Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Candace C. McCombs"'
Autor:
Jane M. Olson, C. F. McCarthy, Robert C. Elston, Candace C. McCombs, Fiona M. Stevens, Fei Zhong, Joseph P. Michalski
Publikováno v:
Nature Genetics. 14:329-333
Celiac disease is a strongly heritable gastrointestinal illness that is an especially important model of the genetically complex multifactorial immune mediated diseases. The HLA component of celiac disease (a specific HLA-DQ heterodimer)is largely es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d36f02f9522aebefd8a45a2afeb0604
https://doi.org/10.1038/ng1196-329
https://doi.org/10.1038/ng1196-329
Autor:
Joseph P. Michalski, R. C. Elston, T. Arai, T. Cao, C. F. McCarthy, Candace C. McCombs, Fiona M. Stevens
Publikováno v:
Tissue Antigens. 47:127-133
Celiac disease (CD) has one of the strongest class II HLA associations of any human illness. We used DNA-RFLP typing to study the class II HLA genotypes of celiac disease patients from the West of Ireland, the geographic area with the highest rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777a67e77f478b490fd710a7d412cca1
https://doi.org/10.1111/j.1399-0039.1996.tb02525.x
https://doi.org/10.1111/j.1399-0039.1996.tb02525.x
Publikováno v:
The American Journal of the Medical Sciences. 307:204-211
Celiac disease is a fascinating illness, from both a clinical and research perspective. Most clinicians consider a diagnosis of celiac disease when a young patient has classic signs and symptoms of steatorrhea and severe malabsorption. However, the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263d2ca3cdb7a66c8c8e20e1f1866122
https://doi.org/10.1097/00000441-199403000-00007
https://doi.org/10.1097/00000441-199403000-00007
Autor:
Jaime L. Hernández, Joseph P. Michalski, Candace C. McCombs, Ciaran F. McCarthy, Fiona M. Stevens, Robert C. Elston, G. P. Vogler, D. C. Rao
Publikováno v:
Genetic Epidemiology. 8:13-27
Although coeliac disease (CD) is strongly associated with the HLA alleles B8 and DR3, the genetic basis of this illness remains obscure. Recent studies show that at least two unlinked loci are involved. Most studies agree on recessivity at the HLA-un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5972140a5cd0533cfeeac56e79ab6205
https://doi.org/10.1002/gepi.1370080103
https://doi.org/10.1002/gepi.1370080103
Publikováno v:
The Journal of Immunology. 120:532-537
Human peripheral blood mononuclear cells which are precultured in tissue culture medium containing 5% fetal calf serum (FCS) have markedly augmented reactivity to a suboptimal concentration of phytohemagglutinin (PHA). The augmentation of response is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77c93449c09204e81312430f77d5e9e8
https://doi.org/10.4049/jimmunol.120.2.532
https://doi.org/10.4049/jimmunol.120.2.532
Autor:
Harry Walter, Timothy J. Webber, Joseph P. Michalski, Candace C. McCombs, Bernard J. Moncla, Eugene J. Krob, Linda L. Graham
Publikováno v:
The Journal of Immunology. 123:1687-1695
Partitioning of cells in dextran-poly(ethylene glycol) aqueous-aqueous two-phase systems is a sensitive method for separating cells and for obtaining information on their surface properties. Highly purified lymphocytes were obtained by velocity sedim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2394e7079ef761d565915d3b6edf0d3
https://doi.org/10.4049/jimmunol.123.4.1687
https://doi.org/10.4049/jimmunol.123.4.1687
Publikováno v:
Arthritis & Rheumatism. 29:586-591
Alpha 1-antitrypsin is a glycoprotein that functions as the major protease inhibitor in human serum. Many genetic variants of alpha 1-antitrypsin can be detected by electrophoretic techniques. We used isoelectric focusing on ultrathin gels to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de872fd65fbf1119fc2c3a163510a4cd
https://doi.org/10.1002/art.1780290502
https://doi.org/10.1002/art.1780290502
Autor:
Julie Botvin Madorsky, Candace C. McCombs, Edward A. Collacott, Jon M. Larson, Joseph P. Michalski, D. Eltorai
Publikováno v:
Rheumatology. 20:193-197
The histocompatibility antigen HLA-B27 was determined in 43 patients with post-traumatic spinal cord injury (SCI). The prevalence of B27 was significantly increased in the SCI patients with ectopic ossification. Five of 21 patients with ectopic bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a9d9519b95a1b037dc74808a5c5dca
https://doi.org/10.1093/rheumatology/20.4.193
https://doi.org/10.1093/rheumatology/20.4.193
Publikováno v:
Clinical Immunology and Immunopathology. 29:15-28
Partitioning in a two-polymer aqueous phase system was used to probe the surface properties of lymphoid cell subpopulations in aged male NZB/NZW F1 hybrid (B/W) mice, an important model of autoimmunity, immunodeficiency, and lymphoid malignancy. Sple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a0a288b4d63bebf8763ab57b442ca7
https://doi.org/10.1016/0090-1229(83)90003-x
https://doi.org/10.1016/0090-1229(83)90003-x
Publikováno v:
Journal of Immunological Methods. 83:101-112
Alpha-1-antitrypsin (alpha 1AT) is the major protease inhibitor in human serum, and plays an important role protecting tissues from potentially harmful enzymes released during inflammatory reactions. Proteolytic enzymes such as leukocyte elastase are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e395152de4d0014dd4820282db887fb6
https://doi.org/10.1016/0022-1759(85)90063-8
https://doi.org/10.1016/0022-1759(85)90063-8