A kinesin-based approach for inducing chromosome-specific mis-segregation in human cells

Autor: Truong, My Anh, Cané-Gasull, Paula, de Vries, Sippe G, Nijenhuis, Wilco, Wardenaar, René, Kapitein, Lukas C, Foijer, Floris, Lens, Susanne

Various cancer types exhibit characteristic and recurrent aneuploidy patterns. The origins of these cancer type-specific karyotypes are still unknown, partly because introducing or eliminating specific chromosomes in human cells still poses a challen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::06ea918260e5b699ebd8b95469fe097a
https://dspace.library.uu.nl/handle/1874/428454

A kinesin-based approach for inducing chromosome-specific mis-segregation in human cells.

Autor: Truong MA; Oncode Institute, Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Cané-Gasull P; Oncode Institute, Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., de Vries SG; Oncode Institute, Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Nijenhuis W; Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, Utrecht, The Netherlands., Wardenaar R; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Kapitein LC; Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, Utrecht, The Netherlands., Foijer F; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Lens SM; Oncode Institute, Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Publikováno v: The EMBO journal [EMBO J] 2023 May 15; Vol. 42 (10), pp. e111559. Date of Electronic Publication: 2023 Apr 11.