Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency.

Autor: Surucu Yilmaz N; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Bilgic Eltan S; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Kayaoglu B; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Geckin B; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Heredia RJ; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria., Sefer AP; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Kiykim A; Faculty of Medicine, Pediatric Allergy and Immunology, Istanbul University-Cerrahpasa, Istanbul, Turkey., Nain E; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Kasap N; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Dogru O; Division of Pediatric Hematology-Oncology, Marmara University, Istanbul, Turkey., Yucelten AD; Division of Dermatology, Marmara University, Istanbul, Turkey., Cinel L; Division of Pathology, Marmara University, Istanbul, Turkey., Karasu G; Goztepe Medicalpark Hospital, Pediatric Stem Cell Transplantation Unit, İstanbul, Turkey., Yesilipek A; Goztepe Medicalpark Hospital, Pediatric Stem Cell Transplantation Unit, İstanbul, Turkey., Sozeri B; Division of Pediatric Rheumatology, University of Health Sciences, Umraniye Research and Training Hospital, Istanbul, Turkey., Kaya GG; Therapeutic ODN Research Lab, Department of Molecular Biology and Genetics, Bilkent University, Bilkent, 06800, Ankara, Turkey., Yilmaz IC; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Baydemir I; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Aydin Y; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey., Cansen Kahraman D; KanSiL, Department of Health Informatics, Graduate School of Informatics, Middle East Technical University, Ankara, Turkey., Haimel M; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Boztug K; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.; St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria., Karakoc-Aydiner E; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Gursel I; Therapeutic ODN Research Lab, Department of Molecular Biology and Genetics, Bilkent University, Bilkent, 06800, Ankara, Turkey., Ozen A; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Baris S; Division of Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Istanbul, Turkey. safabaris@hotmail.com.; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey. safabaris@hotmail.com.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey. safabaris@hotmail.com., Gursel M; Department of Biological Sciences, Middle East Technical University, B-58, Üniversiteler Mah. Dumlupınar Bulvarı No:1, Ankara, Turkey. mgursel@metu.edu.tr.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2022 Apr; Vol. 42 (3), pp. 582-596. Date of Electronic Publication: 2022 Jan 14.

Drug Repurposing Approach to Identify Candidate Drug Molecules for Hepatocellular Carcinoma.

Autor: Baser, Tugce¹ (AUTHOR) e148008@metu.edu.tr, Rifaioglu, Ahmet Sureyya^2,3 (AUTHOR), Atalay, Mehmet Volkan⁴ (AUTHOR), Atalay, Rengul Cetin¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9392. 20p.

KGE-UNIT: toward the unification of molecular interactions prediction based on knowledge graph and multi-task learning on drug discovery.

Autor: Zhang, Chengcheng¹ (AUTHOR), Zang, Tianyi¹ (AUTHOR) tianyi.zang@hit.edu.cn, Zhao, Tianyi² (AUTHOR) tianyi.zang@hit.edu.cn

Publikováno v: Briefings in Bioinformatics. Mar2024, Vol. 25 Issue 2, p1-12. 12p.

SAM-DTA: a sequence-agnostic model for drug–target binding affinity prediction.

Autor: Hu, Zhiqiang¹ (AUTHOR) huzhiqiang@sensetime.com, Liu, Wenfeng^2,3 (AUTHOR), Zhang, Chenbin¹ (AUTHOR), Huang, Jiawen^2,3 (AUTHOR), Zhang, Shaoting^1,4 (AUTHOR), Yu, Huiqun³ (AUTHOR), Xiong, Yi⁵ (AUTHOR), Liu, Hao^2,6 (AUTHOR), Ke, Song² (AUTHOR) huzhiqiang@sensetime.com, Hong, Liang^4,5,6,7,8 (AUTHOR)

Publikováno v: Briefings in Bioinformatics. Jan2023, Vol. 24 Issue 1, p1-15. 15p.

Improved drug–target interaction prediction with intermolecular graph transformer.

Autor: Liu, Siyuan^1,2,3 (AUTHOR), Wang, Yusong^3,4 (AUTHOR), Deng, Yifan³ (AUTHOR), He, Liang^3,5 (AUTHOR), Shao, Bin³ (AUTHOR), Yin, Jian^1,2 (AUTHOR), Zheng, Nanning⁴ (AUTHOR), Liu, Tie-Yan³ (AUTHOR), Wang, Tong³ (AUTHOR) watong@microsoft.com

Publikováno v: Briefings in Bioinformatics. Sep2022, Vol. 23 Issue 5, p1-10. 10p.