Zobrazeno 1 - 10
of 1 947
pro vyhledávání: '"Cancer Microenvironment"'
Autor:
Kevin Lee, Wimeth Dissanayake, Melissa MacLiesh, Cih-Li Hong, Zi Yin, Yuko Kawano, Christina M. Kaszuba, Hiroki Kawano, Emily R. Quarato, Brian Marples, Michael Becker, Jeevisha Bajaj, Laura M. Calvi, Shu-Chi A. Yeh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Recent advances in imaging suggested that spatial organization of hematopoietic cells in their bone marrow microenvironment (niche) regulates cell expansion, governing progression, and leukemic transformation of hematological clonal disorder
Externí odkaz:
https://doaj.org/article/39066cfbf9da4bac8aa29d11c5369e48
Autor:
Theo Desigaux, Leo Comperat, Nathalie Dusserre, Marie-Laure Stachowicz, Malou Lea, Jean-William Dupuy, Anthony Vial, Michael Molinari, Jean-Christophe Fricain, François Paris, Hugo Oliveira
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 316-327 (2024)
Deciphering breast cancer treatment resistance remains hindered by the lack of models that can successfully capture the four-dimensional dynamics of the tumor microenvironment. Here, we show that microextrusion bioprinting can reproducibly generate d
Externí odkaz:
https://doaj.org/article/b7d643e9eb374581aa8eb6438ce2e576
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 6, Pp 448-454 (2024)
ObjectiveTo explore the status of knowledge graph-based research into breast cancer microenvironment and to predict future research hotspots. MethodsThe literature related to breast cancer microenvironment in recent 20 years was retrieved from CNKI a
Externí odkaz:
https://doaj.org/article/0285b9d87e4e4cee9d0b6bef02e8502c
Autor:
Madison R. Pickett, Yuan-I Chen, Mohini Kamra, Sachin Kumar, Nikhith Kalkunte, Gabriella P. Sugerman, Kelsey Varodom, Manuel K. Rausch, Janet Zoldan, Hsin-Chin Yeh, Sapun H. Parekh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract The extracellular matrix (ECM) is a dynamic and complex microenvironment that modulates cell behavior and cell fate. Changes in ECM composition and architecture have been correlated with development, differentiation, and disease progression
Externí odkaz:
https://doaj.org/article/d87cd75796ac42b7bdc9800124804eef
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-6 (2024)
Abstract Background Cancer tissues contain a wide variety of immune cells that play critical roles in suppressing or promoting tumor progression. Macrophages are one of the most predominant populations in the tumor microenvironment and are composed o
Externí odkaz:
https://doaj.org/article/9912d2d95e9f4fbbb3ee8af65884dd82
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Liver cancer is a major global health concern, ranking among the top causes of cancer-related deaths worldwide. Despite advances in medical research, the prognosis for liver cancer remains poor, largely due to the inherent limitations of current ther
Externí odkaz:
https://doaj.org/article/0473331ddc5f43fbb465e4f35f2ee05d
Autor:
Maria Carmen Leiva, Anna Gustafsson, Elena Garre, Anders Ståhlberg, Anikó Kovács, Khalil Helou, Göran Landberg
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background The tumor microenvironment clearly influences cancer progressing properties but less is known about how individual cancer microenvironments potentially moderate cancer treatment effects. By cultivating and treating cancer cell lin
Externí odkaz:
https://doaj.org/article/41fdf1298b28424aad7fdf8966ef5a49
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 6, Pp 1133-1148 (2023)
Acid–base homeostasis is a fundamental property of living cells, and its persistent disruption in human cells can lead to a wide range of diseases. In this study, we conducted a computational modeling analysis of transcriptomic data of 4750 human t
Externí odkaz:
https://doaj.org/article/45ce346aa250484799ceaf38fbcb7f5e
Autor:
Tetta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundOur earlier research revealed that the secreted lysyl oxidase-like 4 (LOXL4) that is highly elevated in triple-negative breast cancer (TNBC) acts as a catalyst to lock annexin A2 on the cell membrane surface, which accelerates invasive outg
Externí odkaz:
https://doaj.org/article/4ed9034638704304a664180937894550
Publikováno v:
Biomimetics, Vol 9, Iss 5, p 306 (2024)
Cancer vasculogenesis is a pivotal focus of cancer research and treatment given its critical role in tumor development, metastasis, and the formation of vasculogenic microenvironments. Traditional approaches to investigating cancer vasculogenesis fac
Externí odkaz:
https://doaj.org/article/0cc932ce3d874b549841afa0f781cd51