Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity.

Autor: Westcott PMK; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. westcott@cshl.edu.; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. westcott@cshl.edu., Muyas F; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, UK., Hauck H; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Smith OC; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Sacks NJ; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Ely ZA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Jaeger AM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Rideout WM 3rd; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Zhang D; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Bhutkar A; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Beytagh MC; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Canner DA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Jaramillo GC; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Bronson RT; Rodent Histopathology Core, Harvard Medical School, Boston, MA, USA., Naranjo S; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Jin A; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Patten JJ; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Cruz AM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Shanahan SL; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Cortes-Ciriano I; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, UK. icortes@ebi.ac.uk., Jacks T; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. tjacks@mit.edu.; Rodent Histopathology Core, Harvard Medical School, Boston, MA, USA. tjacks@mit.edu.

Publikováno v: Nature genetics [Nat Genet] 2023 Oct; Vol. 55 (10), pp. 1686-1695. Date of Electronic Publication: 2023 Sep 14.