Zobrazeno 1 - 10
of 1 409
pro vyhledávání: '"Cancer subtypes"'
Autor:
Lijin Lin, Yulian Hu, Fang Lei, Xuewei Huang, Xingyuan Zhang, Tao Sun, Weifang Liu, Ru Li, Xiao-Jing Zhang, Jingjing Cai, Zhi-Gang She, Guoping Wang, Hongliang Li
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The American Heart Association recently introduced a novel cardiovascular health (CVH) metric, Life's Essential 8 (LE8), for health promotion. However, the relationship between LE8 and cancer mortality risk remains uncertain. Meth
Externí odkaz:
https://doaj.org/article/9e0bfe083699402dbdd5e342377c3a80
Autor:
Esther M. John, Jocelyn Koo, Amanda I. Phipps, Teri A. Longacre, Allison W. Kurian, Sue A. Ingles, Anna H. Wu, Lisa M. Hines
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-29 (2024)
Abstract Background Associations between reproductive factors and risk of breast cancer differ by subtype defined by joint estrogen receptor (ER), progesterone receptor (PR), and HER2 expression status. Racial and ethnic differences in the incidence
Externí odkaz:
https://doaj.org/article/17c638024b9b4f8abff20d138467095e
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Classifying breast cancer subtypes is crucial for clinical diagnosis and treatment. However, the early symptoms of breast cancer may not be apparent. Rapid advances in high-throughput sequencing technology have led to generating l
Externí odkaz:
https://doaj.org/article/a11e095a40ec426d8ff9efa446064402
Autor:
Leandro Y. S. Okimoto, Rayol Mendonca-Neto, Fabíola G. Nakamura, Eduardo F. Nakamura, David Fenyö, Claudio T. Silva
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background In recent years, researchers have made significant strides in understanding the heterogeneity of breast cancer and its various subtypes. However, the wealth of genomic and proteomic data available today necessitates efficient fram
Externí odkaz:
https://doaj.org/article/bba6169bf35f424e8bdadd9761e3f47f
Autor:
Yue Zhang, Deng Pan, Zhenqiang Ning, Fang Huang, Yiting Wei, Mingming Zhang, Yuanjian Zhang, Li-xin Wang, Yanfei Shen
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Tumor cell-released LC3+ extracellular vesicles (LC3+ EVs) participate in immunosuppression during autophagy and contribute to the occurrence and development of breast cancer. In view of the strong association between the LC3+ EVs and breast
Externí odkaz:
https://doaj.org/article/260e3d8a8e2b4861954f156c662b1b48
Autor:
Yulan Wang, Jing Wu, Jian Zhao, Tianyi Xu, Meng Zhang, Jingjing Liu, Yixuan Wang, Quan Wang, Xiaofeng Song
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102127- (2024)
RNA editing plays an extensive role in the initiation and progression of cancer. However, the overall profile and molecular functions of RNA editing in different ovarian cancer subtypes have not been fully characterized and elucidated. Here, we condu
Externí odkaz:
https://doaj.org/article/a1d6a3018ee84c87a7299ff08ebd76b5
Autor:
Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, Maliha Wajahat, Amy R Dwyer, Isabel Mayayo‐Peralta, Gabriela Gomez, Maarten Altelaar, Roderick Beijersbergen, Balázs Győrffy, Leonie Young, Sabine Linn, Jos Jonkers, Wayne Tilley, Theresa Hickey, Damir Vareslija, Alexander Swarbrick, Wilbert Zwart
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-17 (2023)
Abstract Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate that GR relates to the proliferative capacity of nume
Externí odkaz:
https://doaj.org/article/7f89e9b972df425581429cdb0b5d1a09
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Body fatness is a dynamic exposure throughout life. To provide more insight into the association between body mass index (BMI) and postmenopausal breast cancer, we aimed to examine the age at onset, duration, intensity, and trajec
Externí odkaz:
https://doaj.org/article/ff8075eceda64afb97942340fe701464
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 767 (2024)
When dealing with small targets in lung cancer detection, the YOLO V8 algorithm may encounter false positives and misses. To address this issue, this study proposes an enhanced YOLO V8 detection model. The model integrates a large separable kernel at
Externí odkaz:
https://doaj.org/article/b40d4e6c7dd645a4838bae6f448e7fca
Autor:
Dixan A. Benitez, Guadalupe Cumplido-Laso, Marcos Olivera-Gómez, Nuria Del Valle-Del Pino, Alba Díaz-Pizarro, Sonia Mulero-Navarro, Angel Román-García, Jose Maria Carvajal-Gonzalez
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1453 (2024)
The TP53 gene is renowned as a tumor suppressor, playing a pivotal role in overseeing the cell cycle, apoptosis, and maintaining genomic stability. Dysregulation of p53 often contributes to the initiation and progression of various cancers, including
Externí odkaz:
https://doaj.org/article/ca37f5033ea947179f817b30af93d3b7