New approaches to modern statistical classification problems

Autor: Cannings, Timothy Ivor

This thesis concerns the development and mathematical analysis of statistical procedures for classification problems. In supervised classification, the practitioner is presented with the task of assigning an object to one of two or more classes, base

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.675908

Development and validation of DNA methylation scores in two European cohorts augment 10-year risk prediction of type 2 diabetes.

Autor: Cheng Y; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Gadd DA; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Gieger C; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, München-Neuherberg, Germany., Monterrubio-Gómez K; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Zhang Y; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Berta I; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Stam MJ; School of Informatics, University of Edinburgh, Edinburgh, UK., Szlachetka N; School of Informatics, University of Edinburgh, Edinburgh, UK., Lobzaev E; School of Informatics, University of Edinburgh, Edinburgh, UK., Wrobel N; Edinburgh Clinical Research Facility, University of Edinburgh, Western General Hospital, Edinburgh, UK., Murphy L; Edinburgh Clinical Research Facility, University of Edinburgh, Western General Hospital, Edinburgh, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Nangle C; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Walker RM; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, UK., Fawns-Ritchie C; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, München-Neuherberg, Germany.; German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance, München, Germany., Rathmann W; German Center for Diabetes Research, München-Neuherberg, Germany.; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Evans KL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., McIntosh AM; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Cannings TI; School of Mathematics, University of Edinburgh, Edinburgh, UK., Waldenberger M; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Ganna A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Vallejos CA; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. catalina.vallejos@ed.ac.uk.; The Alan Turing Institute, London, UK. catalina.vallejos@ed.ac.uk., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. riccardo.marioni@ed.ac.uk.

Publikováno v: Nature aging [Nat Aging] 2023 Apr; Vol. 3 (4), pp. 450-458. Date of Electronic Publication: 2023 Apr 06.