Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Canine Sarcoma"'
Autor:
Olivia Gourbault, Lola Llobat
Publikováno v:
Veterinary Sciences, Vol 7, Iss 4, p 146 (2020)
Sarcomas are frequent in dogs and canine species are excellent animal models for studying the human counterpart. However, osteosarcomas are a rare form of sarcoma with high death rates in humans and dogs. miRNAs are small endogenous RNAs that regulat
Externí odkaz:
https://doaj.org/article/37941a91062347acae0c6aa05cf4d4d5
Autor:
Michael Ziskind, Benoit Fatou, Emmanuel Bouchaert, Delphine Bertin, Nina Ogrinc, Yves-Marie Robin, Dominique Tierny, Cristian Focsa, Isabelle Fournier, Pierre-Damien Caux, Michel Salzet, Zoltan Takats
Publikováno v:
Clinical chemistry
Clinical chemistry, 2021, 67 (11), pp.1513-1523. ⟨10.1093/clinchem/hvab160⟩
Clinical chemistry, 2021, 67 (11), pp.1513-1523. ⟨10.1093/clinchem/hvab160⟩
Background Formalin-fixed paraffin-embedded (FFPE) tissue has been the gold standard for routine pathology for general and cancer postoperative diagnostics. Despite robust histopathology, immunohistochemistry, and molecular methods, accurate diagnosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397ebc67e8f284bd9b147fb04981a4d6
https://doi.org/10.1093/clinchem/hvab160
https://doi.org/10.1093/clinchem/hvab160
Autor:
Ali Khammanivong, Shee Kwan Phung, Erin B. Dickerson, Kathryn E. Dusenbery, Megan M. Duckett, Linh M. P. Nguyen, Jessica Lawrence
Publikováno v:
Veterinary and Comparative Oncology. 18:128-140
Adrenergic receptor (AR) expression has been demonstrated at several sites of primary and metastatic tumour growth and may influence proliferation, survival, metastasis and angiogenesis. AR antagonists like propranolol and carvedilol inhibit prolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64c0d04b96378cce8e7cfb9209c4ece
https://doi.org/10.1111/vco.12560
https://doi.org/10.1111/vco.12560
Autor:
Karan Kohli, R. Graeme Black, Kraig Abrams, Peter F Moore, Beverly Torok-Storb, Brett Schroeder, Mari Maeda-Whitaker, Stephen Gottschalk, Brian Hayes, Seth M. Pollack, Cassandra Miller, Bernard Séguin, Shihong Zhang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Chimeric antigen receptor (CAR) T cell therapy has transformed therapy for hematological malignancies but has not yet been established as standard of care for any solid tumors. One obstacle for human solid tumor immunotherapy research is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25121e1657d998cae74641a504780b21
https://doi.org/10.1136/jitc-2020-sitc2020.0139
https://doi.org/10.1136/jitc-2020-sitc2020.0139
Autor:
Luke Anthony Wittenburg, Dayn Romero Godinez, Anuradha Illendula, Fernando Alegre, John H. Bushweller, Amanda R. Ormonde
Publikováno v:
Veterinary and comparative oncology, vol 18, iss 1
Vet Comp Oncol
Vet Comp Oncol
Osteosarcoma remains the most common primary bone tumour in dogs with half of affected dogs unable to survive 1 year beyond diagnosis. New therapeutic options are needed to improve outcomes for this disease. Recent investigations into potential thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa74d9a9b8cba4212d04c0a2578ab680
https://escholarship.org/uc/item/9d12k3xr
https://escholarship.org/uc/item/9d12k3xr
Autor:
Andrew Chen, Anabel Bergeron, Derek Butterwick, Joel Werier, John C. Bell, Hesham Abdelbary, Jovian Tsang, Mohammed Selman, Nicole E. Forbes, Jean-Simon Diallo, Hwan Hee Son, Fabrice Le Boeuf, Rozanne Arulanandam, Fanny Tzelepis
Publikováno v:
International Journal of Cancer. 141:1257-1264
The poor prognosis of patients with advanced bone and soft-tissue sarcoma has not changed in the past several decades, highlighting the necessity for new therapeutic approaches. Immunotherapies, including oncolytic viral (OV) therapy, have shown grea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a4af64467d4667feab2aea663cac49
https://doi.org/10.1002/ijc.30813
https://doi.org/10.1002/ijc.30813
Autor:
Jillian Zientek Walz, Anthony E. Rizzardi, Joseph S. Koopmeiners, Amber L. Winter, Matthew Breen, Colleen L. Forster, Jaime F. Modiano, Antonella Borgatti, Kathleen Stuebner, Jong Hyuk Kim, Deborah A. Todhunter, Daniel A. Vallera, Michael S. Henson, Stephen C. Schmechel, Jerry W. Froelich, Jonathan Henriksen, Felix Oh, Kristy Pilbeam, Aaron L. Sarver, Kerstin Lindblad-Toh
Publikováno v:
Molecular Cancer Therapeutics. 16:956-965
Sarcomas differ from carcinomas in their mesenchymal origin. Therapeutic advancements have come slowly, so alternative drugs and models are urgently needed. These studies report a new drug for sarcomas that simultaneously targets both tumor and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c502a21f17b4cf1ec595ea339842a3
https://doi.org/10.1158/1535-7163.mct-16-0637
https://doi.org/10.1158/1535-7163.mct-16-0637
Autor:
Klaus Holzmann, Martin Reifinger, Luke B. Borst, Marlene L. Hauck, Miriam Kleiter, Sandra Sampl, Abigail J. Deloria, Theresa Kreilmeier, Ingrid Walter
Publikováno v:
Molecular Carcinogenesis. 56:923-935
Alternative lengthening of telomeres (ALT) is a telomere maintenance mechanism (TMM) found in some human tumors such as sarcomas. Canine tumors are not characterized for ALT and the study aim was to identify if the ALT phenotype exists in canine sarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c811f9ac0993a45e00a7cefd658f7b6
https://doi.org/10.1002/mc.22546
https://doi.org/10.1002/mc.22546
Akademický článek
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Autor:
Matsuyama, Arata
Metronomic chemotherapy is a unique low dose chemotherapeutic approach that affects pro-angiogenic and immunosuppressive characteristics of cancer. Induction of apoptosis in activated vascular endothelial cells and regulatory T cells in cancer patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______453::bc6fea3aba902b1fb42ebc49871c59f3
https://hdl.handle.net/10214/26386
https://hdl.handle.net/10214/26386