Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models

Autor: Morera-Díaz, Y., Canaán-Haden, C., Sánchez-Ramírez, J., Bequet-Romero, M., Gonzalez-Moya, I., Martínez, R., Falcón, V., Palenzuela, D., Ayala-Ávila, M., Gavilondo, J.V.

Publikováno v: In Cancer Letters 1 May 2023 561

8P Modulating tumor microenvironment using a VEGF active immunotherapeutic approach in gastrointestinal tumors: Beyond angiogenesis modulation

Autor: Bequet-Romero, M., Morera, Y., Hernández-Bernal, F., Canaan-Haden, C., Selman-Housein, K-H., González-Moya, I., Sanchez-Ramirez, J., Martín-Bauta, Y., de la Torre-Santos, A., Ayala, M.

Publikováno v: In Annals of Oncology October 2023 34 Supplement 2:S189-S189

HeberNasvac, a Therapeutic Vaccine for Chronic Hepatitis B, Stimulates Local and Systemic Markers of Innate Immunity: Potential Use in SARS-CoV-2 Postexposure Prophylaxis.

Autor: Fleites YA; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Aguiar J; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Cinza Z; Department of Vaccines, Clinical Trials Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Bequet M; Department of Pharmaceuticals, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Marrero E; Department of Quality Control Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Vizcaíno M; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Esquivel I; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Diaz M; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Sin-Mayor A; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Garcia M; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Martinez SM; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Beato A; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Galarraga AG; Department of Clinical Trials, Luis Diaz Soto Hospital, Havana, Cuba., Mendoza-Mari Y; Department of Pharmaceuticals, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Valdés I; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., García G; Department of Quality Control Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Lemos G; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., González I; Department of Pharmaceuticals, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Canaán-Haden C; Department of Pharmaceuticals, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Figueroa N; Department of Vaccines, Clinical Trials Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Oquendo R; Department of Vaccines, Clinical Trials Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Akbar SM; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan., Mahtab MA; Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh., Uddin MH; Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh., Guillén GE; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Muzio VL; Department of Vaccines, Clinical Trials Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Pentón E; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Aguilar JC; Department of Vaccines, Biomedical Research Direction, Center for Genetic Engineering and Biotechnology, Havana, Cuba.

Publikováno v: Euroasian journal of hepato-gastroenterology [Euroasian J Hepatogastroenterol] 2021 Jul-Dec; Vol. 11 (2), pp. 59-70.