Síntesis y funcionalización de (hetero)árenos mediante reacciones catalizadas por paladio o reducción de sulfóxidos: un enfoque hacia la obtención de 2-alquilbenzofuranos y otras moléculas de interés biológico

Autor: Mahecha Mahecha, Camilo Andres

Publikováno v: Séneca: repositorio Uniandes
Universidad de los Andes
instacron:Universidad de los Andes

Este documento presenta los resultados experimentales más relevantes de la investigación realizada en el Laboratorio de Síntesis Orgánica, Bio y Organocatálisis del Departamento de Química de la Universidad de los Andes bajo la dirección del D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::f4247ba3f0caeeff1322c981502abbba

Caracterización funcional del canal de potasio activado por calcio de conductancia intermedia (KCa3.1) en el endotelio de la córnea en condiciones fisiológicas y en ambientes hiperglúcidos

Autor: Amador-Munoz, Diana Patricia

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Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

La córnea es el lente que protege la superficie anterior del ojo y su transparencia es clave para permitir la visión. Esta característica en gran medida está determinada por la actividad de las células de su capa más profunda, el endotelio corn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7d3be579f186636b5cb2747a8a3e51

Computational analysis of 12 mutations in the potassium channel KCNQ2

Autor: Razquin Lizarraga, Amaia

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC

[EN]: In this work a computational analysis of 12 mutations in the potassium channel KCNQ2 is done. For that purpose the macromolecular modeling software Rosetta is used. This mutations are relevant because they are related to a rare epilepsy disorde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1908969a91dc6ce4a17901a547cd501f
http://hdl.handle.net/10810/54319

Determinación electrofisiológica de la presencia de la corriente GIRK en neuronas aferentes vestibulares

Autor: Juárez Mora, Francisco

Publikováno v: Benemérita Universidad Autónoma de Puebla
BUAP
Repositorio Institucional de Acceso Abierto RIAA-BUAP

“El vértigo, el mareo y el desequilibrio son los principales síntomas de los trastornos vestibulares. En niños con problemas de fijación de la mirada asociado con disfunción vestibular pueden llevar a problemas de lectura y repercutir sobre su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::2b4eac3c105bb2ea0d970696df99c5fc

Ácido araquidónico: estudio biofísico y funcional de su efecto sobre el canal de K+ de alta conductancia dependiente de calcio y voltaje (BK) asociado a la subunidad β1

Autor: Melisa Moncada

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

En este trabajo de Tesis doctoral investigamos en profundidad el mecanismo de acción del ácido araquidónico (AA) sobre el canal de potasio BK asociado a la subunidad β1. Demostramos que el AA es capaz de activar al canal BK cuando el mismo se enc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d264976d7658cf6be88878cb8f2187c
https://doi.org/10.35537/10915/115445