Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Candice Contet"'
Autor:
Mahum T. Siddiqi, Dhruba Podder, Amanda R. Pahng, Alexandria C. Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J. Roberts, Scott Edwards, Marisa Roberto, Florence P. Varodayan
Publikováno v:
Addiction Neuroscience, Vol 9, Iss , Pp 100137- (2023)
Alcohol use disorder (AUD) produces cognitive deficits, indicating a shift in prefrontal cortex (PFC) function. PFC glutamate neurotransmission is mostly mediated by α-amino-3‑hydroxy-5-methyl-4-isoxazolepropionic acid-type ionotropic receptors (A
Externí odkaz:
https://doaj.org/article/06eb8a910c9d45f59ac89c917ba77f9d
Autor:
Agbonlahor Okhuarobo, Jessica L. Bolton, Ighodaro Igbe, Eric P. Zorrilla, Tallie Z. Baram, Candice Contet
Publikováno v:
Neurobiology of Stress, Vol 13, Iss , Pp 100269- (2020)
Childhood adversity increases vulnerability to alcohol use disorders and preclinical models are needed to investigate the underlying neurobiological mechanisms. The present study modeled early-life adversity by rearing male and female C57BL/6J mouse
Externí odkaz:
https://doaj.org/article/f7b43133f4b74727bcb44756234d5698
Autor:
Ami Cohen, Timothy W Whitfield, Max Kreifeldt, Pascale Koebel, Brigitte L Kieffer, Candice Contet, Olivier George, George F Koob
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97216 (2014)
Dynorphins, endogenous opioid peptides that arise from the precursor protein prodynorphin (Pdyn), are hypothesized to be involved in the regulation of mood states and the neuroplasticity associated with addiction. The current study tested the hypothe
Externí odkaz:
https://doaj.org/article/e28f081ec6f24fdfadda5d8b288c6214
Autor:
Giovana C. Macedo, Max Kreifeldt, Scott P. Goulding, Agbonlahor Okhuarobo, Harpreet Sidhu, Candice Contet
Publikováno v:
Neuropsychopharmacology. 48:821-830
Alcohol use disorders can be driven by negative reinforcement. Alterations of the microtubule cytoskeleton have been associated with mood regulation in the context of depression. Notably, MAP4343, a pregnenolone derivative known to promote tubulin as
Autor:
Agbonlahor Okhuarobo, Maggie Angelo, Jessica L. Bolton, Catherine Lopez, Ighodaro Igbe, Tallie Z. Baram, Candice Contet
Publikováno v:
Alcohol: Clinical and Experimental Research. 47:336-347
Stressful early-life experiences increase the risk of developing an alcohol use disorder. We had previously found that male C57BL/6J mice reared under limited bedding and nesting (LBN) conditions, a model of early-life adversity, escalate their ethan
Autor:
Max Kreifeldt, Melissa A. Herman, Harpreet Sidhu, Agbonlahor Okhuarobo, Giovana C. Macedo, Roxana Shahryari, Pauravi J. Gandhi, Marisa Roberto, Candice Contet
Publikováno v:
Molecular Psychiatry. 27:2502-2513
Corticotropin-releasing factor (CRF) signaling in the central nucleus of the amygdala (CeA) plays a critical role in rodent models of excessive alcohol drinking. However, the source of CRF acting in the CeA during alcohol withdrawal remains to be ide
Autor:
Jeffery L Dunning, Catherine Lopez, Colton Krull, Max Kreifeldt, Maggie Angelo, Charu Ramakrishnan, Karl Deisseroth, Candice Contet
The parasubthalamic nucleus (PSTN) is responsive to refeeding after food deprivation and PSTN subpopulations can suppress feeding. However, no study directly addressed the role of PSTN neurons activated upon food access resumption. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c193550ee5a9ef8f453ea7d83e7376
https://doi.org/10.1101/2023.01.28.525750
https://doi.org/10.1101/2023.01.28.525750
Publikováno v:
Alcohol. 109:69
Autor:
Jeffery L. Dunning, Max Kreifeldt, Agbonlahor Okhuarobo, Catherine Lopez, Colton Krull, Maggie Angelo, Maya Mehta, Tanvi Shah, Candice Contet
Publikováno v:
Alcohol. 109:88
Publikováno v:
Neuropharmacology
The parasubthalamic nucleus (PSTN), a small nucleus located on the lateral edge of the posterior hypothalamus, has emerged in recent years as a highly interconnected node within the network of brain regions sensing and regulating autonomic function a