Zobrazeno 1 - 10
of 770
pro vyhledávání: '"Cancer hallmarks"'
Autor:
Xzaviar K. Solone, Siddhi Chitre, Laura Falceto Font, Kimberly N. Espinoza Pereira, Kathryn Stofer, Dietmar W. Siemann
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Previous graduate students and postdoctoral associates from the University of Florida Health Cancer Center, in partnership with the University of Florida Student Science Training Program, implemented a cooperative learning curricu
Externí odkaz:
https://doaj.org/article/2c380804bfb34c19a1436489186952a3
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high rates of morbidity and death. Interestingly, it has also been linked to cancer, which begs the issue of whether it plays a role in carcinogenesis. Recent st
Externí odkaz:
https://doaj.org/article/2930294f41ac417a84c7f0c21f2e3081
Autor:
Fangfang Liu, Jingyu Chen, Kai Li, Haochen Li, Yiyi Zhu, Yubo Zhai, Bingbing Lu, Yanle Fan, Ziyue Liu, Xiaojie Chen, Xuechao Jia, Zigang Dong, Kangdong Liu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-50 (2024)
Abstract Ubiquitination, a pivotal posttranslational modification of proteins, plays a fundamental role in regulating protein stability. The dysregulation of ubiquitinating and deubiquitinating enzymes is a common feature in various cancers, undersco
Externí odkaz:
https://doaj.org/article/60bb33dd28884da89151376617db8aa5
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Carcinogenesis is driven by interactions between genetic mutations and the local tumor microenvironment. Recent research has identified hundreds of cancer driver genes; however, these studies often include a mixture of different m
Externí odkaz:
https://doaj.org/article/d17d69192e5c43688aed0b790d34f27f
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The complexity of cancer requires a comprehensive approach to understand its diverse manifestations and underlying mechanisms. Initially outlined by Hanahan and Weinberg in 2000 and updated in 2010, the hallmarks of cancer provide a conceptual basis
Externí odkaz:
https://doaj.org/article/0f5b618b396741ca8f63a1536ae70157
Autor:
Mariola Gimła, Anna Herman-Antosiewicz
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2199 (2024)
Cancer, a complex group of diseases marked by uncontrolled cell growth and invasive behavior, is characterized by distinct hallmarks acquired during tumor development. These hallmarks, first proposed by Douglas Hanahan and Robert Weinberg in 2000, pr
Externí odkaz:
https://doaj.org/article/153f337739624216bb5a2d25c3e71dc7
Autor:
Wamidh H. Talib, Ilia Abed, Daniah Raad, Raghad K. Alomari, Ayah Jamal, Rand Jabbar, Eman Omar Amin Alhasan, Heba K. Alshaeri, Moudi M. Alasmari, Douglas Law
Publikováno v:
Foods, Vol 13, Iss 17, p 2687 (2024)
Cancer continues to be a prominent issue in healthcare systems, resulting in approximately 9.9 million fatalities in 2020. It is the second most common cause of death after cardiovascular diseases. Although there are difficulties in treating cancer a
Externí odkaz:
https://doaj.org/article/40778464f00f4d8289e26c475f4e438c
Autor:
Mukulika Bose
Publikováno v:
International Journal of Translational Medicine, Vol 3, Iss 3, Pp 334-359 (2023)
Preferentially expressed antigen in melanoma (PRAME) is a cancer testis antigen (CTA) that is selectively expressed in certain somatic tissues, predominantly in the testis, and is overexpressed in various cancers. PRAME family proteins are leucine-ri
Externí odkaz:
https://doaj.org/article/d87ffacf4fe846448a5a16cab6ac1751
Publikováno v:
Annals of the National Academy of Medical Sciences (India), Vol 59, Iss 03, Pp 152-157 (2023)
Background Cystatin A (CSTA), an endogenous inhibitor of lysosomal cysteine protease, is expressed primarily in epithelial tissues. The expression of CSTA was found to be dysregulated in various cancers and associated with cancer pathogenesis, but it
Externí odkaz:
https://doaj.org/article/9d9819d897934d0badb59dcfa93e7b76
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background Disrupted protein homeostasis (proteostasis) has been demonstrated to facilitate the progression of various diseases. The cytosolic T‐complex protein‐1 ring complex (TRiC/CCT) was discovered to be a critical player in orchestr
Externí odkaz:
https://doaj.org/article/6dffd993fa9841afb9d3e6897beabf95