Zobrazeno 1 - 10
of 588
pro vyhledávání: '"Cancer stem cell (CSC)"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cancer stem cells (CSCs) have the potential to self-renew and induce cancer, which may contribute to a poor prognosis by enabling metastasis, recurrence, and therapy resistance. Hence, this study was performed to identify the association bet
Externí odkaz:
https://doaj.org/article/8824695dcd1b4090affa6514bc9533fb
Autor:
Mi-Hyeon You
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7086-7096 (2024)
Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin (Ca2+/CaM)-dependent serine/threonine (Ser/Thr) protein kinase and is characteristically downregulated in metastatic cancer. Several studies showed that DAPK1 is involved in both the e
Externí odkaz:
https://doaj.org/article/a0ac9b8a5e5a4aac874920bdebfb631c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/082b54e4eee94199994b345b15eafdc4
Autor:
Jee-Eun Choi, Inwha Baek
Publikováno v:
Frontiers in Epigenetics and Epigenomics, Vol 2 (2024)
Tumors consist of cancer cells with different genetic, epigenetic, and phenotypic properties. Cancer stem cells are an important subpopulation of heterogeneous cancer cells and are capable of initiating and propagating tumors. The term cancer stem ce
Externí odkaz:
https://doaj.org/article/e4ceee96c5724cd9aec9567d97d51718
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract The primary challenge in treating esophageal squamous cell carcinoma (ESCC) is resistance to chemotherapy. Cancer stem cell (CSC) is the root cause of tumor drug resistance. Therefore, targeting CSCs has been considered promising therapeutic
Externí odkaz:
https://doaj.org/article/21d2d623ddd6464da02f34d28f07a21f
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/1e6142df77434627a0f548a8abe64c49
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide and has a poor prognosis. Although immune checkpoint inhibitors have entered a new era of HCC treatment, their response rates are modest, which can be attributed to th
Externí odkaz:
https://doaj.org/article/ce6aea33b01440bea89adb0b5859ae45
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Cancer stem cells (CSCs) have emerged as key contributors to tumor initiation, growth, and metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby compromising the effectiveness of cancer treatments. The rec
Externí odkaz:
https://doaj.org/article/3e6a2437760f45f5a7a59383af1fafe2
Autor:
Surendra Kumar Acharya, Saptarsi Shai, Yee Fan Choon, Indrayadi Gunardi, Firstine Kelsi Hartanto, Kathreena Kadir, Ajoy Roychoudhury, Rahmi Amtha, Vui King Vincent-Chong
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2111 (2024)
Cancer stem cells (CSCs) represent a subpopulation of cancer cells that are believed to initiate and drive cancer progression. In animal models, xenotransplanted CSCs have demonstrated the ability to produce tumors. Since their initial isolation in b
Externí odkaz:
https://doaj.org/article/22cb5a013f42409388984fe1cda29435
Autor:
Keywan Mortezaee, Jamal Majidpoor
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23171- (2023)
Tumor-mediated bypass of immune checkpoint inhibitor (ICI) therapy with anti-programmed death-1 (PD-1), anti-programmed death-ligand 1 (PD-L1, also called B7–H1 or CD274) or anti-cytotoxic T lymphocyte associated antigen-4 (CTLA-4) is a challenge o
Externí odkaz:
https://doaj.org/article/0def576a2d0d4a0b9265ce5261f24f79