Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Campbell W Gourlay"'
Autor:
Emily Saintas, Liam Abrahams, Gulshan T Ahmad, Anu-Oluwa M Ajakaiye, Abdulaziz S H A M AlHumaidi, Candice Ashmore-Harris, Iain Clark, Usha K Dura, Carine N Fixmer, Chinedu Ike-Morris, Mireia Mato Prado, Danielle Mccullough, Shishir Mishra, Katia M U Schöler, Husne Timur, Maxwell D C Williamson, Markella Alatsatianos, Basma Bahsoun, Edith Blackburn, Catherine E Hogwood, Pamela E Lithgow, Michelle Rowe, Lyto Yiangou, Florian Rothweiler, Jindrich Cinatl, Richard Zehner, Anthony J Baines, Michelle D Garrett, Campbell W Gourlay, Darren K Griffin, William J Gullick, Emma Hargreaves, Mark J Howard, Daniel R Lloyd, Jeremy S Rossman, C Mark Smales, Anastasios D Tsaousis, Tobias von der Haar, Mark N Wass, Martin Michaelis
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172140 (2017)
The formation of acquired drug resistance is a major reason for the failure of anti-cancer therapies after initial response. Here, we introduce a novel model of acquired oxaliplatin resistance, a sub-line of the non-MYCN-amplified neuroblastoma cell
Externí odkaz:
https://doaj.org/article/ef8bcb9439b04f71b952d9ed30ce9beb
Autor:
Rosana Alves, Campbell W. Gourlay
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/980a75e615314993880997ec9d1c615e
Autor:
Jack Davis, Thorsten Meyer, Martin Smolnig, Daniel G.J. Smethurst, Lisa Neuhaus, Jonas Heyden, Filomena Broeskamp, Elizabeth S.M. Edrich, Oskar Knittelfelder, Dagmar Kolb, Tobias von der Haar, Campbell W. Gourlay, Patrick Rockenfeller
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107539- (2023)
Summary: The dynamic nature of the actin cytoskeleton is required to coordinate many cellular processes, and a loss of its plasticity has been linked to accelerated cell aging and attenuation of adaptive response mechanisms. Cofilin is an actin-bindi
Externí odkaz:
https://doaj.org/article/be50f411dace449ba5f7ff725e47e81c
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1619 (2023)
The small GTPase Ras plays an important role in connecting external and internal signalling cues to cell fate in eukaryotic cells. As such, the loss of RAS regulation, localisation, or expression level can drive changes in cell behaviour and fate. Po
Externí odkaz:
https://doaj.org/article/7e1a989b9cc94e1d86981d853082f9bd
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract C. albicans is the predominant human fungal pathogen and frequently colonises medical devices, such as voice prostheses, as a biofilm. It is a dimorphic yeast that can switch between yeast and hyphal forms in response to environmental cues,
Externí odkaz:
https://doaj.org/article/6684d235fbea46498d7042094ef24164
Autor:
Jing Li, Mark Rinnerthaler, Johannes Hartl, Manuela Weber, Thomas Karl, Hannelore Breitenbach-Koller, Michael Mülleder, Jakob Vowinckel, Hans Marx, Michael Sauer, Diethard Mattanovich, Özge Ata, Sonakshi De, Gregor P. Greslehner, Florian Geltinger, Bill Burhans, Chris Grant, Victoria Doronina, Meryem Ralser, Maria Karolin Streubel, Christian Grabner, Stefanie Jarolim, Claudia Moßhammer, Campbell W. Gourlay, Jiri Hasek, Paul J. Cullen, Gianni Liti, Markus Ralser, Michael Breitenbach
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4637-4648 (2020)
Externí odkaz:
https://doaj.org/article/ca33687db4764dc69874932343b3fe4a
Autor:
Filomena Broeskamp, Elizabeth S. M. Edrich, Oskar Knittelfelder, Lisa Neuhaus, Thorsten Meyer, Jonas Heyden, Lukas Habernig, Florian Kreppel, Campbell W. Gourlay, Patrick Rockenfeller
