Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19.

Autor: Murdocca M; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., Andrade Santos-Filho O; Center of Health Sciences Laboratory of Molecular Modelling & Computational Strutural Biology Cidade Universitária, Federal University of Rio de Janeiro IPPN, Av. Carlos Chagas Filho373, Bloco H, Rio de Janeiro, 21941-599, RJ, Brazil., De Masi C; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., Dos Santos Rodrigues E; Center of Health Sciences Laboratory of Molecular Modelling & Computational Strutural Biology Cidade Universitária, Federal University of Rio de Janeiro IPPN, Av. Carlos Chagas Filho373, Bloco H, Rio de Janeiro, 21941-599, RJ, Brazil., Campos de Souza CV; Center of Health Sciences Laboratory of Molecular Modelling & Computational Strutural Biology Cidade Universitária, Federal University of Rio de Janeiro IPPN, Av. Carlos Chagas Filho373, Bloco H, Rio de Janeiro, 21941-599, RJ, Brazil., De Santis R; Department of Public Health and Infectious Diseases, University of Rome Sapienza, Rome, Italy.; Defence Institute for Biomedical Sciences, Rome, 00184, Italy., Amatore D; Defence Institute for Biomedical Sciences, Rome, 00184, Italy., Latini A; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., Schipani R; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., di Rienzo Businco L; Otorhinolaryngology Department, Institute of Sport Medicine and Science CONI, Rome, Italy., Brandimarte B; Electronic Measurements Physics Department, Sapienza University, Rome, Italy., Grilli G; Defence Institute for Biomedical Sciences, Rome, 00184, Italy., Huang TL; Formerly Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA, 70125, USA., Mayence AS; Formerly Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA, 70125, USA., Lista F; Defence Institute for Biomedical Sciences, Rome, 00184, Italy., Duranti A; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, 61029, Italy., Sangiuolo F; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy. sangiuolo@med.uniroma2.it., Vanden Eynde JJ; Formerly Department of Organic Chemistry (FS), University of Mons-UMONS, 1 place du Parc, Mons, 7000, Belgium., Novelli G; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

Publikováno v: Biology direct [Biol Direct] 2024 Oct 16; Vol. 19 (1), pp. 93. Date of Electronic Publication: 2024 Oct 16.