A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis.

Autor: Pradella D; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', Consiglio Nazionale delle Ricerche, Pavia, Italy.; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy., Deflorian G; IFOM, The FIRC Institute of Molecular Oncology, Milan, Italy.; Cogentech, Società Benefit, Milan, Italy., Pezzotta A; Department of Medical Biotechnology and Translational Medicine, University of Milan-LITA, Segrate, Italy., Di Matteo A; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', Consiglio Nazionale delle Ricerche, Pavia, Italy., Belloni E; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', Consiglio Nazionale delle Ricerche, Pavia, Italy., Campolungo D; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', Consiglio Nazionale delle Ricerche, Pavia, Italy.; IRCCS San Raffaele Scientific Institute, Division of Genetics and Cell Biology, Milan, Italy., Paradisi A; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Bugatti M; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Vermi W; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Campioni M; The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Pavia, Italy., Chiapparino A; The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.; Heidelberg University Biochemistry Center (BZH), INF 328, Heidelberg, Germany., Scietti L; The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Pavia, Italy., Forneris F; The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Pavia, Italy., Giampietro C; IFOM, The FIRC Institute of Molecular Oncology, Milan, Italy.; Swiss Federal Laboratories for Materials Science and Technology, Experimental Continuum Mechanics EMPA, Dübendorf, Switzerland., Volf N; Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), AREA Science Park, Padriciano 99, Trieste, Italy., Rehman M; Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), AREA Science Park, Padriciano 99, Trieste, Italy.; Yale University School of Medicine, Section of Nephrology, New Haven, CT, USA., Zacchigna S; Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), AREA Science Park, Padriciano 99, Trieste, Italy.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Paronetto MP; Laboratory of Molecular and Cellular Neurobiology, IRCCS Santa Lucia Foundation, Rome, Italy.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Pistocchi A; Department of Medical Biotechnology and Translational Medicine, University of Milan-LITA, Segrate, Italy., Eichmann A; Cardiovascular Research Center, Yale University School of Medicine, Department of Internal Medecine Cardiology, New Haven, CT, USA.; INSERM U970, Paris Center for Cardiovascular Research (PARCC), Paris, France.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA., Mehlen P; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Ghigna C; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', Consiglio Nazionale delle Ricerche, Pavia, Italy. Claudia.Ghigna@igm.cnr.it.

Publikováno v: Nature communications [Nat Commun] 2021 Aug 11; Vol. 12 (1), pp. 4872. Date of Electronic Publication: 2021 Aug 11.

Acute myeloid leukemia cells adhere to bone marrow and acquire chemoresistance by downregulating UNC5B expression.

Autor: Teng Teng, Liping Ren, Jilong Xiao, Zhiyu Shi, Lanbo Li, Chunhong Song

Publikováno v: Frontiers in Oncology; 2024, p1-12, 12p

Food Toxicity of Mycotoxin Citrinin and Molecular Mechanisms of Its Potential Toxicity Effects through the Implicated Targets Predicted by Computer-Aided Multidimensional Data Analysis.

Autor: Zargar, Seema¹ (AUTHOR) szargar@ksu.edu.sa, Wani, Tanveer A.² (AUTHOR)

Publikováno v: Life (2075-1729). Apr2023, Vol. 13 Issue 4, p880. 12p.

Neogenin suppresses tumor progression and metastasis via inhibiting Merlin/YAP signaling.

Autor: Hu, Xiaohan, Li, Li, Li, Fang, Yang, Yuan, An, Jingnan, Zhou, Xinghua, Zhang, Rui, Shi, Lingli, Zhao, He, Wang, Jian, Hu, Yizhou, Xu, Yunyun

Publikováno v: Cell Death Discovery; 2/6/2023, Vol. 9 Issue 1, p1-13, 13p

Comprehensive analysis of spliceosome genes and their mutants across 27 cancer types in 9070 patients: clinically relevant outcomes in the context of 3P medicine.

Autor: Ye, Zhen, Bing, Aiying, Zhao, Shulian, Yi, Shuying, Zhan, Xianquan

Publikováno v: EPMA Journal; 5/10/2022, Vol. 13 Issue 1, p335-350, 16p