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Akademický článek

Combined lung and liver transplant for cirrhosis, idiopathic pulmonary fibrosis, and hemophilia A: Case report

Autor: Lorenzo Olivero, Hong Liang, Ian A. Makey, Si M. Pham, Jorge Sinclair, Stephen Aniskevich, III, Sadia Z. Shah, Dana K. Perry, Wesley L. Allen, Nathan H. Waldron, Liu Yang, Pramod K. Guru, Candido E. Rivera, Pablo Moreno Franco, Tathagat Narula

Publikováno v: Transplantation Reports, Vol 9, Iss 4, Pp 100163- (2024)

Combined lung and liver transplantation (CLLT) is a rare intervention for end-stage lung and liver diseases. It poses a challenge for patients with increased bleeding risk due to Hemophilia A and liver coagulopathy. We present the first documented ca

Externí odkaz: https://doaj.org/article/aff861885b1d42a2bc9b6416fa9eb061

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Akademický článek

Real-world experience with ponatinib therapy in chronic phase chronic myeloid leukemia: impact of depth of response on survival and prior exposure to nilotinib on arterial occlusive events

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)

Abstract We surveyed the performance of ponatinib, as salvage therapy, in a real-world setting of chronic phase chronic myeloid leukemia (CML-CP). Among 55 consecutive patients (median age 49 years) with relapsed/refractory CML-CP, 35 (64%) had faile

Externí odkaz: https://doaj.org/article/5713a85908654b83ae61bd72a1efa7e7

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Akademický článek

Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis

Autor: Emily B. Wolf MD, David Li MD, Andre J. Fernandez MPAS, PA-C, Lindsay B. Gardner MD, Candido E. Rivera MD, Ewa M. Wysokinska MD, Marwan E. Shaikh MD, Han W. Tun MD, Vivek Roy MD, Muhamad Alhaj Moustafa MD

Publikováno v: Journal of Investigative Medicine High Impact Case Reports, Vol 11 (2023)

Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic

Externí odkaz: https://doaj.org/article/128a25ad03e74b48badd6609083a9599

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Akademický článek

Deep vein thrombosis in the setting of Klippel-Trenaunay syndrome and sirolimus treatment

Autor: Susana Fortich, MD, Charles Ritchie, MD, Marwan E. Shaikh, MD, Beau Toskich, MD, Candido E. Rivera, MD, Young Erben, MD

Publikováno v: Journal of Vascular Surgery Cases and Innovative Techniques, Vol 7, Iss 3, Pp 524-528 (2021)

Klippel-Trenaunay syndrome (KTS) is a congenital vascular disorder characterized by the triad of cutaneous capillary malformation, lymphatic and venous anomalies, and soft tissue and bone overgrowth. Sirolimus is a mechanistic target of rapamycin inh

Externí odkaz: https://doaj.org/article/7d48e6dbd4d14fa9ad0e977f4f02291c

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Akademický článek

A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis

Autor: Vikas Gupta, Ruben A. Mesa, Michael W.N. Deininger, Candido E. Rivera, Shireen Sirhan, Carrie Baker Brachmann, Helen Collins, Jun Kawashima, Yan Xin, Srdan Verstovsek

Publikováno v: Haematologica, Vol 102, Iss 1 (2017)

Momelotinib, a small-molecule inhibitor of Janus kinase 1 and Janus kinase 2, has demonstrated efficacy in myelofibrosis patients with 300 mg, once-daily dosing. This open-label, non-randomized, phase 1/2 study evaluated the safety and therapeutic be

Externí odkaz: https://doaj.org/article/dd14288ed0fb42e0b8e4c3c38537c4b5

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