Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Candace A. Gilbert"'
Autor:
Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews‐Elger, Xiaoqing Han, Manuel Picon‐Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El‐Ashry, Joyce M. Slingerland
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 10, Pp 1502-1522 (2013)
Abstract Increasing evidence suggests that stem‐like cells mediate cancer therapy resistance and metastasis. Breast tumour‐initiating stem cells (T‐ISC) are known to be enriched in CD44+CD24neg/low cells. Here, we identify two T‐ISC subsets w
Externí odkaz:
https://doaj.org/article/2a91a829954b4d69bd06b21506135799
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 3, Pp 304-318 (2017)
Abstract The angiogenic factor, VEGFA, is a therapeutic target in ovarian cancer (OVCA). VEGFA can also stimulate stem‐like cells in certain cancers, but mechanisms thereof are poorly understood. Here, we show that VEGFA mediates stem cell actions
Externí odkaz:
https://doaj.org/article/0f1b4fb2289b48ca8f2cf0f945f01ce9
Autor:
Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Roel G.W. Verhaak, Ji-Yeon Yang, Tan A. Ince, Xiang-Xi Xu, Diana Azzam, Brian Rabinovich, Isildinha M. Reis, Ellis R. Levin, Ali Pedram, Thiago da Silva, Candace A. Gilbert, Wendy Ullmer, Jun Sun, Pedro Hevia-Paez, Fiona Simpkins
PDF file, 46K, List of genes which have one or more ERE in the promoter upstream 10kb region in 111 genes that overlapped in the High ERα and High p416Src groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7e32693b853855f4eb0925ec381ca3
https://doi.org/10.1158/1078-0432.22446114
https://doi.org/10.1158/1078-0432.22446114
Autor:
Dario C. Altieri, Alonzo H. Ross, Candace A. Gilbert, Christopher M. Raskett, Janet Plescia, Markus D. Siegelin
Supplementary Data from Global Targeting of Subcellular Heat Shock Protein-90 Networks for Therapy of Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132c1659c4f7d05303af6a9b6f7a915e
https://doi.org/10.1158/1535-7163.22485291
https://doi.org/10.1158/1535-7163.22485291
Autor:
Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Roel G.W. Verhaak, Ji-Yeon Yang, Tan A. Ince, Xiang-Xi Xu, Diana Azzam, Brian Rabinovich, Isildinha M. Reis, Ellis R. Levin, Ali Pedram, Thiago da Silva, Candace A. Gilbert, Wendy Ullmer, Jun Sun, Pedro Hevia-Paez, Fiona Simpkins
Purpose: More effective, less toxic treatments for recurrent ovarian cancer are needed. Although more than 60% of ovarian cancers express the estrogen receptor (ER), ER-targeted drugs have been disappointing due to drug resistance. In other estrogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c473c1c95e7a06f5c9f6eff942571d
https://doi.org/10.1158/1078-0432.c.6520653
https://doi.org/10.1158/1078-0432.c.6520653
Data from Global Targeting of Subcellular Heat Shock Protein-90 Networks for Therapy of Glioblastoma
Autor:
Dario C. Altieri, Alonzo H. Ross, Candace A. Gilbert, Christopher M. Raskett, Janet Plescia, Markus D. Siegelin
Drug discovery for complex and heterogeneous tumors now aims at dismantling global networks of disease maintenance, but the subcellular requirements of this approach are not understood. Here, we simultaneously targeted the multiple subcellular compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa32953294f656fdfb8b2533c28b96e3
https://doi.org/10.1158/1535-7163.c.6531876.v1
https://doi.org/10.1158/1535-7163.c.6531876.v1
Supplementary Methods, Figure Legends 1-6 Table 1 from γ-Secretase Inhibitors Enhance Temozolomide Treatment of Human Gliomas by Inhibiting Neurosphere Repopulation and Xenograft Recurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace4bef115d38c4b97f9c85cd436c649
https://doi.org/10.1158/0008-5472.22381778
https://doi.org/10.1158/0008-5472.22381778
Malignant gliomas are treated with a combination of surgery, radiation, and temozolomide (TMZ), but these therapies ultimately fail due to tumor recurrence. In glioma cultures, TMZ treatment significantly decreases neurosphere formation; however, a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e26ce84e8ca54fc21d54feb0053623
https://doi.org/10.1158/0008-5472.c.6499976.v1
https://doi.org/10.1158/0008-5472.c.6499976.v1
Supplementary Figure 3 from γ-Secretase Inhibitors Enhance Temozolomide Treatment of Human Gliomas by Inhibiting Neurosphere Repopulation and Xenograft Recurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8a05dd893b81294ce6d4f7304c1188
https://doi.org/10.1158/0008-5472.22381790.v1
https://doi.org/10.1158/0008-5472.22381790.v1
Supplementary Figure 2 from γ-Secretase Inhibitors Enhance Temozolomide Treatment of Human Gliomas by Inhibiting Neurosphere Repopulation and Xenograft Recurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eafc7d6d69ffc3c74facbe5cf648a10
https://doi.org/10.1158/0008-5472.22381793
https://doi.org/10.1158/0008-5472.22381793