Ca V 1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling.

Autor: Pelizzari S; Institute of Physiology, Department of Physiology and Medical Biophysics, Medical University Innsbruck, 6020, Innsbruck, Austria., Heiss MC; Institute of Physiology, Department of Physiology and Medical Biophysics, Medical University Innsbruck, 6020, Innsbruck, Austria., Fernández-Quintero ML; Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., El Ghaleb Y; Institute of Physiology, Department of Physiology and Medical Biophysics, Medical University Innsbruck, 6020, Innsbruck, Austria., Liedl KR; Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Tuluc P; Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, 6020, Innsbruck, Austria., Campiglio M; Institute of Physiology, Department of Physiology and Medical Biophysics, Medical University Innsbruck, 6020, Innsbruck, Austria., Flucher BE; Institute of Physiology, Department of Physiology and Medical Biophysics, Medical University Innsbruck, 6020, Innsbruck, Austria. bernhard.e.flucher@i-med.ac.at.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 28; Vol. 15 (1), pp. 7440. Date of Electronic Publication: 2024 Aug 28.

STAC3 determines the slow activation kinetics of Ca V 1.1 currents and inhibits its voltage-dependent inactivation.

Autor: Tuinte WE; Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria., Török E; Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria., Mahlknecht I; Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria., Tuluc P; Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria., Flucher BE; Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria., Campiglio M; Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria.

Publikováno v: Journal of cellular physiology [J Cell Physiol] 2022 Nov; Vol. 237 (11), pp. 4197-4214. Date of Electronic Publication: 2022 Sep 26.

Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1.

Autor: El Ghaleb Y; Institute of Physiology, Department of Physiology and Medical Physics, Medical University Innsbruck, Innsbruck, Austria., Ortner NJ; Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria., Posch W; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria., Fernández-Quintero ML; Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Tuinte WE; Institute of Physiology, Department of Physiology and Medical Physics, Medical University Innsbruck, Innsbruck, Austria., Monteleone S; Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Draheim HJ; Boehringer Ingelheim Pharma GmbH & Co KG, CNS Research, Biberach an der Riss, Germany., Liedl KR; Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Wilflingseder D; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria., Striessnig J; Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria., Tuluc P; Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria., Flucher BE; Institute of Physiology, Department of Physiology and Medical Physics, Medical University Innsbruck, Innsbruck, Austria., Campiglio M; Institute of Physiology, Department of Physiology and Medical Physics, Medical University Innsbruck, Innsbruck, Austria.

Publikováno v: The Journal of general physiology [J Gen Physiol] 2022 Sep 05; Vol. 154 (9). Date of Electronic Publication: 2022 Mar 29.

Apoptosis induction by trastuzumab: possible role of the core biopsy intervention.

Autor: Ménard S, Pupa SM, Campiglio M, Balsari A, Fagnoni F, Costa A, Tagliabue E

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2005 Oct 01; Vol. 23 (28), pp. 7238-40.

Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.

Autor: Yang ZF; Department of Biochemistry and Molecular Biology, The Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Panwar P; Department of Biochemistry and Molecular Biology, The Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., McFarlane CR; Department of Biochemistry and Molecular Biology, The Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Tuinte WE; Institute of Physiology, Medical University of Innsbruck, Innsbruck, 6020 Austria., Campiglio M; Institute of Physiology, Medical University of Innsbruck, Innsbruck, 6020 Austria., Van Petegem F; Department of Biochemistry and Molecular Biology, The Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 08; Vol. 119 (10), pp. e2120416119. Date of Electronic Publication: 2022 Mar 01.