Zobrazeno 1 - 10
of 588
pro vyhledávání: '"Cancer cell metabolism"'
Publikováno v:
Cells, Vol 13, Iss 18, p 1533 (2024)
Cancer cells can release EGF-like peptides, acquiring the capacity of autocrine stimulation via EGFR-mediated signaling. One of these peptides (HBEGF) was found to be released from a membrane-bound precursor protein and is critically implicated in th
Externí odkaz:
https://doaj.org/article/83e6b96da94b4200932f7706dea65181
Autor:
Giorgia Ciufolini, Serena Zampieri, Simona Cesaroni, Valentina Pasquale, Marcella Bonanomi, Daniela Gaglio, Elena Sacco, Marco Vanoni, Mirella Pastore, Fabio Marra, Daniel Oscar Cicero, Chiara Raggi, Greta Petrella
Publikováno v:
Cells, Vol 13, Iss 18, p 1536 (2024)
Developing accurate in vitro models that replicate the in vivo tumor environment is essential for advancing cancer research and therapeutic development. Traditional 2D cell cultures often fail to capture the complex structural and functional heteroge
Externí odkaz:
https://doaj.org/article/7573ea8112da48f383a43e0382cbe6d1
Publikováno v:
Cells, Vol 12, Iss 20, p 2486 (2023)
Modulation of autophagy as an anticancer strategy has been widely studied and evaluated in several cell models. However, little attention has been paid to the metabolic changes that occur in a cancer cell when autophagy is inhibited or induced. In th
Externí odkaz:
https://doaj.org/article/04ddbca83f114a84a41262836e115d65
Publikováno v:
Radiology and Oncology, Vol 55, Iss 4, Pp 379-392 (2021)
MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in almost all biological pathways. They regulate post-transcriptional gene expression by binding to the 3’untranslated region (3’UTR) of messenger RNAs (mRNAs). MitomiRs are m
Externí odkaz:
https://doaj.org/article/1469eb1f0451409ca66c7e70ead926e4
Autor:
Yogesh Rai, Saurabh Singh, Sanjay Pandey, Dhananjay Sah, Raj Kumar Sah, B. G. Roy, Bilikere S. Dwarakanath, Anant Narayan Bhatt
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionCancer bioenergetics is an essential hallmark of neoplastic transformation. Warburg postulated that mitochondrial OXPHOS is impaired in cancer cells, leading to aerobic glycolysis as the primary metabolic pathway. However, mitochondrial f
Externí odkaz:
https://doaj.org/article/8540cda1c5f740fba0c62a0542a8e60f
Publikováno v:
Royal Society Open Science, Vol 9, Iss 10 (2022)
Computer-aided methods can be used to screen potential candidate targets and to reduce the time and cost of drug development. In most of these methods, synthetic lethality is used as a therapeutic criterion to identify drug targets. However, these me
Externí odkaz:
https://doaj.org/article/b2730094a8a04f64a67f3f30b7428b74
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Carla Luís, Bárbara Guerra-Carvalho, Patrícia C. Braga, Carla Guedes, Emília Patrício, Marco G. Alves, Ruben Fernandes, Raquel Soares
Publikováno v:
Cells, Vol 12, Iss 17, p 2123 (2023)
Molecular subtype (MS) is one of the most used classifications of breast cancer (BC). Four MSs are widely accepted according to receptor expression of estrogen, progesterone, and HER2. The impact of adipose tissue on BC MS metabolic impairment is sti
Externí odkaz:
https://doaj.org/article/24352d2e1f1a42839435e0f40a7bef0f
Publikováno v:
FEBS Open Bio, Vol 11, Iss 8, Pp 2078-2094 (2021)
Cancer cell dysregulations result in the abnormal regulation of cellular metabolic pathways. By simulating this metabolic reprogramming using constraint‐based modeling approaches, oncogenes can be predicted, and this knowledge can be used in progno
Externí odkaz:
https://doaj.org/article/96bbf0b07f694e46b1d277993527ec0f