Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Canping Chen"'
Autor:
Pallawi Torka, Swetha Kambhampati Thiruvengadam, Lu Chen, Xiaoguang Wang, Canping Chen, Dan Vuong, Hanjun Qin, Alexandra Muir, Kirsten Orand, Ivana Borja, D. Lynne Smith, Alex F. Herrera, Stephen E. F. Spurgeon, Byung Park, Lionel D. Lewis, Francisco Hernandez-Ilizaliturri, Zheng Xia, Alexey V. Danilov
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Pevonedistat (TAK924) is a Nedd8-activating enzyme inhibitor with preclinical activity in non-Hodgkin lymphoma (NHL). This open-label, Phase I, multicenter, investigator-sponsored study enrolled patients with relapsed/refractory (R/R) NHL an
Externí odkaz:
https://doaj.org/article/dbdbd858a48d43e9ada471af5afef924
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Splicing abnormality resulting from somatic mutations in key splicing factor genes (SFG) has been detected in various cancers. Hence, an in-depth study of splicing factor genes mutations’ impact on pan-cancer is meaningful. This study investigated
Externí odkaz:
https://doaj.org/article/c5e5fd2dcc6b475b9f27e008b3dc1459
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5428-5442 (2021)
Alterations in the spliceosome pathway (SP) have been associated with diverse human cancers. In this study, we explored associations of the SP activity with various clinical features, anti-tumor immune signatures, tumor immunity-related genomic and m
Externí odkaz:
https://doaj.org/article/78e23d3d3daf4a8ba683d8a901ad34f7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
E1A binding protein p300 (EP300) is mutated in diverse cancers. Nevertheless, a systematic investigation into the associations of EP300 mutations with genome instability and antitumor immunity in pan-cancer remains lacking. Using the datasets from Th
Externí odkaz:
https://doaj.org/article/af28e2de45cb4553b676ee4e818c5b80
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background kalirin RhoGEF kinase (KALRN) is mutated in a wide range of cancers. Nevertheless, the association between KALRN mutations and the pathogenesis of cancer remains unexplored. Identification of biomarkers for cancer immunotherapy response is
Externí odkaz:
https://doaj.org/article/dab62e2b19d24c6d8e0153ad453a3886
Autor:
Xiaoguang Wang, Canping Chen, Dan Vuong, Sonia Rodriguez-Rodriguez, Vi Lam, Carly Roleder, Jing H. Wang, Swetha Kambhampati, Allison Berger, Nathan Pennock, Pallawi Torka, Francisco Hernandez-Ilizaliturri, Tanya Siddiqi, Lili Wang, Zheng Xia, Alexey V. Danilov
Publikováno v:
Leukemia.
Neddylation is a sequential enzyme-based process which regulates the function of E3 Cullin-RING ligase (CRL) and thus degradation of substrate proteins. Here we show that CD8+ T cells are a direct target for therapeutically relevant anti-lymphoma act
Autor:
Tao Ren, Canping Chen, Alexey V. Danilov, Susan Liu, Xiangnan Guan, Shunyi Du, Xiwei Wu, Mara H. Sherman, Paul T. Spellman, Lisa M. Coussens, Andrew C. Adey, Gordon B. Mills, Ling-Yun Wu, Zheng Xia
Publikováno v:
bioRxiv
Accurately identifying phenotype-relevant cell subsets from heterogeneous cell populations is crucial for delineating the underlying mechanisms driving biological or clinical phenotypes. Here, by deploying a learning with rejection strategy, we devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1c84727d626f0aa3ddb6e446a4b8df
https://doi.org/10.1101/2023.03.23.533712
https://doi.org/10.1101/2023.03.23.533712
Publikováno v:
Medical Oncology. 39
Prostate cancer (PC) is heterogeneous in the tumor immune microenvironment (TIME). Subtyping of PC based on the TIME could provide new insights into intratumor heterogeneity and its correlates of clinical features. Based on the enrichment scores of 2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5428-5442 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Alterations in the spliceosome pathway (SP) have been associated with diverse human cancers. In this study, we explored associations of the SP activity with various clinical features, anti-tumor immune signatures, tumor immuni
Alterations in the spliceosome pathway (SP) have been associated with diverse human cancers. In this study, we explored associations of the SP activity with various clinical features, anti-tumor immune signatures, tumor immuni
Autor:
Zhixian HOU1, Canping CHEN1 918548YY9@qq.com
Publikováno v:
Asian Agricultural Research. Aug2019, Vol. 11 Issue 8, p9-14. 6p.