Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Cancer immunoprevention"'
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Cancer immunoprevention is based on the fact that a functioning immune system controls tumor onset and development in humans and animals, thus leading to the idea that the enhancement of immune responses in healthy individuals could effectiv
Externí odkaz:
https://doaj.org/article/b3b8be3c9db44811b539b373832a0824
Publikováno v:
Vaccines, Vol 3, Iss 2, Pp 467-489 (2015)
Years of unsuccessful attempts at fighting established tumors with vaccines have taught us all that they are only able to truly impact patient survival when used in a preventive setting, as would normally be the case for traditional vaccines against
Externí odkaz:
https://doaj.org/article/cf662f7b06864868a80f504c65ed4417
Akademický článek
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Publikováno v:
Cancer Prevention Research. 13:897-900
Cancer immunoprevention is achieved through promoting antitumor immune surveillance to block tumor formation and progression. Following the success of prophylactic vaccines against human papillomavirus (HPV) in preventing HPV-associated cancer, immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5870c288d39717b501ac55effea88bc1
https://doi.org/10.1158/1940-6207.capr-20-0432
https://doi.org/10.1158/1940-6207.capr-20-0432
Publikováno v:
Cancer Prevention Research. 13:351-356
Immune checkpoint blockade therapy provides substantial benefits for subsets of patients with advanced cancer, but its utility for cancer prevention is unknown. Lynch syndrome (MIM 120435) is characterized by defective DNA mismatch repair and predisp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce759fec0146918d4b5995c1f41d666
https://doi.org/10.1158/1940-6207.capr-19-0528
https://doi.org/10.1158/1940-6207.capr-19-0528
Autor:
William S. Bowen, Pradeep Shrestha, Hong Zhao, Lalit Batra, Jorge G. Gomez-Gutierrez, Hampartsoum B. Barsoumian, Esma S. Yolcu, Haval Shirwan, Nejat K. Egilmez
Publikováno v:
Cancer Research. 79:783-794
Costimulation through 4-1BB (CD137) receptor generates robust CD8+ T-effector and memory responses. The only known ligand, 4-1BBL, is a trimeric transmembrane protein that has no costimulatory activity as a soluble molecule. Thus, agonistic antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968b9f7eaf7b399c0e9baa10513b20f7
https://doi.org/10.1158/0008-5472.can-18-2401
https://doi.org/10.1158/0008-5472.can-18-2401
Autor:
Lin Tang, Bingbing Wang, V. Escamilla-Rivera, Jin Wang, Cassandra L. Gonzalez, Adel K. El-Naggar, Yuan Hu, Jeffrey N. Myers, Carlos Caulin
Publikováno v:
Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1471, p 1471 (2021)
Volume 13
Issue 6
Cancers, Vol 13, Iss 1471, p 1471 (2021)
Simple Summary Immune checkpoint blockade with anti-PD-1 antibodies blocks the development of oral squamous cell carcinomas (OSCCs) in preclinical models. Understanding whether the genetic alterations that accumulate during oral cancer development af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd54c5935c44d5dc2698bc8aa579e50
Autor:
Nima Rezaei, Mahsa Keshavarz-Fathi
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 69
Cancer is one of the most serious diseases affecting health and the second leading cause of death worldwide. Despite the development of various therapeutic modalities to deal with cancer, limited improvement in overall survival of patients has been y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58dc66f0c7425eb67b658d45502b9f75
https://doi.org/10.1007/s00005-021-00604-x
https://doi.org/10.1007/s00005-021-00604-x
Publikováno v:
Molecular carcinogenesisREFERENCES. 59(7)
The ultimate success of any form of cancer therapy or cancer prevention depends on its ability to engage the power of the immune system to completely eliminate a growing tumor, lower the life-time tumor risk and establish long-term memory to prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64732e27005e5070a6402ce26b598b7b
https://pubmed.ncbi.nlm.nih.gov/32333615
https://pubmed.ncbi.nlm.nih.gov/32333615
Autor:
Nina Nelius, Alejandro Hernandez-Sanchez, Yurong Song, Lei Wei, Nan Deng, Winfried Edelmann, Katharina Urban, Ozkan Gelincik, Johannes Gebert, Ali Elsaadi, Elena Tosti, Yan P. Yuan, Vera Fuchs, Matthias Kloor, Mine Oezcan-Wahlbrink, Aysel Ahadova, Eva Maria Katzenmaier, Peer Bork, Jason D. Marshall, Robert H. Shoemaker, Song Liu, Steven M. Lipkin, Mark D. Long, Magnus von Knebel Doeberitz, Shizuko Sei, Asad Umar, Eduardo Vilar, Eduardo Cortes
Publikováno v:
Gastroenterology
Background & Aims DNA mismatch repair deficiency drives microsatellite instability (MSI). Cells with MSI accumulate numerous frameshift mutations. Frameshift mutations affecting cancer-related genes may promote tumorigenesis and, therefore, are share
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ed83bca1b73b6e9c142d36dcb8c055
https://doi.org/10.1053/j.gastro.2021.06.073
https://doi.org/10.1053/j.gastro.2021.06.073