Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Caner Çağlar"'
Autor:
Jean-Laurent Casanova, A. Nazli Basak, David Neil Cooper, Jungmin Choi, M Ece Kars, Peter D. Stenson, Hakan Buluş, Robin Palvadeau, Alper Yavuz, Caner Çağlar, O Emre Onat, Kaya Bilguvar, Tayfun Ozcelik, Yuval Itan, Murat Gunel, Jeffrey M. Friedman
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
The construction of population-based variomes has contributed substantially to our understanding of the genetic basis of human inherited disease. Here, we investigated the genetic structure of Turkey from 3,362 unrelated subjects whose whole exomes (
Autor:
Caner Çağlar, Jeffrey M. Friedman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We set out to identify novel neuronal populations controlling feeding behaviors. Therefore, we focused on identifying novel neuronal populations modulating food intake and body weight. In this article, we report that DMHPpp1r17 neurons a
Autor:
Zhiying Li, Keith Tan, Estefania P. Azevedo, Luca Parolari, Alexander R. Nectow, Caner Çağlar, Jeffrey M. Friedman, Ana Domingos, Marc Schneeberger
Publikováno v:
Molecular Metabolism, Vol 13, Iss, Pp 83-89 (2018)
Molecular Metabolism
Molecular Metabolism
Objectives Melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus (LH) regulate food intake and body weight, glucose metabolism and convey the reward value of sucrose. In this report, we set out to establish the respective roles of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a21583b730672c91632275f8f078fc
http://hdl.handle.net/20.500.12645/29113
http://hdl.handle.net/20.500.12645/29113
Autor:
Victoria E. Clark, Murat Gunel, Jie Li, Ketu Mishra-Gorur, Geneive Carrión-Grant, Caner Çağlar, Mehmet Bakırcıoğlu, S. Bulent Omay, Koray Özduman, Akdes Serin Harmanci, Octavian Henegariu, E. Zeynep Erson-Omay, Lisa M. DeAngelis, Alexander O. Vortmeyer, Jennifer Moliterno, M. Necmettin Pamir, Joachim M. Baehring, Katsuhito Yasuno, Viviane Tabar, Mark W. Youngblood, Kaya Bilguvar
Publikováno v:
Genome Medicine
Background Glioblastoma multiforme (GBM) constitutes nearly half of all malignant brain tumors and has a median survival of 15 months. The standard treatment for these lesions includes maximal resection, radiotherapy, and chemotherapy; however, indiv
Autor:
Kevin P. Campbell, Jiri Vajsar, Murat Gunel, Mariam Almuriekhi, Rasim Ozgur Rosti, Maha S. Zaki, Jumana Y. Al-Aama, Damir Musaev, Caner Çağlar, Joseph G. Gleeson, Kaya Bilguvar, Tobias Willer, Jennifer L. Silhavy, Beate Albrecht, Gonul Ogur, Esra Dikoglu, Rami Abou Jamra, Tawfeg Ben-Omran, Ahmet Okay Caglayan, Julie Jerber
Jamra, Rami Abou/0000-0002-1542-1399; caglar, caner/0000-0002-5857-757X; Zaki, Maha/0000-0001-7840-0002; Caglayan, Ahmet/0000-0002-2332-322X; Campbell, Kevin/0000-0003-2066-5889 WOS: 000387529600015 PubMed: 27773428 Cobblestone lissencephaly (COB) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770505fe747fdd174f65acd84d7d4658
http://hdl.handle.net/20.500.12645/29114
http://hdl.handle.net/20.500.12645/29114
Autor:
Ketu Mishra-Gorur, S. Bulent Omay, Kaya Bilguvar, Alexander O. Vortmeyer, Akdes Serin Harmanci, Süleyman Coşkun, Jia Sun, Tanyeri Barak, Mehmet Bakırcıoğlu, Ahmet Okay Caglayan, Victoria E. Clark, Koray Özduman, Jie Li, M. Necmettin Pamir, Nikolaus Schultz, Anita Huttner, Nils Weinhold, Jennifer Moliterno Günel, Murat Gunel, Doğan Köse, Chris Sander, Katsuhito Yasuno, Yavuz Köksal, Burçin Baran, Jacob F Baranoski, E. Zeynep Erson-Omay, Caner Çağlar, Geneive Carrión-Grant
WOS: 000364783100007
PubMed: 25740784
Background. Malignant high-grade gliomas (HGGs), including the most aggressive form, glioblastoma multiforme, show significant clinical and genomic heterogeneity. Despite recent advances, the overall su
