Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Candace K Mathiason"'
Autor:
Joseph A Westrich, Erin E McNulty, Molly Carpenter, Mollie Burton, Kirsten Reed, Amy Nalls, Audrey Sandoval, Christie Mayo, Candace K Mathiason
Publikováno v:
Virus Research, Vol 338, Iss , Pp 199246- (2023)
Bluetongue virus (BTV) is an economically important pathogen of ruminant species with worldwide prevalence. While many BTV infections are asymptomatic, animals with symptomatic presentation deteriorate quickly with the sickest succumbing to disease w
Externí odkaz:
https://doaj.org/article/a1aa33b3d5ab445380b7ad09e6564ba0
Autor:
Davin M Henderson, Nathaniel D Denkers, Clare E Hoover, Erin E McNulty, Sarah K Cooper, Lauren A Bracchi, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228327 (2020)
Chronic wasting disease (CWD) continues to spread or be recognized in the United States, Canada, and Europe. CWD is diagnosed by demonstration of the causative misfolded prion protein (PrPCWD) in either brain or lymphoid tissue using immunodetection
Externí odkaz:
https://doaj.org/article/fee6c1e1f1704280a3563561e88077b1
Autor:
Joanne M Tennant, Manci Li, Davin M Henderson, Margaret L Tyer, Nathaniel D Denkers, Nicholas J Haley, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0227094 (2020)
CWD is an emergent prion disease that now affects cervid species on three continents. CWD is efficiently spread in wild and captive populations, likely through both direct animal contact and environmental contamination. Here, by longitudinally assayi
Externí odkaz:
https://doaj.org/article/aba7d3cdedda4f67a9a0b0beab69ef84
Autor:
Nathaniel D Denkers, Clare E Hoover, Kristen A Davenport, Davin M Henderson, Erin E McNulty, Amy V Nalls, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237410 (2020)
The minimum infectious dose required to induce CWD infection in cervids remains unknown, as does whether peripherally shed prions and/or multiple low dose exposures are important factors in CWD transmission. With the goal of better understand CWD inf
Externí odkaz:
https://doaj.org/article/cca47ac598124311849de7ecbf8bb64c
Autor:
Sarah K Cooper, Clare E Hoover, Davin M Henderson, Nicholas J Haley, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221654 (2019)
The diagnosis of chronic wasting disease (CWD) relies on demonstration of the disease-associated misfolded CWD prion protein (PrPCWD) in brain or retropharyngeal lymph node tissue by immunodetection methods, e.g. ELISA and immunohistochemistry (IHC).
Externí odkaz:
https://doaj.org/article/bf4290ff7f0149f4b517066f4f00a542
Autor:
Erin McNulty, Amy V Nalls, Samuel Mellentine, Erin Hughes, Laura Pulscher, Edward A Hoover, Candace K Mathiason
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216621 (2019)
Longitudinal studies of chronic wasting disease (CWD) in the native host have provided considerable understanding of how this prion disease continues to efficiently spread among cervid species. These studies entail great cost in animal, time and fina
Externí odkaz:
https://doaj.org/article/64b6df70a6b54b9d85e9b99ef32f9d3b
Autor:
Ronald A Shikiya, Katie A Langenfeld, Thomas E Eckland, Jonathan Trinh, Sara A M Holec, Candace K Mathiason, Anthony E Kincaid, Jason C Bartz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006298 (2017)
Prion strains are characterized by strain-specific differences in neuropathology but can also differ in incubation period, clinical disease, host-range and tissue tropism. The hyper (HY) and drowsy (DY) strains of hamster-adapted transmissible mink e
Externí odkaz:
https://doaj.org/article/e2f53bb9ab9647d6b2611c6fdd8ae575
Autor:
Kristen A Davenport, Clare E Hoover, Jifeng Bian, Glenn C Telling, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183927 (2017)
The agent responsible for prion diseases is a misfolded form of a normal protein (PrPC). The prion hypothesis stipulates that PrPC must be present for the disease to manifest. Cervid populations across the world are infected with chronic wasting dise
Externí odkaz:
https://doaj.org/article/d80f7c37160f48099f78dc9baf5883ca
Autor:
Candace K Mathiason
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005249 (2015)
Externí odkaz:
https://doaj.org/article/ce4690e06428404184b73fc44d588a6e
Autor:
Alan M Elder, Davin M Henderson, Amy V Nalls, Jason M Wilham, Byron W Caughey, Edward A Hoover, Anthony E Kincaid, Jason C Bartz, Candace K Mathiason
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80203 (2013)
Blood-borne transmission of infectious prions during the symptomatic and asymptomatic stages of disease occurs for both human and animal transmissible spongiform encephalopathies (TSEs). The geographical distribution of the cervid TSE, chronic wastin
Externí odkaz:
https://doaj.org/article/8927ea0d72c7491d982e67ab5015856b