Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Candice A. Shaifer"'
Autor:
Kevin P. Becker, John D. Hainsworth, Tarek Mekhail, David Wright, Howard A. Burris, Sajeel A. Chowdhary, Janice Faulkner Eakle, Kimberly West-Osterfield, Gilbert Darin Anthony Padula, Mythili Shastry, Meredith Scarberry, Kent C. Shih, Robert M. Langdon, Candice A. Shaifer, Kathleen Yost
Publikováno v:
Journal of Neuro-Oncology. 144:303-311
Current bevacizumab-based regimens have failed to improve survival in patients with recurrent glioblastoma. To improve treatment efficacy, we evaluated bevacizumab + BKM120, an oral pan-class I PI3K inhibitor, in this patient population. A brief phas
Publikováno v:
International Journal of Cancer. 127:2063-2075
Glioblastoma multiforme (GBM) remains the most devastating neoplasm of the central nervous system and has a dismal prognosis. Ionizing radiation represents an effective therapy for GBM, but radiotherapy remains only palliative because of radioresista