Publikováno v:
Cells, Vol 10, Iss 9, p 2416 (2021)
Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular mater
Externí odkaz:
https://doaj.org/article/1a6f54ffecae44a8a599bd8710dcc9dc
Autor:
Lucian Duvenage, Louise A. Walker, Aleksandra Bojarczuk, Simon A. Johnston, Donna M. MacCallum, Carol A. Munro, Campbell W. Gourlay
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The human fungal pathogen Candida albicans requires respiratory function for normal growth, morphogenesis, and virulence. Mitochondria therefore represent an enticing target for the development of new antifungal strategies. This possibility
Externí odkaz:
https://doaj.org/article/d09b6a0106be494e92b07724b0b9b1ca
Autor:
Jeff W. Barclay, Claire E. Eyers, Alan Morgan, Kimberley Burrow, Richard Campion, Patricia Thomas, Philip Brownridge, Leanne Bloxam, Campbell W. Gourlay, Daniel R Pentland
Publikováno v:
Biochemical Journal
BIOCHEMICAL JOURNAL
BIOCHEMICAL JOURNAL
Dietary restriction (DR) has been shown to increase lifespan in organisms ranging from yeast to mammals. This suggests that the underlying mechanisms may be evolutionarily conserved. Indeed, upstream signalling pathways, such as TOR, are strongly lin
Autor:
Stefanie Jarolim, Hans Marx, Thomas Karl, Johannes Hartl, Gianni Liti, Jiri Hasek, Özge Ata, Manuela Weber, Bill Burhans, Maria Karolin Streubel, Gregor P Greslehner, Jing Li, Campbell W. Gourlay, Hannelore Breitenbach-Koller, Diethard Mattanovich, Paul J. Cullen, Florian Geltinger, Mark Rinnerthaler, Claudia Moßhammer, Jakob Vowinckel, Michael Mülleder, Michael Sauer, Michael Breitenbach, Chris M. Grant, Meryem Ralser, Sonakshi De, Christian Grabner, Markus Ralser, Victoria Doronina
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4637-4648 (2020)
G3: Genes|Genomes|Genetics
G3
G3, Genetics Society of America, 2020, 10 (12), pp.4637-4648. ⟨10.1534/g3.120.401537⟩
Li, J, Rinnerthaler, M, Hartl, J, Weber, M, Karl, T, Breitenbach-Koller, H, Mülleder, M, Vowinckel, J, Marx, H, Sauer, M, Mattanovich, D, Ata, Ö, De, S, Greslehner, G P, Geltinger, F, Burhans, B, Grant, C, Doronina, V, Ralser, M, Streubel, M K, Grabner, C, Jarolim, S, Moßhammer, C, Gourlay, C W, Hasek, J, Cullen, P J, Liti, G, Ralser, M & Breitenbach, M 2020, ' Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1-Yeast Suppressed by a Dominant Mutation in ATP3 ', G3: Genes, Genomes, Genetics (Bethesda), vol. 10, no. 12, pp. 4637-4648 . https://doi.org/10.1534/g3.120.401537
G3: Genes | Genomes | Genetics (G3)
G3: Genes|Genomes|Genetics
G3
G3, Genetics Society of America, 2020, 10 (12), pp.4637-4648. ⟨10.1534/g3.120.401537⟩
Li, J, Rinnerthaler, M, Hartl, J, Weber, M, Karl, T, Breitenbach-Koller, H, Mülleder, M, Vowinckel, J, Marx, H, Sauer, M, Mattanovich, D, Ata, Ö, De, S, Greslehner, G P, Geltinger, F, Burhans, B, Grant, C, Doronina, V, Ralser, M, Streubel, M K, Grabner, C, Jarolim, S, Moßhammer, C, Gourlay, C W, Hasek, J, Cullen, P J, Liti, G, Ralser, M & Breitenbach, M 2020, ' Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1-Yeast Suppressed by a Dominant Mutation in ATP3 ', G3: Genes, Genomes, Genetics (Bethesda), vol. 10, no. 12, pp. 4637-4648 . https://doi.org/10.1534/g3.120.401537
G3: Genes | Genomes | Genetics (G3)
A yeast deletion mutation in the nuclear-encoded gene, AFO1, which codes for a mitochondrial ribosomal protein, led to slow growth on glucose, the inability to grow on glycerol or ethanol, and loss of mitochondrial DNA and respiration. We noticed tha