Zobrazeno 1 - 10
of 5 174
pro vyhledávání: '"Canine model"'
Autor:
Emily D. Morales, Dongxin Wang, Matthew J. Burke, Jin Han, Drake D. Devine, Keqing Zhang, Dongsheng Duan
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Cytosolic calcium overload contributes to muscle degradation in Duchenne muscular dystrophy (DMD). The sarcoplasmic reticulum (SR) is the primary calcium storage organelle in muscle. The sarco-endoplasmic reticulum ATPase (SERCA)
Externí odkaz:
https://doaj.org/article/42fb4df068464dd18c06c51b7a99e1db
Autor:
Kasun Kodippili, Chady H. Hakim, Matthew J. Burke, Yongping Yue, James A. Teixeira, Keqing Zhang, Gang Yao, Gopal J. Babu, Roland W. Herzog, Dongsheng Duan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101268- (2024)
Excessive cytosolic calcium accumulation contributes to muscle degeneration in Duchenne muscular dystrophy (DMD). Sarco/endoplasmic reticulum calcium ATPase (SERCA) is a sarcoplasmic reticulum (SR) calcium pump that actively transports calcium from t
Externí odkaz:
https://doaj.org/article/8999a19b16ac45ccb94ac3fd43620ab2
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 574-581 (2023)
Introduction: Spinal cord injury (SCI) is associated with severe dysfunction of nervous tissue, and repair via the transplantation of bone marrow–derived mononuclear cells (BM-MNCs) into cerebrospinal fluid yields promising results. It is essential
Externí odkaz:
https://doaj.org/article/fcc1edf3673448499356f698b61784f4
Autor:
Benjamin Wilk, Haris Smailovic, Rebecca Sullivan, Erik R. Sistermans, John Butler, Hannah Jago, Michael Kovacs, Gerald Wisenberg, Jonathan D. Thiessen, Frank S. Prato
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background After myocardial infarction, fibrosis and an ongoing dysregulated inflammatory response have been shown to lead to adverse cardiac remodeling. FDG PET is an imaging modality sensitive to inflammation as long as suppression protoco
Externí odkaz:
https://doaj.org/article/2d4ef712cec94d168475b9a1309e76f5
Autor:
Emmanuelle Totain, Loïc Lindner, Nicolas Martin, Yolande Misseri, Alexandra Iché, Marie-Christine Birling, Tania Sorg, Yann Herault, Alain Bousquet-Melou, Pascale Bouillé, Christine Duthoit, Guillaume Pavlovic, Severine Boullier
Publikováno v:
Laboratory Animal Research, Vol 39, Iss 1, Pp 1-15 (2023)
Abstract Background Animal models are essential to understand the physiopathology of human diseases but also to evaluate new therapies. However, for several diseases there is no appropriate animal model, which complicates the development of effective
Externí odkaz:
https://doaj.org/article/d942d7339ede45d5b5ac1aac24e653db
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionBehavioural problems in family dogs are amongst the leading reasons for relinquishment to shelters which adversely affects animal welfare. Recent research suggests that certain problematic behavioural patterns might be analogous to human
Externí odkaz:
https://doaj.org/article/a1c5da1ad8d942ecb16ac2c778e9ea8a
Akademický článek
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Autor:
Yangfeng Xu, Kathelijne Peremans, Sofie Salden, Kurt Audenaert, Andre Dobbeleir, Ann Van Eeckhaut, Dimitri De Bundel, Jimmy H. Saunders, Chris Baeken
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
AimThe neurobiological effects of repetitive transcranial magnetic stimulation are believed to run in part through the dopaminergic system. Accelerated high frequency rTMS (aHF-rTMS), a new form of stimuli delivery, is currently being tested for its
Externí odkaz:
https://doaj.org/article/e034e39574cb40079b782952c7821444
Autor:
Zhengli Liu, Yuan Yuan, Rui Jiang, Boxiang Zhao, Jianping Gu, Xu He, Tao Wang, Yadong Shi, Yinghao Li, Yangyi Zhou, Guanqi Fu, Liang Chen, Maofeng Gong, Haobo Su, Jie Kong
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: The purpose of this research was to establish a safe, effective, and simple nervous system aneurysm model. This method could quickly and stably establish an exact canine tongue aneurysm model. This paper summarizes the technique and key p
Externí odkaz:
https://doaj.org/article/146e23be48d64cb98243151c0e0a2921
Publikováno v:
Royal Society Open Science, Vol 10, Iss 4 (2023)
The rising trend in non-communicable chronic inflammatory diseases coincides with changes in Western lifestyle. While changes in the human microbiota may play a central role in the development of chronic diseases, estimating the contribution of assoc
Externí odkaz:
https://doaj.org/article/e3d892496ee445baadb7c0398257ddb1