Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Candace Chi"'
Autor:
George Zhou, Yunchan Chen, Candace Chien, Leslie Revatta, Jannatul Ferdous, Michelle Chen, Shourov Deb, Sol De Leon Cruz, Alan Wang, Benjamin Lee, Mert R. Sabuncu, William Browne, Herrick Wun, Bobak Mosadegh
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract For hemodialysis patients, arteriovenous fistula (AVF) patency determines whether adequate hemofiltration can be achieved, and directly influences clinical outcomes. Here, we report the development and performance of a deep learning model fo
Externí odkaz:
https://doaj.org/article/6e8fdb3e06ce4b32b03620b5aa7b25a3
Autor:
Fabien Vincent, Michelle Dourado, Daniel Emerling, Luna Liu, Victor Yip, Margaret Nguyen, Zhi-Liang Wei, Zipfel Sheila, Candace Chi, Amy Gustafson, Jeff DeFalco, Michael G. Kelly, John Kincaid, Qingling Zhang, Donogh J R O'Mahony, Matthew A.J. Duncton, Alejandra Acevedo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:4011-4015
Antagonists of the TRPV4 receptor were identified using a focused screen, followed by a limited optimization program. The leading compounds obtained from this exercise, RN-1665 23 and RN-9893 26, showed moderate oral bioavailability when dosed to rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53256b218e4196c4d5f87c151a03f04
https://doi.org/10.1016/j.bmcl.2015.06.098
https://doi.org/10.1016/j.bmcl.2015.06.098
Publikováno v:
Developmental Biology. 353(1):120-133
The super-phylum Lophotrochozoa contains the plurality of extant animal phyla and exhibits a corresponding diversity of adult body plans. Moreover, in contrast to Ecdysozoa and Deuterostomia, most lophotrochozoans exhibit a conserved pattern of stere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc29a4783b5d445510007e113fe5e112
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-21 (2022)
Abstract Background The application of machine learning to cardiac auscultation has the potential to improve the accuracy and efficiency of both routine and point-of-care screenings. The use of convolutional neural networks (CNN) on heart sound spect
Externí odkaz:
https://doaj.org/article/c2d2bbcbdce34c8e8637fde98b63c60c
Autor:
Michael G. Kelly, Daniel Emerling, Jeff DeFalco, Margaret Nguyen, Candace Chi, Carl Kaub, Fabien Vincent, Matthew A.J. Duncton, John Kincaid, Sumithra Gowlugari
Publikováno v:
MedChemComm. 3:1258
Fatty acid amide hydrolase (FAAH) inhibition is a promising target for the treatment of pain, anxiety and depression. The vast majority of FAAH inhibitors contain an electrophilic moiety and are known to react covalently with the enzyme. Herein we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60cc26005526f0e154b74ab12cf98d16
https://doi.org/10.1039/c2md20146a
https://doi.org/10.1039/c2md20146a