Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Candace B. Pert"'
Autor:
Jiadai Liu, Yusaku Yoshioka, Mami Noda, Daichi Tomonaga, Michael R. Ruff, Candace B. Pert, Kota Kitazono, Richard Kinkead, Jean-Philippe Rousseau
Publikováno v:
Neurochemistry International. 119:184-189
Chemokine signaling is important in neuropathic pain, with microglial cells expressing chemokine (C-C motif) receptor CCR2, CCR5 and CCR8, all playing key roles. In the previous report (Padi et al., 2012), oral administration of a short peptide, RAP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e57a224c40d614e9329ceb2350e89c
https://doi.org/10.1016/j.neuint.2017.12.005
https://doi.org/10.1016/j.neuint.2017.12.005
Autor:
Dominique Schols, Stefano Aquaro, Michael R. Ruff, Carlo Federico Perno, Maria T. Polianova, Candace B. Pert, Michela Pollicita, Alessandro Ranazzi
Publikováno v:
Antiviral Chemistry and Chemotherapy. 18:285-295
Monocytes/macrophages (M/M) are strategic reservoirs of HIV-1, spreading the virus to other cells and inducing apoptosis in T-lymphocytes, astrocytes and neurons. M/M are commonly infected by R5 HIV-1 strains, which use the chemokine receptor CCR5. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706855d2f0474e218001102781e9371c
https://doi.org/10.1177/095632020701800504
https://doi.org/10.1177/095632020701800504
Publikováno v:
Neuroscience. 134:671-676
Chronic neuroinflammation plays a prominent role in the progression of Alzheimer's disease. Reactive microglia and astrocytes are observed within the hippocampus during the early stages of the disease. Epidemiological findings suggest that anti-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3136392c7f3070cb309f11287254ff9
https://doi.org/10.1016/j.neuroscience.2005.04.029
https://doi.org/10.1016/j.neuroscience.2005.04.029
Autor:
Gifford Leoung, Michael R. Ruff, Candace B. Pert, Quan-en Yang, Francis W. Ruscetti, Maria T. Polianova
Publikováno v:
Current HIV Research. 1:51-67
Peptide T, named for its high threonine content (ASTTTNYT), was derived by a database search which assumed that a relevant receptor binding epitope within env (gp120) would have sequence homology to a known signaling peptide. Binding of radiolabeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c7cd106797a88a59ad3db0217ca66d
https://doi.org/10.2174/1570162033352066
https://doi.org/10.2174/1570162033352066
Autor:
Michael D. Lumpkin, Bryan Sandler, Matthew Vance, Douglas J. Dieter, Michael R. Ruff, Janice D. Rone, Robin Nixon, Candace B. Pert, Laura Redwine
Publikováno v:
Clinical Immunology. 93:124-131
We previously reported that certain short gp120 V2 region peptides homologous to vasaoactive intestinal peptide (VIP), such as "peptide T," were potent inhibitors of gp120 binding, infectivity, and neurotoxicity. The present study shows that syntheti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533882accd86674d2328bf4571b6a8a3
https://doi.org/10.1006/clim.1999.4771
https://doi.org/10.1006/clim.1999.4771
Autor:
Ewa Karwatowska-Prokopczuk, Hong Ji, Lois T. Hunt, Zofia Zukowska-Grojec, Candace B. Pert, Michael R. Ruff, Joon Kim
Publikováno v:
Regulatory Peptides. :201-205
Hyperplasia of vascular smooth muscle cells (VSMCs) occurs during HIV infection, part of a spectrum of HIV-mediated cardiovascular and microvascular pathologies. These changes are not due to direct viral infection but may involve the receptor-mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9492b6f7cd5fc59c807fb615ff945a
https://doi.org/10.1016/s0167-0115(98)00069-x
https://doi.org/10.1016/s0167-0115(98)00069-x
Publikováno v:
Peptides. 17:831-837
Because VIP is known to be neurotrophic in vitro, the present study tested whether peptide T (PT), an octapeptide with a pentapeptide sequence homologous to VIP, could prevent nucleus basalis (NBM)-induced degenerative changes in the parietal neocort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15da164ea4aaf4c3de696b9ce2b5c1f
https://doi.org/10.1016/0196-9781(96)00106-4
https://doi.org/10.1016/0196-9781(96)00106-4
Autor:
Michael R. Ruff, Ji Zhang, Xiang Q. Shi, Candace B. Pert, Satyanarayana S.V. Padi, Noel Baichoo, Yuan Q. Zhao
Publikováno v:
PainReferences. 153(1)
Chemokine signaling is important in neuropathic pain, with microglial cells expressing CCR2 playing a well-established key role. DAPTA, a HIV gp120-derived CCR5 entry inhibitor, has been shown to inhibit CCR5-mediated monocyte migration and to attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ddb398552b290b4966521be55212d0
https://pubmed.ncbi.nlm.nih.gov/22033364
https://pubmed.ncbi.nlm.nih.gov/22033364
Autor:
Wen Yue Jiang, Eugene M. Farber, Siba P. Raychaudhuri, Michael R. Ruff, Thomas J. Schall, Candace B. Pert
Publikováno v:
Acta Dermato-Venereologica. 79:9-11
Intraepidermal collections of neutrophils and lymphocytes are unique features of the in£ammatory reaction of psoriasis. Migration of leukocytes from dermis to the epidermis suggests a role for chemotactic agent(s). In recent years, increased levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d36c454d0a4bd9e62953c7d88b390dc
https://doi.org/10.1080/000155599750011615
https://doi.org/10.1080/000155599750011615