-MYB activates Tcfl5, a testis-specific TF first produced in pachytene spermatocytes. Subsequently, A-MYB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b403ce23eb4a8e9dc46d72d43e03b015
https://doi.org/10.1101/2021.04.04.438419
https://doi.org/10.1101/2021.04.04.438419
Autor:
Yongjin Lee, Karina Jouravleva, Paul Albosta, Phillip D. Zamore, Cansu Colpan, Katharine Cecchini, Joel Vega-Badillo, Ildar Gainetdinov, Deniz M. Ozata
In animals, piRNAs, siRNAs, and miRNAs silence transposons, fight viral infections, and regulate gene expression. piRNA biogenesis concludes with 3′ terminal trimming and 2′-O-methylation. Both trimming and methylation influence piRNA stability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec13880fe6457b03036231b384a472a
https://doi.org/10.1101/2020.09.08.287979
https://doi.org/10.1101/2020.09.08.287979
Autor:
Ildar Gainetdinov, Phillip D. Zamore, Joel Vega-Badillo, Katharine Cecchini, Amena Arif, Yongjin Lee, Paul Albosta, Deniz M. Ozata, Cansu Colpan, Karina Jouravleva
Publikováno v:
Mol Cell
Summary In animals, PIWI-interacting RNAs (piRNAs) silence transposons, fight viral infections, and regulate gene expression. piRNA biogenesis concludes with 3′ terminal trimming and 2′-O-methylation. Both trimming and methylation influence piRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91fa9ea93de266dda50ebe3ca48def6
https://doi.org/10.1016/j.molcel.2021.09.012
https://doi.org/10.1016/j.molcel.2021.09.012
Autor:
Pei-Hsuan, Wu, Yu, Fu, Katharine, Cecchini, Deniz M, Özata, Amena, Arif, Tianxiong, Yu, Cansu, Colpan, Ildar, Gainetdinov, Zhiping, Weng, Phillip D, Zamore
Publikováno v:
Nature genetics. 52(7)
Pachytene PIWI-interacting RNAs (piRNAs), which comprise80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like microRNAs, cleave targets like short interfering RNAs or lack biological function altogether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31ebae281e555e52400d856b418bc5a6
https://pubmed.ncbi.nlm.nih.gov/33356461
https://pubmed.ncbi.nlm.nih.gov/33356461
Autor:
Tianxiong Yu, Amena Arif, Deniz M. Ozata, Philip D. Zamore, Katharine Cecchini, Pei Hsuan Wu, Cansu Colpan, Yu Fu, Ildar Gainetdinov, Zhiping Weng
SUMMARYPachytene piRNAs, which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like miRNAs, cleave targets like siRNAs, or lack biological function altogether. Although piRNA pathway protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7f9856279f1bc8f868583c5a3f2c07
Publikováno v:
Molecular cell. 71(5)
Summary In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and regulate gene expression. The mechanisms for making piRNAs have been proposed to differ among cell types, tissues, and animals. Our data instead suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2006305355f162e0e6a905f40f6d3e
https://pubmed.ncbi.nlm.nih.gov/30193093
https://pubmed.ncbi.nlm.nih.gov/30193093