Zobrazeno 1 - 10
of 9 331
pro vyhledávání: '"Cancer genome"'
Autor:
Takeshi Nagashima, Ken Yamaguchi, Kenichi Urakami, Yuji Shimoda, Sumiko Ohnami, Keiichi Ohshima, Tomoe Tanabe, Akane Naruoka, Fukumi Kamada, Masakuni Serizawa, Keiichi Hatakeyama, Shumpei Ohnami, Koji Maruyama, Tohru Mochizuki, Maki Mizuguchi, Akio Shiomi, Yasuhisa Ohde, Etsuro Bando, Teiichi Sugiura, Takashi Mukaigawa, Seiichiro Nishimura, Yasuyuki Hirashima, Koichi Mitsuya, Shusuke Yoshikawa, Yoshio Kiyohara, Yasuhiro Tsubosa, Hirohisa Katagiri, Masashi Niwakawa, Kaoru Takahashi, Hiroya Kashiwagi, Yoshichika Yasunaga, Yuji Ishida, Takashi Sugino, Hirotsugu Kenmotsu, Masanori Terashima, Mitsuru Takahashi, Katsuhiko Uesaka, Yasuto Akiyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In cancer genome analysis, identifying pathogenic alterations and assessing their effects on oncogenic processes is important. Although whole exome sequencing (WES) can effectively detect such changes, driver alterations could not be identif
Externí odkaz:
https://doaj.org/article/78e02debd67d4858aa07bf66640f5372
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 11, Pp 1156-1172 (2024)
Abstract The 3D genome prediction in cancer is crucial for uncovering the impact of structural variations (SVs) on tumorigenesis, especially when they are present in noncoding regions. We present InfoHiC, a systemic framework for predicting the 3D ca
Externí odkaz:
https://doaj.org/article/56ee9efbf26e48459167206cbba57bc8
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Acute myeloid leukemia (AML) is a highly heterogeneous hematological neoplasm, highlighting the need for new molecular markers to improve prognosis prediction and therapeutic strategies. While Rho guanine nucleotide exchange factor 5 (ARHGEF
Externí odkaz:
https://doaj.org/article/4e39d457b53342dab55dc10811b53945
Autor:
Joni Yadav, Apoorva Chaudhary, Tanya Tripathi, Divya Janjua, Udit Joshi, Nikita Aggarwal, Arun Chhokar, Chetkar Chandra Keshavam, Anna Senrung, Alok Chandra Bharti
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract Background HPV status in a subset of HNSCC is linked with distinct treatment outcomes. Present investigation aims to elucidate the distinct clinicopathological features of HPV-positive and HPV-negative HNSCC and investigate their association
Externí odkaz:
https://doaj.org/article/04664fb90ad845f480cdab138b5f692a
Publikováno v:
Zhongguo gonggong weisheng, Vol 40, Iss 8, Pp 997-1005 (2024)
ObjectiveTo construct a prognostic risk scoring model for gastric cancer (GC) anoikis-related genes (ARGs) based on least absolute shrinkage and selection operator (LASSO) regression, and analyze the relationship between anoikis and prognosis of gast
Externí odkaz:
https://doaj.org/article/620741cc80094ab5ad0f6926dc75a352
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Purpose This study aimed to elucidate the predictive role of an oxidative stress-related genes (OSRGs) model in colon cancer. Materials and methods First, OSRGs that were differentially expressed between tumor and normal tissues were identif
Externí odkaz:
https://doaj.org/article/58c11c0f7ca7476da1aea7e3c3786302
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 1301-14 (2024)
This study aims to address the substantive issue of lacking reliable prognostic biomarkers in hepatocellular carcinoma (HCC) by investigating the relationship between TP53-inducible glycolysis and apoptosis regulator (TIGAR) and HCC prognosis using T
Externí odkaz:
https://doaj.org/article/ea4291dd8c2a43b1a0ca4402c04a7a74
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 2, Pp 40-49 (2024)
Gastric cancer if the 5th most common oncological disease in the world and one of the leading causes of death associated with this pathology. In clinical practice, the Lauren classification is widely used for gastric cancer characterization, but it d
Externí odkaz:
https://doaj.org/article/4a53831484fa4958b9a1f32dd75d607b
Autor:
Daniall Masood, Luyao Ren, Cu Nguyen, Francesco G. Brundu, Lily Zheng, Yongmei Zhao, Erich Jaeger, Yong Li, Seong Won Cha, Aaron Halpern, Sean Truong, Michael Virata, Chunhua Yan, Qingrong Chen, Andy Pang, Reyes Alberto, Chunlin Xiao, Zhaowei Yang, Wanqiu Chen, Charles Wang, Frank Cross, Severine Catreux, Leming Shi, Julia A. Beaver, Wenming Xiao, Daoud M. Meerzaman
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Copy number variation (CNV) is a key genetic characteristic for cancer diagnostics and can be used as a biomarker for the selection of therapeutic treatments. Using data sets established in our previous study, we benchmark the per
Externí odkaz:
https://doaj.org/article/cc6fa948e2fb4ac38130b50d9697979b
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Disulfidptosis represents a novel cell death mechanism triggered by disulfide stress, with potential implications for advancements in cancer treatments. Although emerging evidence highlights the critical regulatory roles of long non-coding R
Externí odkaz:
https://doaj.org/article/f546040ecbe74d718b1beb9630e12762