Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Candy, Greczylo"'
Autor:
Julio Chirinos, Patricio Lopez-Jaramillo, Evangelos Giamarellos-Bourboulis, Gonzalo Dávila-del-Carpio, Abdul Bizri, Jaime Andrade-Villanueva, Oday Salman, Carlos Cure-Cure, Nelson Rosado-Santander, Mario Cornejo Giraldo, Luz González-Hernández, Rima Moghnieh, Rapti Angeliki, María Cruz Saldarriaga, Marcos Pariona, Carola Medina, Ioannis Dimitroulis, Charalambos Vlachopoulos, Corina Gutierrez, Juan Rodriguez-Mori, Edgar Gomez-Laiton, Rosa Pereyra, Jorge Ravelo Hernández, Hugo Arbañil, José Accini-Mendoza, Maritza Pérez-Mayorga, Haralampos Milionis, Garyfallia Poulakou, Gregorio Sánchez, Renzo Valdivia-Vega, Mirko Villavicencio-Carranza, Ricardo Ayala-Garcia, Carlos Castro-Callirgos, Rosa Alfaro Carrasco, Willy Lecca Danos, Tiffany Sharkoski, Katherine Greene, Bianca Pourmussa, Candy Greczylo, Jesse Chittams, Paraskevi Katsaounou, Zoi Alexiou, Styliani Sympardi, Nancy Sweitzer, Mary Putt, Jordana Cohen
Background Abnormal cellular lipid metabolism appears to underlie SARS-CoV-2 cytotoxicity and may involve inhibition of peroxisome proliferator activated receptor alpha (PPARα). Fenofibrate, a PPAR-α activator, modulates cellular lipid metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6251da34088b9d7ee7bed26c7bd590a5
https://doi.org/10.21203/rs.3.rs-1933913/v1
https://doi.org/10.21203/rs.3.rs-1933913/v1
Autor:
Julio A, Chirinos, Patricio, Lopez-Jaramillo, Evangelos J, Giamarellos-Bourboulis, Gonzalo H, Dávila-Del-Carpio, Abdul Rahman, Bizri, Jaime F, Andrade-Villanueva, Oday, Salman, Carlos, Cure-Cure, Nelson R, Rosado-Santander, Mario P, Cornejo Giraldo, Luz A, González-Hernández, Rima, Moghnieh, Rapti, Angeliki, María E, Cruz Saldarriaga, Marcos, Pariona, Carola, Medina, Ioannis, Dimitroulis, Charalambos, Vlachopoulos, Corina, Gutierrez, Juan E, Rodriguez-Mori, Edgar, Gomez-Laiton, Rosa, Cotrina Pereyra, Jorge Luis, Ravelo Hernández, Hugo, Arbañil, José, Accini-Mendoza, Maritza, Pérez-Mayorga, Charalampos, Milionis, Garyfallia, Poulakou, Gregorio, Sánchez, Renzo, Valdivia-Vega, Mirko, Villavicencio-Carranza, Ricardo J, Ayala-García, Carlos A, Castro-Callirgos, Rosa M, Alfaro Carrasco, Willy, Garrido Lecca Danos, Tiffany, Sharkoski, Katherine, Greene, Bianca, Pourmussa, Candy, Greczylo, Juan, Ortega-Legaspi, Douglas, Jacoby, Jesse, Chittams, Paraskevi, Katsaounou, Zoi, Alexiou, Styliani, Sympardi, Nancy K, Sweitzer, Mary, Putt, Jordana B, Cohen, Pedro Antonio, Segura-Saldaña
Publikováno v:
Nature metabolism. 4(12)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cytotoxicity may involve inhibition of peroxisome proliferator-activated receptor alpha. Fenofibrate activates peroxisome proliferator-activated receptor alpha and inhibits SARS-CoV-2 repli