Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Candice Poux"'
Autor:
Peter Järver, Aleksandra Dondalska, Candice Poux, AnnSofi Sandberg, Joseph Bergenstråhle, Annette E. Sköld, Nathalie Dereuddre-Bosquet, Fréderic Martinon, Sandra Pålsson, Eman Zaghloul, David Brodin, Birgitta Sander, Kim A. Lennox, Mark A. Behlke, Samir EL-Andaloussi, Janne Lehtiö, Joakim Lundeberg, Roger LeGrand, Anna-Lena Spetz
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Recognition of nucleic acids by endosomal Toll-like receptors (TLR) is essential to combat pathogens, but requires strict control to limit inflammatory responses. The mechanisms governing this tight regulation are unclear. We found that sing
Externí odkaz:
https://doaj.org/article/8ee60f6cd9e941b7b20a1654b77636dc
Autor:
Candice Poux, Aleksandra Dondalska, Joseph Bergenstråhle, Sandra Pålsson, Vanessa Contreras, Claudia Arasa, Peter Järver, Jan Albert, David C. Busse, Roger LeGrand, Joakim Lundeberg, John S. Tregoning, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The initiation of an immune response is dependent on the activation and maturation of dendritic cells after sensing pathogen associated molecular patterns by pattern recognition receptors. However, the response needs to be balanced as excessive pro-i
Externí odkaz:
https://doaj.org/article/15ac5559956a41ec8c1585cb51e3c25a
Autor:
Lucille Adam, Moisés López-González, Albin Björk, Sandra Pålsson, Candice Poux, Marie Wahren-Herlenius, Carmen Fernández, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Early clearance of tuberculosis is the successful eradication of inhaled bacteria before the development of an adaptive immune response. We previously showed, by utilizing a non-virulent mycobacteria infection model, that C57BL/6 mice are more effici
Externí odkaz:
https://doaj.org/article/d33f949e64b148c9bbb94dc2fe9b5c09
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2018, 145 (24), pp.dev166850. ⟨10.1242/dev.166850⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (24), pp.dev166850. ⟨10.1242/dev.166850⟩
Hedgehog (Hh) is a conserved morphogen that controls cell differentiation and tissue patterning in metazoans. In Drosophila, the Hh signal is transduced from the G protein-coupled receptor Smoothened (Smo) to the cytoplasmic Hh signaling complex (HSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241ae33a4e353a1ac1a6eecce0a60c58
https://hal.archives-ouvertes.fr/hal-02403182
https://hal.archives-ouvertes.fr/hal-02403182
Autor:
Bernard Malissen, Maelíosa T.C. McCrudden, Ultan F. Power, Rebecca J. Ingram, Marija Zaric, Adrien Kissenpfennig, Christopher J. Scott, Ryan F. Donnelly, Mary L. Hanna, Candice Poux, Oksana Lyubomska
Publikováno v:
Zaric, M, Lyubomska, O, Poux, C, Hanna, M L, McCrudden, M T, Malissen, B, Ingram, R J, Power, U, Scott, C J, Donnelly, R F & Kissenpfennig, A 2015, ' Dissolving Microneedle Delivery of Nanoparticle Encapsulated Antigen Elicits Efficient Cross-Priming and Th1 Immune Responses by Murine Langerhans Cells ', Journal of investigative dermatology, vol. 135, pp. 425–434 . https://doi.org/10.1038/jid.2014.415
Dendritic cells (DCs) of the skin play an important role in skin-mediated immunity capable of promoting potent immune responses. We availed of polymeric dissolving microneedle (MN) arrays laden with nano-encapsulated antigen to specifically target sk
Autor:
Candice Poux, Jacques Banchereau, Lucille Adam, Catherine Chapon, Anne-Laure Flamar, Sandra Zurawski, Yves Levy, Frédéric Martinon, Gabrielle Romain, Pierre Rosenbaum, Nina Salabert, Sangkon Oh, Nathalie Dereuddre-Bosquet, Olivier Epaulard, Roger Le Grand, Gerard Zurawski
Publikováno v:
Journal of Immunology
Journal of Immunology, 2014, 193 (5), pp.2416-2426. ⟨10.4049/jimmunol.1303339⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 193 (5), pp.2416-2426. ⟨10.4049/jimmunol.1303339⟩
Journal of Immunology, 2014, 193 (5), pp.2416-2426. ⟨10.4049/jimmunol.1303339⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 193 (5), pp.2416-2426. ⟨10.4049/jimmunol.1303339⟩
Dendritic cells are major APCs that can efficiently prime immune responses. However, the roles of skin-resident Langerhans cells (LCs) in eliciting immune responses have not been fully understood. In this study, we demonstrate for the first time, to
Autor:
Olivier Touzelet, Ultan F. Power, Sandrine Henri, Adrien Kissenpfennig, Christopher J. Scott, Sharifah Al-Zahrani, Bernard Malissen, Oksana Lyubomska, Leah E. Wallace, Marija Zaric, Dorothea Terhorst, Francois Fay, Ryan F. Donnelly, Candice Poux
Publikováno v:
ACS Nano
The efficacious delivery of antigens to antigen-presenting cells (APCs), in particular, to dendritic cells (DCs), and their subsequent activation remains a significant challenge in the development of effective vaccines. This study highlights the pote