Zobrazeno 1 - 10
of 6 915
pro vyhledávání: '"Cancer metabolism"'
Autor:
LIU Ke, DAI Menghua
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 11, Pp 1613-1617 (2024)
Pancreatic cancer relies on glutamine (Gln) in its carcinogenesis. Gln metabolism is reprogrammed by multiple oncogenes and their downstream effectors in pancreatic cancer cells. The Gln dependence and its underlying molecular mechanisms can potentia
Externí odkaz:
https://doaj.org/article/54b1233f8c0c4d51bea8b2343415342a
Autor:
Amirhossein Shahpar, Vahideh Hamidi Sofiani, Nazanin Zeinali Nezhad, Marzieh Charostad, Reza Ghaderi, Niloofar Farsiu, Amin Karimzadeh Kiskani, Sara Pezeshki, Mohsen Nakhaie
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Introduction In this narrative review, we unravel the complex interplay between oncogenic viruses, cellular metabolism, and glucose transporter (GLUT) dysregulation in viral-induced malignancies. Methods By explaining the diverse mechanisms
Externí odkaz:
https://doaj.org/article/7e6bb3118812460ba9c498d1e9f6c200
Autor:
Francesco Gatto, Sinisa Bratulic, Francesca Maccari, Fabio Galeotti, Nicola Volpi, Jens Nielsen, Yair Lotan, Henrik Kjölhede
Publikováno v:
European Urology Open Science, Vol 68, Iss , Pp 40-47 (2024)
Background and objective: Screening for bladder cancer (BCa) could reduce mortality via early detection of early-stage high-grade (Ta/T1 N0 M0 grade 2–3) disease. Noninvasive biomarkers could aid in screening, but current markers lack the specifici
Externí odkaz:
https://doaj.org/article/ea6532441b704085861bdd4e804a3f8e
Autor:
Jing Wang, He-Kang Ding, Han-Jiang Xu, De-Kai Hu, William Hankey, Li Chen, Jun Xiao, Chao-Zhao Liang, Bing Zhao, Ling-Fan Xu
Publikováno v:
Asian Journal of Andrology, Vol 26, Iss 5, Pp 451-463 (2024)
Tumor metabolic reprogramming is a hallmark of cancer development, and targeting metabolic vulnerabilities has been proven to be an effective approach for castration-resistant prostate cancer (CRPC) treatment. Nevertheless, treatment failure inevitab
Externí odkaz:
https://doaj.org/article/460fbeac57cf4d20964db8f66e364717
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-40 (2024)
Abstract Cancer cells undergo significant metabolic reprogramming to support their rapid growth and survival. This study examines important metabolic pathways like glycolysis, oxidative phosphorylation, glutaminolysis, and lipid metabolism, focusing
Externí odkaz:
https://doaj.org/article/0f46445dc1cf4dd8a3e82f8ed5282fee
Autor:
Xi Hu, Daishun Ling
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4619-4621 (2024)
Externí odkaz:
https://doaj.org/article/250a63c16b1a4c2eae9c6639ed344642
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1739-1758 (2024)
Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that,
Externí odkaz:
https://doaj.org/article/102a7d6cbe1d40af8d442682b439fc17
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1378-1396 (2024)
Ferroptosis is a newly identified iron‐dependent type of regulated cell death that can also be regarded as death caused by the specific collapse of the lipid antioxidant defence machinery. Ferroptosis has gained increasing attention as a potential
Externí odkaz:
https://doaj.org/article/38f7163513404f828b66e741db4d1b13
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract KDM6A (lysine demethylase 6A) has been reported to undergo inactivating mutations in colorectal cancer, but its function in the progression of colorectal cancer has not been evaluated using animal models of colorectal cancer. In this study,
Externí odkaz:
https://doaj.org/article/55c3588e907546f2a7d869c55e20d6d3
Autor:
Zhe Zhou, Di Dong, Yuyao Yuan, Juan Luo, Xiao-Ding Liu, Long-Yun Chen, Guangxi Wang, Yuxin Yin
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105389- (2024)
Summary: Background: Metabolic reprogramming plays a pivotal role in cancer progression, contributing to substantial intratumour heterogeneity and influencing tumour behaviour. However, a systematic characterization of metabolic heterogeneity across
Externí odkaz:
https://doaj.org/article/82db8245e59a4b12b9025be6a05f2489