Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site

Autor: Sheehan, Scott M., Mest, Hans-Juergen, Watson, Brian M., Klimkowski, Valentine J., Timm, David E., Cauvin, Annick, Parsons, Stephen H., Shi, Qing, Canada, Emily J., Wiley, Michael R., Ruehter, Gerd, Evers, Britta, Petersen, Soenke, Blaszczak, Larry C., Pulley, Shon R., Margolis, Brandon J., Wishart, Graham N., Renson, Beatrice, Hankotius, Dirk, Mohr, Michael, Zechel, Johann-Christian, Michael Kalbfleisch, J., Dingess-Hammond, Elizabeth A., Boelke, Andre, Weichert, Andreas G.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2007 17(6):1765-1768

Synthesis and structure–activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor

Autor: Shi, Qing, Ornstein, Paul L., Briner, Karin, Richardson, Timothy I., Arnold, Macklin B., Backer, Ryan T., Buckmaster, Jennifer L., Canada, Emily J., Doecke, Christopher W., Hertel, Larry W., Honigschmidt, Nick, Hsiung, Hansen M., Husain, Saba, Kuklish, Steve L., Martinelli, Michael J., Mullaney, Jeffrey T., O’Brien, Thomas P., Reinhard, Matt R., Rothhaar, Roger, Shah, Jikesh, Wu, Zhipei, Xie, Chaoyu, Zgombick, John M., Fisher, Matthew J.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2006 16(9):2341-2346

Design and Synthesis of Dual Peroxisome Proliferator-Activated Receptors and Agonists as Novel Euglycemic Agents with a Reduced Weight Gain Profile

Autor: Xu, Yanping, J. Etgen, Garret, L. Broderick, Carol, Canada, Emily, Gonzalez, Isabel, Lamar, Jason, Montrose-Rafizadeh, Chahrzad, A. Oldham, Brian, J. Osborne, John, Xie, Chaoyu, Shi, Qing, L. Winneroski, Leonard, York, Jeremy, Yumibe, Nathan, Zink, Richard, Mantlo, Nathan

Publikováno v: Journal of Medicinal Chemistry; September 2006, Vol. 49 Issue: 19 p5649-5652, 4p

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Reply to C.T. Matava et al.

Autor: Alexander S; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Kairalla JA; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Gupta S; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Hibbitts E; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Weisman H; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Anghelescu D; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Winick NJ; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Krull KR; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Salzer WL; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Burke MJ; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Gore L; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Devidas M; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Embry L; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Raetz EA; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Hunger SP; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Loh ML; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC., Hardy KK; Sarah Alexander, MD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; John A. Kairalla, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Sumit Gupta, MD, PhD, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; Emily Hibbitts, PhD, Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL; Hannah Weisman, BSc, Children's National Hospital, Washington, DC; Doralina Anghelescu, MD, Division of Anesthesiology, St Jude Children's Research Hospital, Memphis, TN; Naomi J. Winick, MD, Department of Pediatric Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Kevin R. Krull, PhD, Department of Psychology and Biobehavioral Sciences, St Jude Children's Research Hospital, Memphis, TN; Wanda L. Salzer, MD, Uniformed Services University, F. Edward Hebert School of Medicine, Bethesda, MD; Michael J. Burke, MD, Department of Pediatrics, The Medical College of Wisconsin Inc, Milwaukee, WI; Lia Gore, MD, Children's Hospital Colorado, University of Colorado, Aurora, CO; Meenakshi Devidas, PhD, Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Leanne Embry, PhD, University of Texas Health at San Antonio, San Antonio, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Stephen P. Hunger, MD, Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Mignon L. Loh, MD, The Ben Towne Center for Childhood Cancer Research and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA; and Kristina K. Hardy, PhD, Children's National Hospital, Washington, DC.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Oct 10; Vol. 42 (29), pp. 3507-3509. Date of Electronic Publication: 2024 Jul 24.