Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Can Bruce"'
Autor:
Christopher M. Colangelo, Mark Shifman, Kei-Hoi Cheung, Kathryn L. Stone, Nicholas J. Carriero, Erol E. Gulcicek, TuKiet T. Lam, Terence Wu, Robert D. Bjornson, Can Bruce, Angus C. Nairn, Jesse Rinehart, Perry L. Miller, Kenneth R. Williams
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 13, Iss 1, Pp 25-35 (2015)
We report a significantly-enhanced bioinformatics suite and database for proteomics research called Yale Protein Expression Database (YPED) that is used by investigators at more than 300 institutions worldwide. YPED meets the data management, archiva
Externí odkaz:
https://doaj.org/article/dcedb7098db74bf2901e8509793789af
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1852-1858 (2004)
We reported that phospholipid transfer protein (PLTP) deficiency decreased atherosclerosis in mouse models. Because the decreased atherosclerosis was accompanied by a significant decrease in plasma HDL levels, we examined the properties of PLTP knock
Externí odkaz:
https://doaj.org/article/dec0c3f1d6594b2383f59088e5cc5c54
Autor:
Heidi Rath Hope, Deborah Heuvelman, Kevin Duffin, Christine Smith, Jeffery Zablocki, Roger Schilling, Shridhar Hegde, Len Lee, Bryan Witherbee, Mark Baganoff, Can Bruce, Alan R. Tall, Elaine Krul, Kevin Glenn, Daniel T. Connolly
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 10, Pp 1604-1614 (2000)
SC-71952, a substituted analog of dithiobisnicotinic acid dimethyl ester, was identified as a potent inhibitor of cholesteryl ester transfer protein (CETP). When tested in an in vitro assay, the concentration of SC-71952 required for half-maximal inh
Externí odkaz:
https://doaj.org/article/cc5033ac3088478fbe63f90dab676d71
Autor:
Shucun Qin, Koichi Kawano, Can Bruce, Min Lin, Charles Bisgaier, Alan R. Tall, Xian-cheng Jiang
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 269-276 (2000)
Phospholipid transfer protein gene knock-out (Pltp KO) mice have defective transfer of very low density lipoprotein (VLDL) phospholipids into high density lipoprotein (HDL) and markedly decreased HDL levels (Jiang et al. 1999. J. Clin. Invest. 103: 9
Externí odkaz:
https://doaj.org/article/4a565001cd124579aca542b316e26698
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 5, Pp 1071-1078 (1998)
Plasma triglyceride (TG) levels are inversely related to HDL-cholesterol levels and subjects with high TG and low HDL cholesterol have increased coronary heart disease (CHD) risk. Plasma cholesteryl ester transfer protein (CETP) transfers cholesteryl
Externí odkaz:
https://doaj.org/article/c7b801b9c74b43c79ff23e26cb1e3a83
Autor:
Gregory M. Miller, J. Austin Ellis, Rangaprasad Sarangarajan, Amay Parikh, Leonardo O. Rodrigues, Can Bruce, Nischal Mahaveer Chand, Steven R. Smith, Kris Richardson, Raymond Vazquez, Michael A. Kiebish, Chandran Haneesh, Elder Granger, Judy Holtz, Jacob Hinkle, Niven R. Narain, Bret Goodpaster, Jeremy C. Smith, Daniel S. Lupu
Publikováno v:
Drugs - real world outcomes. 9(3)
The COVID-19 pandemic generated a massive amount of clinical data, which potentially hold yet undiscovered answers related to COVID-19 morbidity, mortality, long-term effects, and therapeutic solutions.The objectives of this study were (1) to identif
Autor:
Can Bruce, Raymond Vazquez, Nischal Mahaveer Chand, Steven R. Smith, Kris Richardson, Jacob Hinkle, Rangaprasad Sarangarajan, Elder Granger, Niven R. Narain, Daniel S. Lupu, Haneesh Chandran, Leonardo O. Rodrigues, Judy Holtz, Austin J Ellis, Bret H. Goodpaster, Jeremy C. Smith, Gregory M Miller, Amay Parikh, Michael A. Kiebish
ObjectiveThe COVID-19 pandemic generated a massive amount of clinical data, which potentially holds yet undiscovered answers related to COVID-19 morbidity, mortality, long term effects, and therapeutic solutions. The objective of this study was to ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d21b921016d72403ed85a18d580513
https://doi.org/10.1101/2021.10.05.21264578
https://doi.org/10.1101/2021.10.05.21264578
Autor:
Shiva Kazerounian, Mollie O'Hara, Arcan Guven, Kashni Grover, Nicole Pellegrino, Kayleigh Gray, Can Bruce, Gregory M. Miller, Maria-Dorothea Nastke, Michael A. Kiebish, Eric M. Grund, Rangaprasad Sarangarajan, Niven R. Narain, Stephane Gesta, Vivek K. Vishnudas
Publikováno v:
Cancer Research. 82:5320-5320
Gastric cancer is difficult to treat and exhibits poor survival with current therapies (five-year survival for all stages is 32% and 5% for metastatic gastric cancer) demonstrating a clear unmet clinical need. UBE2K was identified as a drug target fr
Autor:
Lawrence Recht, Niven R. Narain, Valerie Bussberg, Greg M Miller, Richard Searfoss, Kennedy Ofori-Mensa, Punit P. Shah, Vladimir Tolstikov, Rangaprasad Sarangarajan, Elder Granger, Seema Nagpal, Can Bruce, Michael A. Kiebish, Leonardo O. Rodrigues, Bennett Greenwood
Publikováno v:
Journal of Clinical Oncology. 39:2059-2059
2059 Background: BPM 31510-IV is a drug-lipid conjugate nanodispersion containing oxidized Coenzyme Q10 (CoQ10) in clinical development for glioblastoma multiforme (GBM). In a recently concluded Phase 1 study of BPM 31510-IV (NCT03020602), in additio
Autor:
Kei-Hoi Cheung, Erol E. Gulcicek, Perry L. Miller, Jesse Rinehart, Terence Wu, Kenneth R. Williams, TuKiet T. Lam, Mark A. Shifman, Kathryn L. Stone, Angus C. Nairn, Can Bruce, Robert D. Bjornson, Christopher M. Colangelo, Nicholas Carriero
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 13, Iss 1, Pp 25-35 (2015)
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics
We report a significantly-enhanced bioinformatics suite and database for proteomics research called Yale Protein Expression Database (YPED) that is used by investigators at more than 300 institutions worldwide. YPED meets the data management, archiva