Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Camryn L. Johnson"'
Publikováno v:
Am J Physiol Heart Circ Physiol
Inflammation caused by infiltrating macrophages and T cells promotes plaque growth in atherosclerosis. Cadherin-11 (CDH11) is a cell-cell adhesion protein implicated in several fibrotic and inflammatory diseases. Much of the research on CDH11 concern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd35518b82f6d50e01ec00119f3b427
https://doi.org/10.1152/ajpheart.00263.2021
https://doi.org/10.1152/ajpheart.00263.2021
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Celecoxib use is associated with diagnosis of aortic stenosis in analysis of electronic medical records. • Celecoxib treatment increases dystrophic calcification of aortic valve interstitial cells in vitro. • D
Highlights • Celecoxib use is associated with diagnosis of aortic stenosis in analysis of electronic medical records. • Celecoxib treatment increases dystrophic calcification of aortic valve interstitial cells in vitro. • D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c4e92d400d6ce868c4287bfc62ae2a
https://doi.org/10.1016/j.jacbts.2018.12.003
https://doi.org/10.1016/j.jacbts.2018.12.003
Autor:
W. David Merryman, Camryn L. Johnson
Publikováno v:
J Biomech
Calcific aortic valve disease (CAVD) is a condition causing stiffening of the aortic valve, impeding cardiac function and resulting in significant morbidity worldwide. CAVD is thought to be driven by the persistent activation of the predominant cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372471d86fa92991bb995dff6a7071ca
https://doi.org/10.1016/j.jbiomech.2021.110253
https://doi.org/10.1016/j.jbiomech.2021.110253
Autor:
W. David Merryman, Camryn L. Johnson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
During the cardiac cycle, the ventricular side of the aortic valve (ventricularis) is exposed to high shear pulsatile flow, while the aortic side (fibrosa) is exposed to low shear recirculatory flow. The two sides have different transcriptional profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b9d61fa99039dfd461d4d39de641d4
https://doi.org/10.1161/atvb.36.suppl_1.154
https://doi.org/10.1161/atvb.36.suppl_1.154
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Objectives: Specialized endocardial cells are responsible for the development of heart valves in utero . During a highly regulated morphogenetic process, these endocardial cells undergo endothelial-to-mesenchymal transformation (EMT) to become valve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4613f4f88055ddb86c529340e3e50749
https://doi.org/10.1161/atvb.36.suppl_1.60
https://doi.org/10.1161/atvb.36.suppl_1.60