Výsledky vyhledávání - "Can-Can Yuan"

Akademický článek

Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis

Autor: Mei-Zi Wang, Jie Wang, Dong-Wei Cao, Yue Tu, Bu-Hui Liu, Can-Can Yuan, Huan Li, Qi-Jun Fang, Jia-Xin Chen, Yan Fu, Bing-Ying Wan, Zi-Yue Wan, Yi-Gang Wan, Guo-Wen Wu

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Background: Fucoidan (FPS) has been widely used to treat renal fibrosis (RF) in patients with diabetic kidney disease (DKD); however, the precise therapeutic mechanisms remain unclear. Recently, research focusing on inflammation-derived podocyte pyro

Externí odkaz: https://doaj.org/article/e381d36e183c40d484336a4e994eea96

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Akademický článek

Inhibition of Renal Tubular Epithelial Mesenchymal Transition and Endoplasmic Reticulum Stress-Induced Apoptosis with Shenkang Injection Attenuates Diabetic Tubulopathy

Autor: Wen-Wen Wang, Ying-Lu Liu, Mei-Zi Wang, Huan Li, Bu-Hui Liu, Yue Tu, Can-Can Yuan, Qi-Jun Fang, Jia-Xin Chen, Jie Wang, Yan Fu, Zi-Yue Wan, Yi-Gang Wan, Wei Wu

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Background: The proximal renal tubule plays a critical role in diabetic kidney disease (DKD) progression. Early glomerular disease in DKD triggers a cascade of injuries resulting in renal tubulointerstitial disease. These pathophysiological responses

Externí odkaz: https://doaj.org/article/6e5a17a3b367498cb8b8c6b3e2d83cd2

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Akademický článek

Fucoidan Ameliorates Renal Injury-Related Calcium-Phosphorus Metabolic Disorder and Bone Abnormality in the CKD–MBD Model Rats by Targeting FGF23-Klotho Signaling Axis

Autor: Bu-Hui Liu, Fee-Lan Chong, Can-Can Yuan, Ying-Lu Liu, Hai-Ming Yang, Wen-Wen Wang, Qi-Jun Fang, Wei Wu, Mei-Zi Wang, Yue Tu, Zi-Yue Wan, Yi-Gang Wan, Guo-Wen Wu

Publikováno v: Frontiers in Pharmacology, Vol 11 (2021)

Background: Recently, chronic kidney disease (CKD)-mineral and bone disorder (MBD) has become one of common complications occurring in CKD patients. Therefore, development of a new treatment for CKD–MBD is very important in the clinic. In China, Fu

Externí odkaz: https://doaj.org/article/2389f7e96d774fad892e1e1ff0c5d5d5

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Akademický článek

Total Flavones of Abelmoschus manihot Remodels Gut Microbiota and Inhibits Microinflammation in Chronic Renal Failure Progression by Targeting Autophagy-Mediated Macrophage Polarization

Autor: Yue Tu, Qi-Jun Fang, Wei Sun, Bu-Hui Liu, Ying-Lu Liu, Wei Wu, Hong-Yun Yee, Can-Can Yuan, Mei-Zi Wang, Zi-Yue Wan, Ren-Mao Tang, Yi-Gang Wan, Hai-Tao Tang

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

BackgroundRecently, progression of chronic renal failure (CRF) has been closely associated with gut microbiota dysbiosis and intestinal metabolite-derived microinflammation. In China, total flavones of Abelmoschus manihot (TFA), a component of Abelmo

Externí odkaz: https://doaj.org/article/c34f31aa8d914b58a86a55db6e6e17e4

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Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

Autor: Wei Wu, Xian‐Jie Meng, Bing‐Ying Wan, Qi‐Jun Fang, Ying‐Lu Liu, Jie Wang, Yan Fu, Can‐Can Yuan, Mei‐Zi Wang, Fee‐Lan Chong, Yi‐Gang Wan, Shan‐Mei Shen

Publikováno v: Anatomical record (Hoboken, N.J. : 2007)REFERENCES.

Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1881990b261676005fdcad40af12f43
https://pubmed.ncbi.nlm.nih.gov/34910381

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[Effects and mechanisms of Supplemented Gegen Qinlian Decoction Formula against podocyte pyroptosis and insulin resistance in model rats with diabetic kidney disease]

Autor: Mei-Zi, Wang, Li-Jun, Yue, Yi-Gang, Wan, Huang, Huang, Wei, Wu, Yue, Tu, Bu-Hui, Liu, Qi-Jun, Fang, Can-Can, Yuan, Jie, Wang, Huan, Li, Zi-Yue, Wan

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 46(17)

This study explored the in vivo effects and mechanisms of the modern classical prescription Supplemented Gegen Qinlian Decoction Formula(SGDF) against diabetic kidney disease(DKD). Sixty rats were randomly divided into the normal group, model group,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::866ed970f8c5ca8a18f3fb85f9f3db31
https://pubmed.ncbi.nlm.nih.gov/34581052

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[Exploring molecular mechanisms of fucoidan in improving human proximal renal tubular epithelial cells aging by targeting autophagy signaling pathways]

Autor: Qi-Jun, Fang, Jian-Jing, Liu, Yi-Gang, Wan, Bu-Hui, Liu, Yue, Tu, Wei, Wu, Ying-Lu, Liu, Wen-Wen, Wang, Mei-Zi, Wang, Hong-Yun, Yee, Can-Can, Yuan, Fee-Lan, Chong

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 45(24)

Fucoidan(FPS) is an effective component of the Chinese patent medicine named Haikun Shenxi, which treats schronic renal failure in clinics, and has the potential anti-aging effects. However, it is still unclear whether FPS can improve renal aging, es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f80c4ae8f75fe95f236eb89cb3ad6795
https://pubmed.ncbi.nlm.nih.gov/33496141

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