Zobrazeno 1 - 10
of 41 168
pro vyhledávání: '"Cancer stem cell"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Placenta-specific protein 1 (PLAC-1) is a gene primarily expressed in the placenta and the testis. Interestingly, it is also found to be expressed in many solid tumors, and it is involved in malignant cell features. However, no evidence has
Externí odkaz:
https://doaj.org/article/9f11ce5b0be2440db20a243b4b8aa04a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract The prognosis for patients with colorectal cancer (CRC) remains worse than expected due to metastasis, recurrence, and resistance to chemotherapy. Colorectal cancer stem cells (CRCSCs) play a vital role in tumor metastasis, recurrence, and c
Externí odkaz:
https://doaj.org/article/3d146d6c1a54454abf0546f0ed6f51ed
Autor:
Rupali Sarkar, Souradeep Biswas, Rituparna Ghosh, Priya Samanta, Shampa Pakhira, Mrinmoyee Mondal, Yashaswi Dutta Gupta, Suman Bhandary, Prosenjit Saha, Arijit Bhowmik, Subhadip Hajra
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Background Therapeutic management of locally advanced and metastatic triple negative breast cancer (TNBC) is often limited due to resistance to conventional chemotherapy. Metastasis is responsible for more than 90% of breast cancer-associate
Externí odkaz:
https://doaj.org/article/af7752ac3fcc4b118c94b840544c423f
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Cancer stem cells (CSCs) represent both a key driving force and therapeutic target of tumoral carcinogenesis, tumor evolution, progression, and recurrence. CSC-guided tumor diagnosis, treatment, and surveillance are strategically significant
Externí odkaz:
https://doaj.org/article/8a84b6d62bef465a94ca4e23092a7ebc
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-47 (2024)
Abstract Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively associated with highly curved and prominent membrane structures. It is widely recognized as an antigenic marker of stem cells and cancer stem cells and is frequent
Externí odkaz:
https://doaj.org/article/71b271e35210426da4266ab0ab5b0bc8
Autor:
Lin Ding, Hui Jiang, Qiangwei Li, Qiushuang Li, Tian-Tian Zhang, Limeng Shang, Bin Xie, Yaling Zhu, Keshuo Ding, Xuanming Shi, Tao Zhu, Yong Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Ropivacaine, a local anesthetic, exhibits anti-tumor effects in various cancer types. However, its specific functions and the molecular mechanisms involved in breast cancer cell stemness remain elusive. Methods The effects of ropi
Externí odkaz:
https://doaj.org/article/400f21f852114aa99cf101782140c32e
Autor:
Motoharu Sarubo, Yasuhiro Mouri, Akira Moromizato, Azusa Yamada, Shengjan Jin, Wenhua Shao, Hiroko Hagita, Keiko Miyoshi, Yasusei Kudo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Head and neck squamous cell carcinoma (HNSCC) is a significant healthcare burden globally. Previous research using single-cell transcriptome analysis identified TGFBI as a crucial marker for the partial-epithelial-mesenchymal transition (par
Externí odkaz:
https://doaj.org/article/c88d1ee100cd40d4b66fe70630dc971e
Autor:
Jung Hyun Jo, Soo Been Park, Joowon Chung, Taeyun Oh, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Dawoon E. Jung, Si Young Song
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Biliary tract cancer (BTC) is a relatively rare but aggressive gastrointestinal cancer with a high mortality rate. Cancer stem cell (CSC) populations play crucial roles in tumor biology and are responsible for the low response to
Externí odkaz:
https://doaj.org/article/540fbdef04374f1dbacc19d8c197fc16
Autor:
Alejandra I. Ferrer-Diaz, Garima Sinha, Andrew Petryna, Ruth Gonzalez-Bermejo, Yannick Kenfack, Oluwadamilola Adetayo, Shyam A. Patel, Anupama Hooda-Nehra, Pranela Rameshwar
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Breast cancer cells (BCCs) can remain undetected for decades in dormancy. These quiescent cells are similar to cancer stem cells (CSCs); hence their ability to initiate tertiary metastasis. Dormancy can be regulated by components
Externí odkaz:
https://doaj.org/article/1f56bd6110494069ba55e62935daf8ed
Autor:
Ee Wern Tan, Amar Daud Iskandar Abdullah, Long Chiau Ming, Chit Laa Poh, Bey Hing Goh, Tze Pheng Lau, Kuan Onn Tan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116744- (2024)
Cancer is one of the major leading causes of mortality globally and chemo-drug-resistant cancers pose significant challenges to cancer treatment by reducing patient survival rates and increasing treatment costs. Although the mechanisms of chemoresist
Externí odkaz:
https://doaj.org/article/11e0dda9558e489c9e574098bdd6f361