Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Canjun, Li"'
Autor:
Yu Wang, Wenqing Wang, Tao Zhang, Yin Yang, Jianyang Wang, Canjun Li, Xin Xu, Yuqi Wu, Ying Jiang, Jinghao Duan, Luhua Wang, Nan Bi
Publikováno v:
Journal of the National Cancer Center, Vol 4, Iss 2, Pp 177-187 (2024)
Background: Liquid biopsy-based biomarkers, including circulating tumor DNA (ctDNA) and blood tumor mutational burden (bTMB), are recognized as promising predictors of prognoses and responses to immune checkpoint inhibitors (ICIs), despite insufficie
Externí odkaz:
https://doaj.org/article/963f4f9165474b94b0a8daddc649c28d
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Cancer stem cells (CSCs) are a sub-population of cells possessing high tumorigenic potential, which contribute to therapeutic resistance, metastasis and recurrence. Eradication of CSCs is widely recognized as a crucial factor in improving pa
Externí odkaz:
https://doaj.org/article/48915092330243b2a68edbb901465a31
Autor:
Wenping Zeng, Canjun Li, Ruikun Wu, Xingguo Yang, Qingyan Wang, Bingqian Lin, Yanan Wei, Hao Li, Ge Shan, Lili Qu, Chunlei Cang
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002591 (2024)
Lysosomes are degradation centers of cells and intracellular hubs of signal transduction, nutrient sensing, and autophagy regulation. Dysfunction of lysosomes contributes to a variety of diseases, such as lysosomal storage diseases (LSDs) and neurode
Externí odkaz:
https://doaj.org/article/4fc368c6a08347b8bb46a1f0a6c9f0a9
Autor:
Yu Wang, Tao Zhang, Yin Yang, Jianyang Wang, Canjun Li, Xin Xu, Yuqi Wu, Ying Jiang, Jinghao Duan, Luhua Wang, Nan Bi
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/15b0882ac75d4b948bb99b25b1a05724
Autor:
Shana Li, Xiang Xu, Canjun Li, Ziyan Xu, Ke Wu, Qiong Ye, Yan Zhang, Xiaohua Jiang, Chunlei Cang, Changlin Tian, Jie Wen
Publikováno v:
NeuroImage, Vol 281, Iss , Pp 120374- (2023)
The study of neural circuits, which underlies perception, cognition, emotion, and behavior, is essential for understanding the mammalian brain, a complex organ consisting of billions of neurons. To study the structure and function of the brain, in vi
Externí odkaz:
https://doaj.org/article/f65f132889764146be997ee618cfcbda
Publikováno v:
Energy and Built Environment, Vol 3, Iss 1, Pp 113-127 (2022)
This study focuses on the development and analysis of a real-time updated operations strategy of a distributed energy system (DES). Owing to the relevant Chinese policy of electrical transmission and distribution, combined cooling, heating, and power
Externí odkaz:
https://doaj.org/article/677c3aa9140d416993120f607e893fd2
Autor:
Ruixiang Zhang, Canjun Li, Zhiyi Wan, Jianjun Qin, Yong Li, Zhen Wang, Qingfeng Zheng, Xiaozheng Kang, Xiankai Chen, Yun Li, Jie He, Yin Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionEsophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence, survival, and risk factors. Although the genomic characteristics of ESCC have been extensively characterized, the genomic differences between different geo
Externí odkaz:
https://doaj.org/article/86aa6cb775e44c86a5477aee60e97753
Autor:
Yu, Wang, Tao, Zhang, Yilin, Huang, Wei, Li, Jingjing, Zhao, Yin, Yang, Canjun, Li, Luhua, Wang, Nan, Bi
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:1154-1164
Consolidation durvalumab after chemoradiation therapy (CRT) has improved patient outcomes in stage III non-small cell lung cancer (NSCLC) since the practice-changing results of the PACIFIC trial, whereas real-world evidence regarding the PACIFIC regi
Autor:
Lili Qu, Bingqian Lin, Wenping Zeng, Chunhong Fan, Haotian Wu, Yushu Ge, Qianqian Li, Canjun Li, Yanan Wei, Jing Xin, Xingbing Wang, Dan Liu, Chunlei Cang
Publikováno v:
EMBO reports. 23
Autor:
Yayu Wang, Wenping Zeng, Bingqian Lin, Yichuan Yao, Canjun Li, Wenqi Hu, Haotian Wu, Jiamin Huang, Mei Zhang, Tian Xue, Dejian Ren, Lili Qu, Chunlei Cang
Publikováno v:
Science Advances
Description
The disease-associated protein CLN7 forms an organellar chloride channel and regulates lysosomal calcium signaling and function.
Neuronal ceroid lipofuscinoses (NCLs) are a group of autosomal recessive lysosomal storage diseases
The disease-associated protein CLN7 forms an organellar chloride channel and regulates lysosomal calcium signaling and function.
Neuronal ceroid lipofuscinoses (NCLs) are a group of autosomal recessive lysosomal storage diseases