Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells

Autor: Holley RJ, Tai G, Williamson AJK, Taylor S, Cain SA, Richardson SR, Merry CLR, Whetton AD, Kielty CM, Canfield AE

Mesenchymal progenitor cells have great therapeutic potential, yet incomplete characterisation of their cell surface interface limits their clinical exploitation. We have employed subcellular fractionation with quantitative discovery proteomics to de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2295::a1f9a70445f4dc4411952e6e55ed2456

FTI-277 inhibits smooth muscle cell calcification by up-regulating PI3K/Akt signaling and inhibiting apoptosis.

Autor: Ponnusamy A; Vascular Research Group, Salford Royal NHS Foundation Trust, Salford, United Kingdom.; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Sinha S; Vascular Research Group, Salford Royal NHS Foundation Trust, Salford, United Kingdom.; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Hyde GD; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Borland SJ; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Taylor RF; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Pond E; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Eyre HJ; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Inkson CA; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Gilmore A; Division of Cancer Studies & Wellcome Trust Centre for Cell-Matrix Research, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Ashton N; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Kalra PA; Vascular Research Group, Salford Royal NHS Foundation Trust, Salford, United Kingdom.; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom., Canfield AE; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom.

Publikováno v: PloS one [PLoS One] 2018 Apr 24; Vol. 13 (4), pp. e0196232. Date of Electronic Publication: 2018 Apr 24 (Print Publication: 2018).

Contribution of VCAF-positive cells to neovascularization and calcification in atherosclerotic plaque development.

Autor: Wilkinson, FL, Liu, Y, Rucka, AK, Jeziorska, M, Hoyland, JA, Heagerty, AM, Canfield, AE, Alexander, MY

Publikováno v: Journal of Pathology; Feb2007, Vol. 211 Issue 3, p362-369, 8p

Pericyte Dysfunction Contributes to Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats.

Autor: Siyang Lin¹, Landon, Benjamin¹, Hongxia Zhang², Kunlin Jin¹ kunlin.jin@unthsc.edu

Publikováno v: Aging & Disease. Jun2024, Vol. 15 Issue 3, p1357-1372. 16p.

Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signalling and cross-talk with TGFβ.

Autor: Borland SJ; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; Stem Cell Glycobiology Group, School of Materials, University of Manchester, Manchester, UK., Morris TG; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Borland SC; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Morgan MR; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Francis SE; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Merry CLR; Stem Cell Glycobiology Group, School of Materials, University of Manchester, Manchester, UK.; Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK., Canfield AE; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2017 Nov 01; Vol. 113 (13), pp. 1639-1652.