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From netrin‐1‐targeted SPECT / CT to internal radiotherapy for management of advanced solid tumors

Autor: David Kryza, Jennifer Wischhusen, Mathieu Richaud, Maëva Hervieu, Jacqueline Sidi Boumedine, Jean‐Guy Delcros, Sophie Besse, Thomas Baudier, Pierre‐Alexandre Laval, Silvia Breusa, Erwan Boutault, Hugo Clermidy, Nicolas Rama, Benjamin Ducarouge, Mojgan Devouassoux‐Shisheboran, Jean‐Michel Chezal, Anne‐Laure Giraudet, Thomas Walter, Patrick Mehlen, David Sarrut, Benjamin Gibert

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, 2023, 15, ⟨10.15252/emmm.202216732⟩

International audience; Targeted radionuclide therapy is a revolutionary tool for the treatment of highly spread metastatic cancers. Most current approaches rely on the use of vectors to deliver radionuclides to tumor cells, targeting membrane-bound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9bcbf1f2752c2a6e92c99edabd903c
https://cnrs.hal.science/hal-04107206

The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models

Autor: Hussain, Nosheen, Connah, David, Ugail, Hassan, Cooper, Patricia A., Falconer, Robert A., Patterson, Laurence H., Shnyder, Steven

Yes
Non-invasive methods to monitor tumour growth are an important goal in cancer drug development. Thermographic imaging systems offer potential in this area, since a change in temperature is known to be induced due to changes within the tumour

Externí odkaz: http://hdl.handle.net/10454/8781

Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

Autor: Milene Volpato, John Hutchinson, Catriona Marshall, P. Louise Coletta, Jade A. Spencer, Nicola Ingram, SL Perry, Anna Nicolaou, Paul M. Loadman, Mark A. Hull, Amanda D. Race

Publikováno v: Nicolaou, A & et al. 2020, ' Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid ', Cancer Chemotherapy and Pharmacology . https://doi.org/10.1007/s00280-020-04157-2
Cancer Chemother Pharmacol
Cancer Chemotherapy and Pharmacology

PurposeThe naturally-occurring omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and inexpensive, making it an attractive anti-cancer intervention. However, EPA has only modest anti-colorectal cancer (CRC) activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de86493b213c066d2f4df5e4d849c186
https://doi.org/10.1007/s00280-020-04157-2