Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Cangzhi Jia"'
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 9, Pp 15809-15829 (2023)
Transcription factors (TFs) are important factors that regulate gene expression. Revealing the mechanism affecting the binding specificity of TFs is the key to understanding gene regulation. Most of the previous studies focus on TF-DNA binding sites
Externí odkaz:
https://doaj.org/article/80b8b9b797594baf8e24b15451563d15
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 4, Pp 6853-6865 (2023)
Phasic small interfering RNAs are plant secondary small interference RNAs that typically generated by the convergence of miRNAs and polyadenylated mRNAs. A growing number of studies have shown that miRNA-initiated phasiRNA plays crucial roles in regu
Externí odkaz:
https://doaj.org/article/19930bcf399344758805e4777c408df3
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 12, Pp 13294-13305 (2022)
Regulatory elements in DNA sequences, such as promoters, enhancers, terminators and so on, are essential for gene expression in physiological and pathological processes. A promoter is the specific DNA sequence that is located upstream of the coding g
Externí odkaz:
https://doaj.org/article/51e28cd1bf474f0a87ce9ecf4560db9f
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Neuropeptides contain more chemical information than other classical neurotransmitters and have multiple receptor recognition sites. These characteristics allow neuropeptides to have a correspondingly higher selectivity for nerve receptors and fewer
Externí odkaz:
https://doaj.org/article/02890004027c4ec199b3aa9ed3c8d4ce
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 1, Pp 775-791 (2022)
As one of the most significant protein post-translational modifications (PTMs) in eukaryotes, ubiquitylation plays an essential role in regulating diverse cellular functions, such as apoptosis, cell division, DNA repair and replication, intracellular
Externí odkaz:
https://doaj.org/article/2c51fd0518264d959563d0e41e4026d7
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1027-1034 (2021)
5-Methylcytosine (m5C) is an important post-transcriptional modification that has been extensively found in multiple types of RNAs. Many studies have shown that m5C plays vital roles in many biological functions, such as RNA structure stability and m
Externí odkaz:
https://doaj.org/article/fe37bc8b0df64cc9a029d9a3d5db274f
An Interpretable Prediction Model for Identifying N7-Methylguanosine Sites Based on XGBoost and SHAP
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 362-372 (2020)
Recent studies have increasingly shown that the chemical modification of mRNA plays an important role in the regulation of gene expression. N7-methylguanosine (m7G) is a type of positively-charged mRNA modification that plays an essential role for ef
Externí odkaz:
https://doaj.org/article/b88ebc03cd9f4c4abd6a5e6023d07a29
Publikováno v:
IEEE Access, Vol 8, Pp 79376-79382 (2020)
Pseudouridine (Ψ) is the most prevalent RNA modification, which is formed from uridine through an isomerization reaction. With the increasing availability of genomic and proteomic samples, computer-aided pseudouridine-synthase-specific Ψ site recog
Externí odkaz:
https://doaj.org/article/b2eae27ccb2e43789aa4b6233f3d6596
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 6, Pp 10410-10423 (2014)
Protein S-nitrosylation is a reversible post-translational modification by covalent modification on the thiol group of cysteine residues by nitric oxide. Growing evidence shows that protein S-nitrosylation plays an important role in normal cellular f
Externí odkaz:
https://doaj.org/article/fd16cfe3f19c4cb2b29435d282ea77b5
Publikováno v:
Molecules, Vol 23, Iss 12, p 3097 (2018)
With the in-depth study of posttranslational modification sites, protein ubiquitination has become the key problem to study the molecular mechanism of posttranslational modification. Pupylation is a widely used process in which a prokaryotic ubiquiti
Externí odkaz:
https://doaj.org/article/9f1e16490298461a9570090668de1913