Zobrazeno 1 - 10
of 766
pro vyhledávání: '"Cannabinoid receptor type 1"'
Autor:
Rodrigo Zamith Cunha, Giulia Salamanca, Fanny Mille, Cecilia Delprete, Cecilia Franciosi, Giuliano Piva, Alessandro Gramenzi, Roberto Chiocchetti
Publikováno v:
Animals, Vol 13, Iss 18, p 2833 (2023)
The endocannabinoid system (ECS) has emerged as a potential therapeutic target in veterinary medicine due to its involvement in a wide range of physiological processes including pain, inflammation, immune function, and neurological function. Modulati
Externí odkaz:
https://doaj.org/article/b23d874dff5e435eaceeff0b3b9de2ca
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 4, Pp 544-558 (2020)
Abstract Scope This study investigated whether AM251, a cannabinoid receptor type 1 (CB1) antagonist, ameliorates hepatic levels of metabolic abnormalities and inflammatory responses in a murine nonalcoholic steatohepatitis (NASH) model via reversal
Externí odkaz:
https://doaj.org/article/828adeb65eba4ef28c2e6950f0a487ae
Autor:
Myriam Dao, Helene François
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Chronic kidney disease (CKD) concerns millions of individuals worldwide, with few therapeutic strategies available to date. Recent evidence suggests that the endocannabinoid system (ECS) could be a new therapeutic target to prevent CKD. ECS combines
Externí odkaz:
https://doaj.org/article/5692fecb839243aabda017d02049571e
Autor:
Robin van Eenige, Zhixiong Ying, Lauren Tambyrajah, Amanda C.M. Pronk, Niek Blomberg, Martin Giera, Yanan Wang, Tamer Coskun, Mario van der Stelt, Patrick C.N. Rensen, Sander Kooijman
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100070- (2021)
Pharmacological blockade of the cannabinoid type 1 receptor, a G protein-coupled receptor expressed in the central nervous system and various peripheral tissues, reverses diet-induced obesity and dyslipidemia through the reduction of food intake and
Externí odkaz:
https://doaj.org/article/9dc750d1ebc14d54b6be276bd11ac14f
Autor:
Henrique Binda, Karina, Landau, Anne M, Chacur, Marucia, Brooks, David J, Cristiano Real, Caroline
Publikováno v:
Henrique Binda, K, Landau, A M, Chacur, M, Brooks, D J & Cristiano Real, C 2023, ' Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease ', Brain Research, vol. 1814, 148436 . https://doi.org/10.1016/j.brainres.2023.148436
Physical exercise benefits Parkinson's disease (PD) patients but the mechanism is unclear. Cannabinoid receptor type 1 (CB1R) is known to be reduced in PD patients and animal models. We test the hypothesis that binding of the CB1R inverse agonist, [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::fc450825f715f3a3aa7a006fc484b0c4
https://pure.au.dk/portal/da/publications/treadmill-exercise-modulates-nigral-and-hippocampal-cannabinoid-receptor-type-1-in-the-6ohda-model-of-parkinsons-disease(a9b83821-8136-41e6-a724-11fe7463413c).html
https://pure.au.dk/portal/da/publications/treadmill-exercise-modulates-nigral-and-hippocampal-cannabinoid-receptor-type-1-in-the-6ohda-model-of-parkinsons-disease(a9b83821-8136-41e6-a724-11fe7463413c).html
Autor:
Sun Mi Gu, Sowoon Seo, Daejin Park, Sanghyeon Kim, Santosh Lamichhane, Kyoung-Moon Han, Young-Hoon Kim, Sangmin Lee, Jin Tae Hong, Hye Jin Cha, Jaesuk Yun
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10486 (2021)
Interaction of cannabinoid receptor type 1 (CB1) and GABAergic neuronal activity is involved in drug abuse-related behavior. However, its role in drug-dependent Pavlovian conditioning is not well understood. In this study, we aimed to evaluate the ef
Externí odkaz:
https://doaj.org/article/268f8ed341814f318c30d00afd1fe04b
Autor:
Bo-Eun Kim, Byungyoon Choi, Woo-Ram Park, Yu-Ji Kim, In-Young Kim, Yoon Seok Jung, Yong-Hoon Kim, Chul-Ho Lee, Hueng-Sik Choi, Don-Kyu Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6021 (2021)
Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is an important transcription factor modulating gene transcription involved in endocrine control of liver metabolism. Transferrin receptor 2 (TFR2), a carrier protein for transferrin, is in
Externí odkaz:
https://doaj.org/article/816eb2442775430abb73a4255d838e77
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 5, Pp 2088-2101 (2017)
Background/Aims: Cannabinoids are vasoactive substances that act as key regulators of arterial tone in the blood vessels supplying peripheral tissues and the central nervous system. We therefore investigated the effect of cannabinoids on retinal capi
Externí odkaz:
https://doaj.org/article/2bdd26a602664e1e9ff8107a06b99b56
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