PubMed: 25740784
Background. Malignant high-grade gliomas (HGGs), including the most aggressive form, glioblastoma multiforme, show significant clinical and genomic heterogeneity. Despite recent advances, the overall su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d90624c511df9741dd5e005f8378622
https://avesis.deu.edu.tr/publication/details/52a7b7d2-6625-4e5c-94be-fd818db55416/oai
https://avesis.deu.edu.tr/publication/details/52a7b7d2-6625-4e5c-94be-fd818db55416/oai
Autor:
Sinan Çomu, Hudson H. Freeze, Gozde Tugce Akgumus, Ketu Mishra-Gorur, Ahmet Okay Caglayan, Akdes Serin Harmanci, Murat Gunel, Jacob F Baranoski, Katsuhito Yasuno, Duygu Dölen, Emine Z. Erson-Omay, Caner Çağlar, Kaya Bilguvar, Hande Kaymakçalan, Yesim Parman
N-glycanase 1 (NGLY1) is a conserved enzyme that is responsible for the deglycosylation of misfolded N-glycosylated proteins in the cytoplasm prior to their proteasome-mediated degradation. Disruption of this degradation process has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56412f106cd6f80a326f05ba957696b
http://hdl.handle.net/20.500.12645/29115
http://hdl.handle.net/20.500.12645/29115
Autor:
Wengi Han, Katsuhito Yasuno, Bulent Guclu, Ahmet Okay Caglayan, Murat Gunel, Barış Ekici, Phillip B. Murray, Beyhan Tüysüz, Yildirim Bayezit Sakalar, Hüseyin Çaksen, Hande Kaymakçalan, Senem Senturk, Mehmet Bakırcıoğlu, Nihat Demir, Kaya Bilguvar, Fesih Aktar, Ebru Guzel, Caner Çağlar, Oğuz Tuncer, Gozde Tugce Akgumus, Jacob F Baranoski, Nenad Sestan, Frank J. Minja, Berrin Aktekin, Aslan Guzel, Emine Z. Erson-Omay
BACKGROUND: Knobloch syndrome is a rare, autosomal recessive, developmental disorder characterized by stereotyped ocular abnormalities with or without occipital skull deformities (encephalocele, bone defects, and cutis aplasia). Although there is cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42d739dc56740eec78aa9cc986cd9c7
https://avesis.yyu.edu.tr/publication/details/37458afa-fdb6-45fd-b7ce-00b11a385eec/oai
https://avesis.yyu.edu.tr/publication/details/37458afa-fdb6-45fd-b7ce-00b11a385eec/oai
Autor:
Jana Schroth, William B. Dobyns, Hülya Kayserili, Jean-Baptiste Rivière, Haig Keshishian, Murat Gunel, Katsuhito Yasuno, Neil C. Chi, Shrikant Mane, Duygu Dölen, Burçin Baran, Richard P. Lifton, Caner Çağlar, Ahmet Okay Caglayan, Heba A.A. Hossni, Hüseyin Per, Ashleigh E. Schaffer, E. Zeynep Erson-Omay, Octavian Henegariu, Sefer Kumandaş, Cengiz Dilber, Fernando Vonhoff, Chiswili Chabu, Jacob F Baranoski, Wenqi Han, Kaya Bilguvar, Tian Xu, Gozde Tugce Akgumus, Rasim Ozgur Rosti, Hakan Gümüş, Shu Tu, Ketu Mishra-Gorur, Sayoko Nishimura, Emily Spencer, Nenad Sestan, Frank J. Minja, Joseph G. Gleeson, Maha S. Zaki, Çağri Çağlar, Angeliki Louvi
SummaryExome sequencing analysis of over 2,000 children with complex malformations of cortical development identified five independent (four homozygous and one compound heterozygous) deleterious mutations in KATNB1, encoding the regulatory subunit of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa601c2692c65701d6fcc4dcbef7d0f9
http://hdl.handle.net/20.500.12645/29101
http://hdl.handle.net/20.500.12645/29101
Autor:
Marc Schneeberger, Keith Tan, Alexander R. Nectow, Luca Parolari, Caner Caglar, Estefania Azevedo, Zhiying Li, Ana Domingos, Jeffrey M. Friedman
Publikováno v:
Molecular Metabolism, Vol 13, Iss , Pp 83-89 (2018)
Objectives: Melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus (LH) regulate food intake and body weight, glucose metabolism and convey the reward value of sucrose. In this report, we set out to establish the respective roles of
Externí odkaz:
https://doaj.org/article/17b818d3d7b9489f8af10e6d97acf6ff