Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis.

Autor: Phan J; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Chen B; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Zhao Z; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Allies G; Department of Dermatology, University Hospital Essen & German Cancer Consortium, Essen, & National Center for Tumor Diseases (NCT-West), Campus Essen & Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., Iannaccone A; Department of Gynecology and Obstetrics, University Hospital Essen, 45147 Essen, Germany., Paul A; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Cansiz F; Department of Dermatology, University Hospital Essen & German Cancer Consortium, Essen, & National Center for Tumor Diseases (NCT-West), Campus Essen & Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., Spina A; Department of Gynecology and Obstetrics, University Hospital Essen, 45147 Essen, Germany., Leven AS; Department of Dermatology, University Hospital Essen & German Cancer Consortium, Essen, & National Center for Tumor Diseases (NCT-West), Campus Essen & Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., Gellhaus A; Department of Gynecology and Obstetrics, University Hospital Essen, 45147 Essen, Germany., Schadendorf D; Department of Dermatology, University Hospital Essen & German Cancer Consortium, Essen, & National Center for Tumor Diseases (NCT-West), Campus Essen & Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., Kimmig R; Department of Gynecology and Obstetrics, University Hospital Essen, 45147 Essen, Germany., Mettlen M; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA., Tasdogan A; Department of Dermatology, University Hospital Essen & German Cancer Consortium, Essen, & National Center for Tumor Diseases (NCT-West), Campus Essen & Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., Morrison SJ; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Nov 08; Vol. 386 (6722), pp. eado6836. Date of Electronic Publication: 2024 Nov 08.

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.

Autor: Lang J; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Bohn P; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Bhat H; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Jastrow H; Institute of Anatomy, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany.; Institut for Experimental Immunology and Imaging, Imaging Center Essen, Electron Microscopy Unit, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Walkenfort B; Institut for Experimental Immunology and Imaging, Imaging Center Essen, Electron Microscopy Unit, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Cansiz F; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Fink J; Institute of Organic Chemistry, Julius-Maximilians University of Würzburg, Am Hubland, Würzburg, D-97074, Germany., Bauer M; Department of Molecular Life Sciences, University of Zurich, Winterthurerstr. 190, CH-8057, Zurich, Switzerland., Olszewski D; Department of Molecular Life Sciences, University of Zurich, Winterthurerstr. 190, CH-8057, Zurich, Switzerland., Ramos-Nascimento A; Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover, D-30625, Germany., Duhan V; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Friedrich SK; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Becker KA; Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Krawczyk A; Institute for Virology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany.; Department of Infectious Diseases, University Hospital of Essen, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Edwards MJ; Department of Surgery, University of Cincinnati, Cincinnati, OH, USA., Burchert A; Department of Hematology, Oncology and Immunology, University Hospital Giessen and Marburg, Campus Marburg, Baldingerstr., Marburg, D-35043, Germany., Huber M; Institute of Medical Microbiology and Hospital Hygiene, Philipps-University Marburg, Hans-Meerwein Str. 2, Marburg, D-35043, Germany., Friebus-Kardash J; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Göthert JR; Department of Hematology, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Hardt C; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany., Probst HC; Institute of Immunology, University Medical Center Mainz, Langenbeckstr. 1, Mainz, D-55131, Germany., Schumacher F; Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany.; Institute of Nutritional Science, University of Potsdam, Arthur-Scheunert Allee 114-116, Nuthetal, D-14558, Germany., Köhrer K; Biological and Medical Research Center (BMFZ), Heinrich-Heine-University, Universitätsstr. 1, Düsseldorf, D-40225, Germany., Kleuser B; Institute of Nutritional Science, University of Potsdam, Arthur-Scheunert Allee 114-116, Nuthetal, D-14558, Germany., Babiychuk EB; Institute of Anatomy, University of Bern, Baltzerstr. 4, CH-3012, Bern, Switzerland., Sodeik B; Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover, D-30625, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Carl-Neuberg-Str. 1, Hannover, D-30625, Germany., Seibel J; Institute of Organic Chemistry, Julius-Maximilians University of Würzburg, Am Hubland, Würzburg, D-97074, Germany., Greber UF; Department of Molecular Life Sciences, University of Zurich, Winterthurerstr. 190, CH-8057, Zurich, Switzerland., Lang PA; Department of Molecular Medicine II, Medical Faculty, Heinrich Heine University, Universitätsstr. 1, Düsseldorf, D-40225, Germany., Gulbins E; Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany.; Department of Surgery, University of Cincinnati, Cincinnati, OH, USA., Lang KS; Institute of Immunology, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45147, Germany. karlsebastian.lang@uk-essen.de.

Publikováno v: Nature communications [Nat Commun] 2020 Mar 12; Vol. 11 (1), pp. 1338. Date of Electronic Publication: 2020 Mar 12.

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Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to Mycobacterium abscessus Infections.

Autor: Schnitker, Fabian¹ (AUTHOR) fabian.schnitker@stud.uni-due.de, Liu, Yongjie^1,2 (AUTHOR) markus.kamler@uk-essen.de, Keitsch, Simone¹ (AUTHOR) simone.keitsch@uk-essen.de, Soddemann, Matthias¹ (AUTHOR) matthias.soddemann@uk-essen.de, Verhasselt, Hedda Luise³ (AUTHOR) hedda-luise.verhasselt@uk-essen.de, Kehrmann, Jan³ (AUTHOR) jan.kehrmann@uk-essen.de, Grassmé, Heike¹ (AUTHOR) heike.gulbins@uk-essen.de, Kamler, Markus² (AUTHOR), Gulbins, Erich^1,4 (AUTHOR) erich.gulbins@uk-essen.de, Wu, Yuqing¹ (AUTHOR) yuqing.wu@uk-essen.de

Publikováno v: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 18, p14004. 18p.

Azido-Ceramides, a Tool to Analyse SARS-CoV-2 Replication and Inhibition—SARS-CoV-2 Is Inhibited by Ceramides.

Autor: Brenner, Daniela¹ (AUTHOR) daniela.brenner@uni-wuerzburg.de, Geiger, Nina² (AUTHOR) nina.geiger@stud-mail.uni-wuerzburg.de, Schlegel, Jan³ (AUTHOR) jan.schlegel@scilifelab.se, Diesendorf, Viktoria² (AUTHOR) viktoria.diesendorf@stud-mail.uni-wuerzburg.de, Kersting, Louise¹ (AUTHOR) louise.kersting@uni-wuerzburg.de, Fink, Julian¹ (AUTHOR), Stelz, Linda³ (AUTHOR) m.sauer@uni-wuerzburg.de, Schneider-Schaulies, Sibylle² (AUTHOR), Sauer, Markus³ (AUTHOR), Bodem, Jochen² (AUTHOR) jochen.bodem@uni-wuerzburg.de, Seibel, Jürgen¹ (AUTHOR) jochen.bodem@uni-wuerzburg.de

Publikováno v: International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p7281. 9p.