Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Canine Leukemia"'
Autor:
Daniel M. Rotroff, Steven E. Suter, Dorothee Bienzle, Joshua D. Schiffman, Anne C. Avery, Sarah C. Roode, Alison A. Motsinger-Reif, Matthew Breen
Publikováno v:
Chromosome Research. 23:681-708
Leukemia in dogs is a heterogeneous disease with survival ranging from days to years, depending on the subtype. Strides have been made in both human and canine leukemia to improve classification and understanding of pathogenesis through immunophenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb46b2865cd2f6eb8517a6e47fbf3b
https://doi.org/10.1007/s10577-015-9475-7
https://doi.org/10.1007/s10577-015-9475-7
Autor:
Giantin, M, Aresu, L, Aricò, A, Gelain, Me, Riondato, Fulvio, Martini, V, Comazzi, S, Dacasto, M., Aresu, Luca
Publikováno v:
Veterinary Immunology and Immunopathology. 152:325-332
The tyrosine-kinase receptor c-KIT (c-KIT) plays an important role in proliferation, survival and differentiation of progenitor cells in normal hematopoietic cells. In human hematological malignancies, c-KIT is mostly expressed by progenitor cell neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49239dd265c75b0d0488e2dafc38f83
https://doi.org/10.1016/j.vetimm.2013.01.003
https://doi.org/10.1016/j.vetimm.2013.01.003
Publikováno v:
Research in veterinary science. 114
Methotrexate is an antimetabolite used in the treatment of cancer and non-malignant diseases including rheumatoid arthritis, psoriasis and graft vs. host disease. Combination therapy with methotrexate was successful in the treatment of canine lymphom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b54010cf042469997d72d765766f448
https://pubmed.ncbi.nlm.nih.gov/28992489
https://pubmed.ncbi.nlm.nih.gov/28992489
Publikováno v:
Experimental Hematology. 39:124-132
Objective Leukemia-initiating cells (LICs) have been the subject of considerable investigation because of their ability to self-renew and maintain leukemia. Thus, selective targeting and killing of LICs would provide highly efficient and novel therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7a8ed19702c33f75a63916bddbcce5
https://doi.org/10.1016/j.exphem.2010.09.012
https://doi.org/10.1016/j.exphem.2010.09.012
Publikováno v:
Veterinary Clinical Pathology. 39:169-179
Background: Classification of leukemias requires specialized diagnostic techniques. Automated preliminary indicators of neoplastic cells in blood would expedite selection of appropriate tests. Objective: The objective of this study was to assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d10ed2c9f72f24509bf31b167cddf889
https://doi.org/10.1111/j.1939-165x.2010.00214.x
https://doi.org/10.1111/j.1939-165x.2010.00214.x
Autor:
Brenda M. Sandmaier, Laura J. Peterson, Erlinda B. Santos, George E. Sale, Hans-Peter Kiem, Xiao-Bing Zhang, Brian C. Beard, Monica S. Thakar
Publikováno v:
Experimental Hematology. 37:1157-1166
Objective There are currently no large animal models to study the biology of leukemia and development of novel antileukemia therapies. We have previously shown that dogs transplanted with homeobox B4 (HOXB4)−transduced autologous CD34 + cells devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306e7182253d84bc9ee60680ddff0ac7
https://doi.org/10.1016/j.exphem.2009.07.004
https://doi.org/10.1016/j.exphem.2009.07.004
Publikováno v:
Research in Veterinary Science. 74:101-104
DNA methylation is an epigenetic modification in which a methyl group is added usually to the fifth carbon position of a cytosine residue. Dysregulation of this process is an important molecular event which has been shown to be associated with neopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925efb0e0d6b244908a024c96bff06d9
https://doi.org/10.1016/s0034-5288(02)00179-0
https://doi.org/10.1016/s0034-5288(02)00179-0
Autor:
Mauro Dacasto, Fulvio Riondato, Maria Elena Gelain, Stefano Comazzi, Valeria Martini, Luca Aresu, A. Poggi, Mery Giantin, Arianna Aricò
Publikováno v:
Veterinary immunology and immunopathology. 159(1-2)
Hyaluronan receptor CD44 mediates interaction between cells and extracellular matrix. The expression of standard form and its variants is dysregulated in human leukemias and is associated with metastasis and prognosis. The aim of this work is the eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d1f9b6c4baa1f51b1ce5e0b6287992
https://pubmed.ncbi.nlm.nih.gov/24629892
https://pubmed.ncbi.nlm.nih.gov/24629892