Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Cancer stem-like cell"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Hypoxia-activated prodrug (HAP) is a promising candidate for highly tumor-specific chemotherapy. However, the oxygenation heterogeneity and dense extracellular matrix (ECM) of tumor, as well as the potential resistance to chemothe
Externí odkaz:
https://doaj.org/article/276df78219af414d902951c7d3dafbfb
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1262-1273 (2023)
Drug resistance presents one of the major causes for the failure of cancer chemotherapy. Cancer stem-like cells (CSCs), a population of self-renewal cells with high tumorigenicity and innate chemoresistance, can survive conventional chemotherapy and
Externí odkaz:
https://doaj.org/article/c0f1a52bc7cb4219abdd1dfe1636f09a
Autor:
Xiaojing Du, Zhuoran Qi, Jinzhi Xu, Mengzhou Guo, Xingxing Zhang, Zhijie Yu, Xin Cao, Jinglin Xia
Publikováno v:
Molecular Oncology, Vol 16, Iss 20, Pp 3703-3719 (2022)
Cancer stem‐like cells (CSLC) are considered a major contributor to the development and progression of hepatocellular carcinoma (HCC). Previous studies indicated that CSLC are characterized by resistance to ferroptosis, a type of lipid peroxidation
Externí odkaz:
https://doaj.org/article/2b26c75b31ef425bbe1c7bb44cd6af96
Autor:
Juhong Wang, Fei Shao, Yannan Yang, Wei Wang, Xueying Yang, Renda Li, Hong Cheng, Sijin Sun, Xiaoli Feng, Yibo Gao, Jie He, Zhimin Lu
Publikováno v:
Cancer Communications, Vol 42, Iss 10, Pp 1008-1027 (2022)
Abstract Background Maintenance of cancer stem‐like cell (CSC) stemness supported by aberrantly regulated cancer cell metabolism is critical for CSC self‐renewal and tumor progression. As a key glycolytic enzyme, hexokinase 2 (HK2) plays an instr
Externí odkaz:
https://doaj.org/article/f0447df5dead44edb66f0ed6121fb6c4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jin Gu Cho, Sung-wook Kim, Aram Lee, Ha-neul Jeong, Eunsik Yun, Jihea Choi, Su Jin Jeong, Woochul Chang, Sumin Oh, Kyung Hyun Yoo, Jung Bok Lee, Sukjoon Yoon, Myeong-Sok Lee, Jong Hoon Park, Min Hyung Jung, So-Woon Kim, Ki Hyung Kim, Dong Soo Suh, Kyung Un Choi, Jungmin Choi, Jongmin Kim, Byung Su Kwon
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 803-822 (2022)
Cancer stem-like cells (CSCs) have been suggested to be responsible for chemoresistance and tumor recurrence owing to their self-renewal capacity and differentiation potential. Although WEE1 is a strong candidate target for anticancer therapies, its
Externí odkaz:
https://doaj.org/article/2292e1739f1e48f0a24e453d19fda611
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Wei Tian, Jiatong Li, Zhuo Wang, Tong Zhang, Ying Han, Yanyan Liu, Wenfeng Chu, Yu Liu, Baofeng Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1592-1606 (2021)
HYD-PEP06, an endostatin-modified polypeptide, has been shown to produce effective anti-colorectal carcinoma effects through inhibiting epithelial–mesenchymal transition (EMT). However, whether HYD-PEP06 has similar suppressive effect on hepatocell
Externí odkaz:
https://doaj.org/article/395955f90292441fb6f4f80ff5cd6811
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Shuhei Kamada, Kazuhiro Ikeda, Takashi Suzuki, Wataru Sato, Sachi Kitayama, Satoru Kawakami, Tomohiko Ichikawa, Kuniko Horie, Satoshi Inoue
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundAcquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently char
Externí odkaz:
https://doaj.org/article/e53d373d31574ad4a198a924982b9911