Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Cangang Zhang"'
Autor:
Lina Sun, Anjun Jiao, Haiyan Liu, Renyi Ding, Ning Yuan, Biao Yang, Cangang Zhang, Xiaoxuan Jia, Gang Wang, Yanhong Su, Dan Zhang, Lin Shi, Chenming Sun, Aijun Zhang, Lianjun Zhang, Baojun Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract CD8+ T cell immune responses are regulated by multi-layer networks, while the post-translational regulation remains largely unknown. Transmembrane ectodomain shedding is an important post-translational process orchestrating receptor expressi
Externí odkaz:
https://doaj.org/article/339a44187cf844aaa26210a704658a26
Autor:
Shengkun Peng, Anqi Lin, Aimin Jiang, Cangang Zhang, Jian Zhang, Quan Cheng, Peng Luo, Yifeng Bai
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive CTLs biomarkers remain elusive, as cytotoxicity-molecule expre
Externí odkaz:
https://doaj.org/article/96dffe7c77344b3a81f5b751168894a0
Autor:
Yu Li, Cangang Zhang, Aimin Jiang, Anqi Lin, Zaoqu Liu, Xiangshu Cheng, Wanting Wang, Quan Cheng, Jian Zhang, Ting Wei, Peng Luo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Regulatory T cells (Tregs) expressing the transcription factor FoxP3 are essential for maintaining immunological balance and are a significant component of the immunosuppressive tumor microenvironment (TME). Single-cell RNA sequencing (ScRNA
Externí odkaz:
https://doaj.org/article/0969a67385d1447fb44c110f9066da10
Autor:
Chenfeng Han, Minmin Ge, Pengfei Xing, Tian Xia, Cangang Zhang, Kaili Ma, Yifu Ma, Shicheng Li, Wenhui Li, Xiaowei Liu, Baojun Zhang, Liyuan Zhang, Lianjun Zhang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-13 (2024)
Abstract Cancer cells develop multiple strategies to evade T cell-mediated killing. On one hand, cancer cells may preferentially rely on certain amino acids for rapid growth and metastasis. On the other hand, sufficient nutrient availability and upta
Externí odkaz:
https://doaj.org/article/93f2d9c74fd6466b8e1a853bbafc19e7
Autor:
Anjun Jiao, Cangang Zhang, Xin Wang, Lina Sun, Haiyan Liu, Yanhong Su, Lei Lei, Wenhua Li, Renyi Ding, Chenguang Ding, Meng Dou, Puxun Tian, Chenming Sun, Xiaofeng Yang, Lianjun Zhang, Baojun Zhang
Publikováno v:
Journal of Advanced Research, Vol 55, Iss , Pp 73-87 (2024)
Introduction: Both innate and adaptive immune system undergo evolution from low to high vertebrates. Due to the limitation of conventional approaches in identifying broader spectrum of immune cells and molecules from various vertebrates, it remains u
Externí odkaz:
https://doaj.org/article/e7629e4595814b6eaa16fbf5c1e2238b
Autor:
Lihaoyun Huang, Haitao Li, Cangang Zhang, Quan Chen, Zaoqu Liu, Jian Zhang, Peng Luo, Ting Wei
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract As single‐cell RNA sequencing enables the detailed clustering of T‐cell subpopulations and facilitates the analysis of T‐cell metabolic states and metabolite dynamics, it has gained prominence as the preferred tool for understanding he
Externí odkaz:
https://doaj.org/article/8d994ec639da49faa21703fda8ba5de4
Autor:
Xin Wang, Lina Sun, Biao Yang, Wenhua Li, Cangang Zhang, Xiaofeng Yang, Yae Sun, Xiaonan Shen, Yang Gao, Bomiao Ju, Yafeng Gao, Dan Liu, Jiapeng Song, Xiaoxuan Jia, Yanhong Su, Anjun Jiao, Haiyan Liu, Lianjun Zhang, Lan He, Lei Lei, WanJun Chen, Baojun Zhang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Regulatory T cells (Tregs) are instrumental in maintaining immune tolerance and preventing destructive autoimmunity, but how heterogeneous Treg populations are established remains largely unknown. Here, we show that Zfp335 deletion in Tregs failed to
Externí odkaz:
https://doaj.org/article/f5956165413941d0840303ca8158b71a
Autor:
Xue Yang, Chen Zong, Chao Feng, Cangang Zhang, Artem Smirnov, Gangqi Sun, Changchun Shao, Luyao Zhang, Xiaojuan Hou, Wenting Liu, Yan Meng, Liying Zhang, Changshun Shao, Lixin Wei, Gerry Melino, Yufang Shi
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Aging is always accompanied by chronic diseases which probably attribute to long‐term chronic inflammation in the aging body. Whereas, the mechanism of chronic inflammation in aging body is still obscure. Mesenchymal stem cells (MSCs) are
Externí odkaz:
https://doaj.org/article/17da3cf683604bf5a7d791e33c39d452
Autor:
Liying Liu, Yanan Xie, Hong Yang, Anqi Lin, Minjun Dong, Haitao Wang, Cangang Zhang, Zaoqu Liu, Quan Cheng, Jian Zhang, Shuofeng Yuan, Peng Luo
Publikováno v:
iMeta, Vol 2, Iss 3, Pp n/a-n/a (2023)
Abstract The tumor immune microenvironment (TIME) is closely associated with tumor formation, particularly linked to the human papillomavirus (HPV), and regulates tumor initiation, proliferation, infiltration, and metastasis. With the rise of immunot
Externí odkaz:
https://doaj.org/article/d0efea7abb6643ae9207d3afd517e73e
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2220-2242 (2021)
Proteases have a fundamental role in maintaining physiological homeostasis, but their dysregulation results in severe activity imbalance and pathological conditions, including cancer onset, progression, invasion, and metastasis. This striking importa
Externí odkaz:
https://doaj.org/article/17360848adfe46bfa4b0eba7a8616308