Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Candice I Snyders"'
Serum and cerebrospinal fluid host proteins indicate stroke in children with tuberculous meningitis.
Autor:
Charles M Manyelo, Novel N Chegou, James A Seddon, Candice I Snyders, Hygon Mutavhatsindi, Portia M Manngo, Gerhard Walzl, Kim Stanley, Regan S Solomons
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250944 (2021)
IntroductionStroke is a common complication in children with tuberculous meningitis (TBM). Host proteins may give us insight into the mechanisms of stroke in TBM and serve as biomarkers for detection of stroke, however, they have not been widely expl
Externí odkaz:
https://doaj.org/article/a742ba5451b64bcb83bb927ce3772d44
Autor:
Melissa Murphy, Sara Suliman, Libby Briel, Helen Veldtsman, Nondumiso Khomba, Hadn Africa, Marcia Steyn, Candice I. Snyders, Ilana C. van Rensburg, Gerhard Walzl, Novel N. Chegou, Mark Hatherill, Willem A. Hanekom, Thomas J. Scriba, Elisa Nemes
Publikováno v:
International Journal of Infectious Diseases, Vol 130, Iss , Pp S52-S62 (2023)
Objectives: The bacille Calmette-Guérin (BCG) vaccine is usually administered at birth to protect against severe forms of tuberculosis in children. BCG also confers some protection against other infections, possibly mediated by innate immune trainin
Externí odkaz:
https://doaj.org/article/8534b02c1bcf4e559287bfdff91c0299
Autor:
Bih H. Chendi, Candice I. Snyders, Kristian Tonby, Synne Jenum, Martin Kidd, Gerhard Walzl, Novel N. Chegou, Anne M. Dyrhol-Riise
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background: Several host inflammatory markers have been proposed as biomarkers for diagnosis and treatment response in Tuberculosis (TB), but few studies compare their utility in different demographic, ethnic, and TB endemic settings.Methods: Fifty-f
Externí odkaz:
https://doaj.org/article/6c0616c0d01040d389a3889e8c181c7f
Autor:
Charles M, Manyelo, Regan S, Solomons, Candice I, Snyders, Martin, Kidd, Yajna, Kooblal, Vinzeigh N, Leukes, Conita, Claassen, Kelly, Roos, Kim, Stanley, Gerhard, Walzl, Novel N, Chegou
Publikováno v:
Biomarkers. 27:549-561
Autor:
Charles M. Manyelo, Regan S. Solomons, Candice I. Snyders, Portia M. Manngo, Hygon Mutavhatsindi, Belinda Kriel, Kim Stanley, Gerhard Walzl, Novel N. Chegou
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Background. The diagnosis of tuberculous meningitis (TBM) especially in children is challenging. New tests are urgently needed for the diagnosis of the disease, especially in resource-limited settings. Methods. We collected cerebrospinal fluid (CSF)
Externí odkaz:
https://doaj.org/article/f3317bce325142ba8b34eef234c8e54d
Autor:
Andrea Gutschmidt, Candice I. Snyders, Dannielle K Moore, Gina Leisching, Ilana C. van Rensburg, Andre G. Loxton
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 8, Iss 3, Pp 458-467 (2020)
Immunity, Inflammation and Disease, Vol 8, Iss 3, Pp 458-467 (2020)
Introduction B‐cells are essential in the defense against Mycobacterium tuberculosis. Studies on isolated cells may not accurately reflect the responses that occur in vivo due to the presence of other cells. This study elucidated the influence of m
Autor:
Susanne Dam Nielsen, Kristian Tonby, Candice I. Snyders, Anne Ma Dyrhol-Riise, Synne Jenum, Novel N. Chegou, Malene Hove-Skovsgaard, Hallgeir Tveiten, Bih H. Chendi, Gerhard Walzl
Publikováno v:
Chendi, B H, Tveiten, H, Snyders, C, Tonby, K, Jenum, S, Nielsen, S D, Hove-Skovsgaard, M, Walzl, G, Chegou, N N & Dyrhol-Riise, A M 2021, ' CCL1 and IL-2Ra differentiate Tuberculosis disease from latent infection Irrespective of HIV infection in low TB burden countries ', Journal of Infection, vol. 83, no. 4, pp. 433-443 . https://doi.org/10.1016/j.jinf.2021.07.036
Objectives: To evaluate the performance of selected host immunological biomarkers in differentiating tuberculosis (TB) disease from latent TB infection (LTBI) in HIV uninfected and infected individuals enrolled in TB low-burden countries.Design: Part
Autor:
Shirley McAnda, Gerhard Walzl, Martin Kidd, Candice I. Snyders, Stephanus T. Malherbe, Petri Ahlers, Andriëtte Hiemstra, Nonjabulo S. Makhoba, Andrea Gutschmidt, Novel N. Chegou, Charles M. Manyelo, Kim Stanley, Portia M. Manngo, Hygon Mutavhatsindi
Publikováno v:
J Infect
Summary Background There is an urgent need for new tools for the diagnosis of TB. We evaluated the usefulness recently described host biomarkers in supernatants from the newest generation of the QuantiFERON test (QuantiFERON Plus) as tools for the di
Autor:
Hygon Mutavhatsindi, James A Seddon, Candice I. Snyders, Charles M. Manyelo, Kim Stanley, Regan Solomons, Novel N. Chegou, Gerhard Walzl, Portia M. Manngo
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250944 (2021)
PLoS ONE
PLoS ONE
Introduction Stroke is a common complication in children with tuberculous meningitis (TBM). Host proteins may give us insight into the mechanisms of stroke in TBM and serve as biomarkers for detection of stroke, however, they have not been widely exp
Autor:
Ilana C. van Rensburg, Hadn Africa, Gerhard Walzl, Mark Hatherill, Candice I. Snyders, Nondumiso Khomba, Sara Suliman, Novel N. Chegou, Marcia Steyn, Helen Veldtsman, Willem A. Hanekom, Melissa Murphy, Libby Briel, Thomas J. Scriba, Elisa Nemes
Publikováno v:
SSRN Electronic Journal.
Infants are highly susceptible to disease caused by infection with intracellular pathogens, such as Mycobacterium tuberculosis. The Bacille Calmette-Guerin (BCG) vaccine is usually administered at birth to protect against severe forms of tuberculosis