Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Canping, Jiang"'
Autor:
Daniel J. Karst, Pieter J. Jacobs, Kevin Ramer, Fernie G. Mitchelson, Canping Jiang, Erik Heller Hughes
Publikováno v:
Biotechnology Progress. 36
Mammalian cells were grown to high density in a 3,000 L culture using perfusion with hollow fibers operated in a tangential flow filtration mode. The high-density culture was used to inoculate the production stage of a biomanufacturing process. At co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558ad366cc65904b65ffe73bd4f54648
https://doi.org/10.1002/btpr.3040
https://doi.org/10.1002/btpr.3040
Autor:
Canping, Jiang, Sarah, Scherfner, Lawrence W, Dick, David, Mahon, Difei, Qiu, Kuang-Chuan, Cheng, Abhinav A, Shukla
Publikováno v:
Biotechnology Progress. 27:442-450
The use of yeast- and plant-derived hydrolysates in cell culture production processes has sparked concerns over the potential immunogenicity risk posed by β-glucans and yeast peptides contained in these raw materials. This article utilizes a combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2d9049f1ce69f506ac3049192b708f
https://doi.org/10.1002/btpr.568
https://doi.org/10.1002/btpr.568
Publikováno v:
Biotechnology and Bioengineering. 108:59-68
Protein A chromatography is widely employed for the capture and purification of antibodies and Fc-fusion proteins. Due to the high cost of protein A resins, there is a significant economic driving force for using these chromatographic materials for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179003e927d72ef2e6b4ee9d09eee018
https://doi.org/10.1002/bit.22886
https://doi.org/10.1002/bit.22886
Publikováno v:
Journal of Chromatography A. 1216:5849-5855
A mechanistic study into Protein A chromatographic resin lifetime limitations is presented. Binding and mass transport properties of two widely used agarose-based Protein A resins were studied to distinguish between the roles of resin fouling due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5177df249a065fbdd87ac49e009b0bd4
https://doi.org/10.1016/j.chroma.2009.06.013
https://doi.org/10.1016/j.chroma.2009.06.013
Autor:
Susan Fugett Abu-Absi, Liying Yang, Canping Jiang, Abhinav A. Shukla, Sunitha Kandula, Bernhard M Schilling, Patrick Thompson
Publikováno v:
Biotechnology and bioengineering. 106(6)
The concept of design space has been taking root as a foundation of in-process control strategies for biopharmaceutical manufacturing processes. During mapping of the process design space, the multidimensional combination of operational variables is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bf2cef6b4d69ff598be9a4d981786f
https://pubmed.ncbi.nlm.nih.gov/20589669
https://pubmed.ncbi.nlm.nih.gov/20589669
Publikováno v:
Biotechnology progress. 24(3)
Residual host cell protein impurities (HCPs) are a key component of biopharmaceutical process related impurities. These impurities need to be effectively cleared through chromatographic steps in the downstream purification process to produce safe and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6136aa680f70ca0bb945229078fa2c08
https://pubmed.ncbi.nlm.nih.gov/18410156
https://pubmed.ncbi.nlm.nih.gov/18410156
Autor:
Canping Jiang, Ali Ozuer, James B. Wechuck, Joseph C. Glorioso, Soraya Pornsuwan, Fazard Pourarian, David Krisky, Mohammad M. Ataai
Publikováno v:
Biotechnology and bioengineering. 95(1)
Metal catalyzed oxidation (MCO), which typically involves oxygen free radical generation, is an important pathway that leads to the deterioration of many biological molecules in solution. The occurrence of MCO in immobilized metal affinity chromatogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31151eb467d4e09365ad2463a3bc7f5
https://pubmed.ncbi.nlm.nih.gov/16673413
https://pubmed.ncbi.nlm.nih.gov/16673413
Publikováno v:
Journal of chromatography. A. 1121(1)
We have recently shown that immobilized metal affinity chromatography (IMAC) is an effective technique for purification of herpes simplex virus type 1 (HSV-1) gene vector engineered to display cobalt affinity tag on the envelope. However, the tagged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23502b93b38ff264600506ea17deab4c
https://pubmed.ncbi.nlm.nih.gov/16735041
https://pubmed.ncbi.nlm.nih.gov/16735041
Publikováno v:
Biotechnology Progress; Jun2008, Vol. 24 Issue 3, p615-622, 8p